Protein Alignment alpha-Est10 and cest-12

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_499576.4
• Gene: cest-12 / 176642
• WormBaseID: WBGene00013540
• Length: 850
• Species: Caenorhabditis elegans
• Alignment Length: 457
• Identity: 109/457 - (23%)
• Similarity: 187/457 - (40%)
• Gaps: 109/457 - (23%)

  Fly    24 FTNGDFIQQVISFKYE-QRKLSTAIYSVIKTKSGPVRGVKRN------TIWGGSYFSFEKIPFAK 81
            |:|      |.:.:|: |.:...:.|..:....|.|:|.:.|      .::.|...:|..||:.:
 Worm    15 FSN------VSNAQYQNQNQNQQSNYVTVSCSQGSVQGRQVNLGNDQSQLYSGQANAFTGIPYCQ 73

  Fly    82 PPVGDLRFKAPEAVEPWDQEL-DCTSPADKPLQTHMFFRK-----YAG---SEDCLYLNVYVKDL 137
            .|||:||.:.|:.:..::..| |.|           :||.     .||   :|||||||||....
 Worm    74 APVGNLRLQPPQPLNQFNTTLHDAT-----------YFRPKCPQLNAGGPTNEDCLYLNVYTPQA 127

  Fly   138 -QPDKLRPVMVWIYG-GGYQVG--EASRDMYSPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNV 198
             ..:....|:|.|.| .|:..|  :.:::.......:.:.:|:||:.||:|||||.:....  :|
 Worm   128 GNTNANLSVLVLIDGSNGFSNGGCDQNQEKGIISNLVQRQIVVVTMQYRIGALGFFTTYTN--SV 190

  Fly   199 PGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSV 263
            ..|.|:.||:.|:||::..|..|||:.|.||:.|:..|..:.....|||.::.|.::|||.||||
 Worm   191 QSNLGMLDQVQAMRWIKTEIVNFGGNPNQITVAGQDDGACAVSAHCLSPMSQNLFNQAIVQSGSV 255

  Fly   264 LCPWTQPP-----------------------------RNNWAYR---LAQKLGYTG-----DNKD 291
            ...:...|                             :||:.|:   :.....|..     |:..
 Worm   256 YSCYNPTPAVPTNPQVQVTTPRPMYDQSNTGYGNAGYQNNYGYQPQPITSTSSYNSANAQYDDPS 320

  Fly   292 KAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHR 356
            :.:.:.|.::|..:........:.|..|::.:.|              .|.:||.. ...:|
 Worm   321 QQLAQTLCNISPDQWNNGQTQNIQNCMKNYTVDF--------------FVNQQPGG-PNATW--- 367

  Fly   357 IPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGLQLKKAYFGDEP 421
              |:...|||           .|.::|.:...:..:|..:|...|..  .:|..:|.....|.:|
 Worm   368 --MIVRDTSF-----------LPGSIDSLTTRRPNIPIIIGTVQDED--ADYAFKLINTGKGSDP 417

  Fly   422 CN 423
            .|
 Worm   418 NN 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	103/431 (24%)
		Aes	<132..>279	CDD:223730	50/182 (27%)
cest-12	NP_499576.4	Abhydrolase	37..>400	CDD:389770	97/406 (24%)
		Abhydrolase	<678..774	CDD:389770

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900