Protein Alignment alpha-Est10 and nlgn2b

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 627
• Identity: 182/627 - (29%)
• Similarity: 259/627 - (41%)
• Gaps: 165/627 - (26%)

  Fly    39 EQRKLSTAIYSVIKTKSGPVRGVKR---NTIWG--GSYFSFEKIPFAKPPVGDLRFKAPEAVEPW 98
            ::..|:||.:.::.|..|.:|||::   |.|.|  ..|..   :|:|.||||:.||:.|||...|
Zfish    42 QRADLTTAKHPMVTTGYGKLRGVRKELNNEILGPVEQYLG---VPYATPPVGERRFQPPEAPGSW 103

  Fly    99 DQELDCTSPADK-PLQTH---------MFFRKYAG---------SEDCLYLNVYV---------- 134
            .:..:.|..|.. |...|         ::|.....         |||||||||||
Zfish   104 QEIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQNQSEDCLYLNVYVPTEDGPLTKK 168

  Fly   135 -----------KDLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFMS-KDVVIVTVAYRLGALG 187
                       :|::..:.:|||::|:||.:.  |.:.:|:......: .:|::||:.||||.||
Zfish   169 HDESSMNRPRDEDIRDRRKKPVMLFIHGGSFM--EGTGNMFDASVLAAYGNVIVVTMNYRLGVLG 231

  Fly   188 FLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGL 252
            |||..|.  :..||.||.|||.||||:.:||..||||...||:||..||.:..:.|.||..:|||
Zfish   232 FLSSGDQ--SAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGL 294

  Fly   253 IHKAIVMSGSVLCPWTQPPRNNWAYR-------LAQKLGYT-GDNKDKAIFEFLRSMSGGEIVKA 309
            ..:||..|||.:..|:.      .||       ||:|:|.: .|..|  :.:.||..|..|:|
Zfish   295 FQRAIAQSGSAISSWSV------NYRPLMYTKILAKKVGCSYSDTAD--LVDCLRRKSYRELV-- 349

  Fly   310 TATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYP- 373
                 ..|.:..|...||||||     :..||...|..|||........::.|....|||.|..
Zfish   350 -----DQDVQPARYHIAFGPVV-----DGDVVPDDPEILMQQGEFLNYDILLGVNQGEGLKFVDD 404

  Fly   374 ---EVSRRPATLD-EVGN-CKNLLPSDLGLNLDPKLRENYGLQLKKAY--FGDEPCNQANMMKFL 431
               |.....|:.| .:.| ..||.....|.::   |||.    :|..|  :.|...........|
Zfish   405 NEGEEGISAASFDYTISNFVDNLYGYPEGKDI---LRET----IKFMYTDWADRDNGDMRRKTLL 462

  Fly   432 ELCSYREFWHP-IYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMR----GVCHGDDL 491
            .|.:..::..| :..|.|:...||  |.|.|.|.|.           |..:.|    ...|||::
Zfish   463 ALFTDHQWVAPAVATAKLHAEFQS--PVYFYTFHHH-----------CQTEARPEWADAAHGDEI 514

  Fly   492 CYIF------------------HSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPNCESIKSLK 538
            .|:|                  ..|||             ..::..||:||..||||....:..|
Zfish   515 PYVFGVPMVGATELFPCNFSKNDIMLS-------------AVVMTYWTNFAKTGDPNIPVPQDTK 566

  Fly   539 FAPIENVTNFKCLNIGDQFEVMALPELQKIEPVWNSFYAPNK 580
            |  |....|        :||          |.:|..|.:.:|
Zfish   567 F--IHTKPN--------RFE----------EVIWTKFSSKDK 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	171/577 (30%)
		Aes	<132..>279	CDD:223730	62/175 (35%)
nlgn2b	NP_001159808.1	COesterase	47..611	CDD:278561	181/622 (29%)
		Aes	<181..>279	CDD:223730	44/101 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740