Protein Alignment alpha-Est10 and Ache

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 565
• Identity: 168/565 - (29%)
• Similarity: 245/565 - (43%)
• Gaps: 77/565 - (13%)

  Fly    50 VIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPADKPLQ- 113
            :::.:.|.:||::.... ||...:|..||||:||||..||..||...||...||.|:..:...|
Mouse    40 LVRVRGGQLRGIRLKAP-GGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQY 103

  Fly   114 ----------THMFFRKYAGSEDCLYLNVYVKDLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDF 168
                      |.|:......|||||||||:....:|....||::||||||:..|.||.|:|...|
Mouse   104 VDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRF 168

  Fly   169 FMS-KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFG 232
            ... :..|:|::.||:|..|||:|...: ..|||.||.||.:||:|||:||.|||||..::||||
Mouse   169 LAQVEGAVLVSMNYRVGTFGFLALPGSR-EAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFG 232

  Fly   233 ESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWAYRLAQKL--------GYTGDN 289
            ||||.||.....||..:..|.|:|::.||:...||....... |.|.|..|        |..|.|
Mouse   233 ESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGE-ARRRATLLARLVGCPPGGAGGN 296

  Fly   290 KDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWS 354
             |..:...||:....::|.....||..:....   |:|.|||     :...::..|..|:.....
Mouse   297 -DTELIACLRTRPAQDLVDHEWHVLPQESIFR---FSFVPVV-----DGDFLSDTPEALINTGDF 352

  Fly   355 HRIPMMFGGTSFEGLLF----YPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKL-RENYGLQLKK 414
            ..:.::.|....||..|    .|..|:...:|  :...:.|....:|:.....| .|...|....
Mouse   353 QDLQVLVGVVKDEGSYFLVYGVPGFSKDNESL--ISRAQFLAGVRIGVPQASDLAAEAVVLHYTD 415

  Fly   415 AYFGDEPCNQANMMKFL-----ELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIR 474
            ....::|.:..:.|..:     .:|       |:.:.| .|:....|..|.|.|:|.:.
Mouse   416 WLHPEDPTHLRDAMSAVVGDHNVVC-------PVAQLA-GRLAAQGARVYAYIFEHRAS------ 466

  Fly   475 IVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPN-CESIKSLK 538
             .|......||.||.::.:||...|.......:.|......::..||:||..|||| ....||.:
Mouse   467 -TLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQ 530

  Fly   539 FAPIENVT------NFKCLNI--GDQFEVMALPELQKIEPVWNSF 575
            :.|.....      |.|.|.:  |.:.:..|.         ||.|
Mouse   531 WPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAF---------WNRF 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	159/522 (30%)
		Aes	<132..>279	CDD:223730	64/147 (44%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	165/560 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832863
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840