DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est10 and AADACL3

DIOPT Version :10

Sequence 1:NP_001246962.1 Gene:alpha-Est10 / 40896 FlyBaseID:FBgn0015569 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001096640.2 Gene:AADACL3 / 126767 HGNCID:32037 Length:407 Species:Homo sapiens


Alignment Length:22 Identity:6/22 - (27%)
Similarity:9/22 - (40%) Gaps:0/22 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 VYIGYLTFALNRLTSALNISSY 119
            ::||...|..|...:|.....|
Human   149 IHIGEKPFKCNECGTAFGQKKY 170

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est10NP_001246962.1 COesterase 49..533 CDD:395084 6/22 (27%)
AADACL3NP_001096640.2 Abhydrolase_3 115..378 CDD:400284 6/22 (27%)
Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3 119..121
Blue background indicates that the domain is not in the aligned region.

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