Protein Alignment alpha-Est10 and Gli

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_061510245.1
• Gene: Gli / 1277780
• VectorBaseID: AGAMI1_001484
• Length: 973
• Species: Anopheles gambiae
• Alignment Length: 595
• Identity: 163/595 - (27%)
• Similarity: 246/595 - (41%)
• Gaps: 152/595 - (25%)

  Fly    69 GSYFSFEKIPFAKPPVGDLRFKAPEAVEPWD--QELDCTSPADKPLQTHMFFRKYAGS------- 124
            |...:|..||:|.||..:.|||.|.....|.  |.:|......:|:|       |.|:
Mosquito   180 GKCSTFLGIPYALPPTHEGRFKPPRQHRGWQLVQAVDYGPACPQPVQ-------YTGATKGIRDM 237

  Fly   125 -EDCLYLNVYVKDLQPDKLR--PVMVWIYGGGYQVGEASRDMYSPDFFMSK--DVVIVTVAYRLG 184
             |||||||::..:.|....:  |||::|:||.:..|.::.   .|...::.  |||:||..||||
Mosquito   238 DEDCLYLNIFSPNTQAGVAQRYPVMIYIHGGEFVRGASNT---FPGHMLAAFYDVVVVTFNYRLG 299

  Fly   185 ALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQT 249
            ||||||..|.  |.|||.|:.|||||:|||.:|||:|.||.|:|||||..|||||...|.::|||
Mosquito   300 ALGFLSTGDE--NSPGNYGILDQIMAVRWVYENIESFNGDRNSITLFGPGAGGASAGLLMVAPQT 362

  Fly   250 EGLIHKAIVMSGSVLCPWT----QPPRNNWAYRLAQKLGYTGDNKDKAIFEFLRSMSGGEIVKAT 310
            :.::.:.|..|||.|..|.    :....|.:...||.:|.:.:..    ::.:..|..|.    :
Mosquito   363 KDIVTRVIGQSGSALADWALIVDKWRAQNTSRVFAQNVGCSIETS----WKMVNCMRNGR----S 419

  Fly   311 ATVLSNDE-KHHRILFAFGPVVEPYTT-------------EHTVVAKQPHELMQNSWSHRIPMMF 361
            :..|.|.| ..|..||.:|||:|...|             :...:|:.|..|::....:|
Mosquito   420 SYELGNAEFPPHVGLFPWGPVLENNFTFPGDSWYEGWSERDWHFLAETPESLIRRRHFNR----- 479

  Fly   362 GGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPK----------LRENYGLQLKKAY 416
                  ||.:...|:.:.|.....|| |:|.|.   ..:|.:          ||.||.|.|...|
Mosquito   480 ------GLHYMSGVTLQEAAFVITGN-KSLAPY---FEVDERFFDQKVRELVLRYNYTLNLNGTY 534

  Fly   417 --------FGDEPCNQANMM-KFLELCSYREFWHPIYRAALNR----VRQSSAPTYLYRFDHDSK 468
                    :..:|.|...:. :::.|.|  :|   :|||..::    :.:.:.|.|.|
Mosquito   535 EAIKYMYTYWPDPKNTTFIREQYINLLS--DF---LYRAPTDKLIKLLVEQNVPVYSY------- 587

  Fly   469 LCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITG--MVDV------------ 519
               .:...:.|.::...|                ..|...||.::.|  .:||
Mosquito   588 ---VMNTTIEGLKLAEWC----------------KVPHDIEHYLLAGAPFMDVEFFPRRERFDRL 633

  Fly   520 -WT---------------SFAAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQKI 568
             ||               .||.||:|....:..|.|....| ...|.||:...:....:...::.
Mosquito   634 MWTDNDRNMSHFFMKTYSDFARHGNPTPTQVLGLYFEKARN-GELKYLNLNTTYNSTIMMNYRQT 697

  Fly   569 EPVWNSFYAP 578
            |..:...|.|
Mosquito   698 ESAFWMEYLP 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	154/548 (28%)
Gli	XP_061510245.1	None