Protein Alignment alpha-Est10 and Ces3b

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_653094.2
• Gene: Ces3b / 13909
• MGIID: 3644960
• Length: 571
• Species: Mus musculus
• Alignment Length: 585
• Identity: 162/585 - (27%)
• Similarity: 234/585 - (40%)
• Gaps: 150/585 - (25%)

  Fly     5 WVSLLRHFSLIPNKSVPKVFTNGDFIQQVISFKYEQRKLSTAIYSVIKTKSGPVR----GVKR-- 63
            ||:.|. .:.:...:.|||                       |...:.|..|.||    |||.
Mouse    17 WVTCLL-LAFVTTVTGPKV-----------------------IQPEVDTPLGRVRGRQVGVKDTD 57

  Fly    64 ---NTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELD-------CTSPADKPLQTHMFF 118
               |...|        ||||:.|||.|||.||...:||:...|       |....:|.:.:....
Mouse    58 RMVNVFLG--------IPFAQAPVGPLRFSAPLPPQPWEGVRDASINPPMCLQDVEKMINSRFGL 114

  Fly   119 RK----YAGSEDCLYLNVYVKDLQPDKL-----RPVMVWIYGGGYQVGEA-SRD-----MYSPDF 168
            .:    :..|||||.||:|    .|.::     |||||||:||...||.: |:|     .|.
Mouse   115 NEKIKIFPISEDCLTLNIY----SPTEITAGDKRPVMVWIHGGSLLVGSSTSQDGSALAAYG--- 172

  Fly   169 FMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGE 233
                |||:|||.||||..||||..|.  ::|||.|..|.:.||||||.||..||||.|.:|:||.
Mouse   173 ----DVVVVTVQYRLGIFGFLSTGDK--HMPGNRGFLDVVAALRWVQGNIAPFGGDPNCVTIFGN 231

  Fly   234 SAGGASTHFLALSPQTEGLIHKAIVMSGSV-------LCPWTQPPRNNWAYRLAQKLGYTGDNKD 291
            ||||.....|.|||.:.||.|:||..||.|       :.||  |...|:|..:|     .|....
Mouse   232 SAGGMIVSSLFLSPISAGLFHRAISQSGIVTTIMMEDMKPW--PEAQNFANSVA-----CGSASP 289

  Fly   292 KAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHR 356
            ..:.:.|....|.:::|.....:|                  |....:...::|.:|:.:.....
Mouse   290 AELVQCLLQKEGKDLIKQKNVNIS------------------YIVNDSFFPQRPEKLLADQQFPT 336

  Fly   357 IPMMFGGTSFE-GLLFYPEVSRRPATLDEVGNCKNLLPSDL---------GLNLDPKLRENYGLQ 411
            :|.:.|.|:.| |.|....::    .||::   ::|...||         .:.:.|::...
Mouse   337 VPYLLGVTNHEFGWLLLKSLN----ILDKL---EHLSREDLLEISRPFLAIMEVPPEIMPT---- 390

  Fly   412 LKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALN---RVRQSSAPTYLYRFDHDSKLCNAI 473
            :...|..:.....|....|.||.....|..|    .||   .:|.:..|.:||.|.|........
Mouse   391 VIDEYLDNGSDQSATRYAFQELLGDISFIIP----TLNFSKYLRDAGCPVFLYEFQHTPSSFAKF 451

  Fly   474 RIVLCGHQMRGVCHGDDLCYIF--------HSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPN 530
            :.......     |..:..::|        .|:|:...|.:..:...:| |:..|:.||..|:||
Mouse   452 KPAWVKAD-----HASENSFVFGGPFLTDESSLLAFPEATEEEKQLSLT-MMAQWSQFARTGNPN 510

  Fly   531  530
            Mouse   511  510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	155/541 (29%)
Ces3b	NP_653094.2	COesterase	36..547	CDD:395084	155/542 (29%)
		Prevents secretion from ER. /evidence=ECO:0000255	568..571