Protein Alignment alpha-Est10 and Nlgn1

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_038957495.1
• Gene: Nlgn1 / 116647
• RGDID: 621117
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 651
• Identity: 175/651 - (26%)
• Similarity: 251/651 - (38%)
• Gaps: 180/651 - (27%)

  Fly    50 VIKTKSGPVRGVKR---NTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPA--- 108
            ::.|..|.:||:|:   |.|. |....|..:|:|.||.|:.||:.||...||....:.|..|
  Rat    54 LVTTNFGKIRGIKKELNNEIL-GPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVC 117

  Fly   109 -----DKPLQTHMF----------FRKYA--GSEDCLYLNVYV--KDL----------------- 137
                 |..|...|.          ...|.  .||||||||:||  :|:
  Rat   118 PQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICR 182

  Fly   138 --------QPDKL-----------------RPVMVWIYGGGYQVGEASRDMYSPDFFMS-KDVVI 176
                    |.|.|                 :||||:|:||.|.  |.:.::|......| .:|::
  Rat   183 KGGPLTKTQTDDLGDNDRAEDEDIRDSGGPKPVMVYIHGGSYM--EGTGNLYDGSVLASYGNVIV 245

  Fly   177 VTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTH 241
            :||.||||.|||||..|..  ..||.||.|.|.||||..:||..||||...||:||..|||:..:
  Rat   246 ITVNYRLGVLGFLSTGDQA--AKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVN 308

  Fly   242 FLAL---------SPQTEGLIHKAIVMSGSVLCPWT---QPPRNNWAYRLAQKLGYTGDNKDKAI 294
            .|.|         |..|:||..:||..||:.|..|.   ||.:  :|..||.|:|....:..:.:
  Rat   309 LLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAK--YARILATKVGCNVSDTVELV 371

  Fly   295 FEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPM 359
             |.|:.....|:|       ..|.:..|...|||||:     :..|:...|..||:........:
  Rat   372 -ECLQKKPYKELV-------DQDVQPARYHIAFGPVI-----DGDVIPDDPQILMEQGEFLNYDI 423

  Fly   360 MFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLD----------------PK----L 404
            |.|....|||.|                .:|::.||.|::..                |:    |
  Rat   424 MLGVNQGEGLKF----------------VENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVL 472

  Fly   405 RENYGLQLKKAY--FGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDS 467
            ||.    :|..|  :.|....:......|.|.:..::..|.. |..:......:|||.|.|.|.
  Rat   473 RET----IKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAV-ATADLHSNFGSPTYFYAFYHH- 531

  Fly   468 KLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPD-------SPEHKVITGMV-DVWTSFA 524
              |...::    .......|||::.|:....:   ..|.       |....:::.:| ..||:||
  Rat   532 --CQTDQV----PAWADAAHGDEVPYVLGIPM---IGPTELFPCNFSKNDVMLSAVVMTYWTNFA 587

  Fly   525 AHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQK---------IEPVWNSFYAPNK 580
            ..||||....:..||  |....|        :||.:|.....:         ::|.....|..||
  Rat   588 KTGDPNQPVPQDTKF--IHTKPN--------RFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANK 642

  Fly   581 L 581
            :
  Rat   643 V 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	164/592 (28%)
Nlgn1	XP_038957495.1	COesterase	52..646	CDD:395084	175/651 (27%)