DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est10 and Ces1d

DIOPT Version :10

Sequence 1:NP_001246962.1 Gene:alpha-Est10 / 40896 FlyBaseID:FBgn0015569 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_579829.3 Gene:Ces1d / 113902 RGDID:70896 Length:565 Species:Rattus norvegicus


Alignment Length:530 Identity:164/530 - (30%)
Similarity:233/530 - (43%) Gaps:111/530 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 NTIWG---GSYFSFE----------KIPFAKPPVGDLRFKAPEAVEPWD---------------- 99
            ||:.|   |.|.:.|          .|||||||:|.|||..|:..|||:                
  Rat    27 NTVKGKVLGKYVNLEGFAQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWNFVKNTTSYPPMCSQDA 91

  Fly   100 ------QELDCTSPADKPLQTHMFFRKYAGSEDCLYLNVYV-KDLQPDKLRPVMVWIYGGGYQVG 157
                  .||......:.|||.         ||||||||||. .||..:...||||||:|||..||
  Rat    92 VGGQVLSELFTNRKENIPLQF---------SEDCLYLNVYTPADLTKNSRLPVMVWIHGGGLVVG 147

  Fly   158 EASRDMYSPDFFMS-KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAF 221
            .||  .|......: ::||:||:.||||..||.|..|.  :..||.|..||:.||.|||.||..|
  Rat   148 GAS--TYDGQVLSAHENVVVVTIQYRLGIWGFFSTGDE--HSQGNWGHLDQVAALHWVQDNIANF 208

  Fly   222 GGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPW-----TQPPRNNWAYRLAQ 281
            ||:..::|:|||||||.|...|.|||..:.|.|:||..||.||...     ::|..|     |..
  Rat   209 GGNPGSVTIFGESAGGFSVSALVLSPLAKNLFHRAISESGVVLTSALITTDSKPIAN-----LIA 268

  Fly   282 KLGYTGDNKDKAIFEFLRSMSGGEIVKAT-------ATVLSNDEKHHRILFAFGPVVEPYTTEHT 339
            .|..........:...||..:..|:::.:       ..:|.|.::.:..|        |...:..
  Rat   269 TLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFL--------PTVIDGV 325

  Fly   340 VVAKQPHELMQNSWSHRIPMMFG------GTSFEGLLFYPEVSRRPATLDEVGNCKNLL----PS 394
            |:.|.|.|::.....:.:|.:.|      |.....|:.||   .....||: ...|:||    |:
  Rat   326 VLPKTPEEILTEKSFNTVPYIVGINKQEFGWIIPTLMGYP---LSEGKLDQ-KTAKSLLWKSYPT 386

  Fly   395 DLGLNLDPKLRENYGLQLKKAYFG--DEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAP 457
                   .|:.|.....:.:.|||  |:|..:.::  |.:|.:...|..|....:.:. |.:.||
  Rat   387 -------LKISEKMIPVVAEKYFGGTDDPAKRKDL--FQDLVADVMFGVPSVMVSRSH-RDAGAP 441

  Fly   458 TYLYRFDHDSKLCNAIR-IVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMV-DVW 520
            |::|.|::.....:|:| ..:.|.      |||:|..:|.|......|  |.|...::.|| ..|
  Rat   442 TFMYEFEYRPSFVSAMRPKTVIGD------HGDELFSVFGSPFLKDGA--SEEETNLSKMVMKYW 498

  Fly   521 TSFAAHGDPN 530
            .:||.:|.||
  Rat   499 ANFARNGSPN 508

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est10NP_001246962.1 COesterase 49..533 CDD:395084 164/530 (31%)
Ces1dNP_579829.3 COesterase 22..545 CDD:395084 164/530 (31%)
Prevents secretion from ER. /evidence=ECO:0000255 562..565
Blue background indicates that the domain is not in the aligned region.

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