Protein Alignment alpha-Est10 and nlgn1

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 641
• Identity: 172/641 - (26%)
• Similarity: 251/641 - (39%)
• Gaps: 160/641 - (24%)

  Fly    50 VIKTKSGPVRGVKR---NTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPADKP 111
            ::.|..|.|||.|:   |.|. |....|..:|:|.||.|:.||:.||....|.:..:.|..|...
Zfish    55 IVTTTYGKVRGFKKELNNEIL-GPVIQFLGVPYAAPPTGERRFQPPEPPISWSEIRNATQFAPVC 118

  Fly   112 LQTHMFFR------------------KYA--GSEDCLYLNVYV--KDL----------------- 137
            .||.:..|                  .|.  .|||||:||:||  :|:
Zfish   119 PQTLLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYVPTEDVKRISKECARKPGKKICR 183

  Fly   138 --------QPDKL-----------------RPVMVWIYGGGYQVGEASRDMYSPDFFMS-KDVVI 176
                    |.|.|                 :||||:::||.|.  |.:.:|:......| .:|::
Zfish   184 KGGPLSKKQNDDLADNDGAEDEDIRESGSPKPVMVFVHGGSYM--EGTGNMFDGSILASYGNVIV 246

  Fly   177 VTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTH 241
            :||.||||.|||||..|..  ..||.||.|.|.||||..:||..||||...||:||..||.:..:
Zfish   247 ITVNYRLGVLGFLSTGDQA--AKGNYGLLDLIQALRWTSENIAFFGGDPLRITVFGSGAGASCVN 309

  Fly   242 FLAL---------SPQTEGLIHKAIVMSGSVLCPWT---QPPRNNWAYRLAQKLGYTGDNKDKA- 293
            .|.|         |..|:||..:||..||:.|..|.   ||.:  :|..||:|:|.  :.||..
Zfish   310 LLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAK--YARMLAKKVGC--NLKDTVE 370

  Fly   294 IFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIP 358
            :.|.|:.....|:|:       .|.:..|...|||||:     :..|:...|..||:........
Zfish   371 MVECLQKKHYKELVE-------QDIQPARYHIAFGPVI-----DGDVIPDDPQILMEQGEFLNYD 423

  Fly   359 MMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGL---------QLKK 414
            :|.|....|||.|...:         |.|...:..:|....:...:.:.||.         .:|.
Zfish   424 IMLGVNQGEGLKFVELI---------VDNENGVQANDFDYAVSSFVDDLYGYPEGKDILRETIKF 479

  Fly   415 AY--FGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVL 477
            .|  :.|....:......|.|.:..::..|.. |..:......:|||.|.|.|.   |...::
Zfish   480 MYTDWADRHNPETRRKTLLALFTDHQWVAPAV-ATADLHSSFGSPTYFYAFYHH---CQTEQV-- 538

  Fly   478 CGHQMRGVCHGDDLCYIFHSMLSHQSAPD-------SPEHKVITGMV-DVWTSFAAHGDPNCESI 534
              .......|||::.|:|...:   ..|.       |....:::.:| ..||:||..||||....
Zfish   539 --PPWADAAHGDEIPYVFGLPM---IGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVP 598

  Fly   535 KSLKFAPIENVTNFKCLNIGDQFEVMALPELQK---------IEPVWNSFYAPNKL 581
            :..||  |....|        :||.:|.....:         ::|.....|..||:
Zfish   599 QDTKF--IHTKPN--------RFEEVAWTRYNQKDQLYLHIGLKPRVKEHYRANKV 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	161/582 (28%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:395084	172/641 (27%)