DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir84a and GLR3.6

DIOPT Version :9

Sequence 1:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_001326369.1	Gene:	GLR3.6 / 824311	AraportID:	AT3G51480	Length:	903	Species:	Arabidopsis thaliana

Alignment Length:	788	Identity:	150/788 - (19%)
Similarity:	264/788 - (33%)	Gaps:	234/788 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FLRVLQIESINTNFLELAAFEDFLRSEHLSHVLVVRGDD--------ADGDWKIECHQKLLANYR 75
            |:|..|     .:..::||..|.::......|:.:.|||        |.||...|  ::...:|:
plant   139 FIRTSQ-----NDLFQMAAIADIVQFYGWREVVAIYGDDDYGRNGVAALGDRLSE--KRCRISYK 196

  Fly    76 VQFYRPEMSANFEDLMF-YGSPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWF-------I 132
            ..........|..||:. .....:.::|:::..:. ..::|.||...|..:....|.       |
plant   197 AALPPAPTRENITDLLIKVALSESRIIVVHASFIW-GLELFNVARNLGMMSTGYVWIATNWLSTI 260

  Fly   133 LGSGRESLPVEQLIDQLLSGYRMGIDADITVALRGPDNA--------------------SMLFYD 177
            :.:. ..||::.:         ..|...||:.|..|::.                    ::..||
plant   261 IDTD-SPLPLDTI---------NNIQGVITLRLHTPNSIMKQNFVQRWHNLTHVGLSTYALYAYD 315

  Fly   178 VYRISRQA--------------NTPLIIEKKGLWTHSGGYQKFGNFKNTWVIRRRNFLNVTLIGS 228
            ...:..||              ..|:|.|..|...|....:.|...|    |...:.|.|..||.
plant   316 TVWLLAQAIDDFFKKGGNVSFSKNPIISELGGGNLHLDALKVFDGGK----IFLESILQVDRIGL 376

  Fly   229 T-----------------VLTEKPPGFGDMEYLADDKQLQQL--DPMQRKTYQLFQL-------- 266
            |                 ||.....|:..:.|..:...|..:  |.|:..::...:|
plant   377 TGRMKFTSDRNLVNPAFDVLNVIGTGYTTIGYWFNHSGLSVMPADEMENTSFSGQKLHSVVWPGH 441

  Fly   267 --------------------VERMFNLSLAISLTDK----------------------------W 283
                                |...:.....:|:...                            :
plant   442 SIKIPRGWVFSNNGRHLRIGVPNRYRFEEVVSVKSNGMITGFCVDVFIAAINLLPYAVPFELVAF 506

  Fly   284 GELLDNGSWSGVMGQVTSREADFAVCPIRFVLDR-------QPYVQYSAVLHTQNIHFLFRHPRR 341
            |...||.|.|.::..:|:...|..|..|..:.:|       ||||:...|:..         |.|
plant   507 GNGHDNPSNSELVRLITTGVYDAGVGDITIITERTKMADFTQPYVESGLVVVA---------PVR 562

  Fly   342 --SHIKNIFFEPLSNQVWWCVLA--LVTGSTILLLFHVRLE--------RMLSNMENRFSFVWFT 394
              ......|..|.:.|:|....|  |:.|:.|..|.|...:        ::::.....||.::|:
plant   563 KLGSSAMAFLRPFTPQMWLIAAASFLIVGAVIWCLEHKHNDEFRGPPRRQVITTFWFSFSTLFFS 627

  Fly   395 MLETYLQQGPANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYDSNL 459
            ..||     ..:.:.|:    :||    |:.|:::      |:.|..:.|..||:.:..|  |:.
plant   628 HRET-----TTSNLGRI----VLI----IWLFVVL------IINSSYTASLTSILTVHQL--SSP 671

  Fly   460 AIGMENISYNFPIFTNTSNQLVRD-------VYVKKI--CKSGEHNIMSLQQGAERIIQGRFAFH 515
            ..|:|.:..|...........|||       ::|.::  .:|.|....:|:.|     .|:....
plant   672 IKGIETLQTNHDPIGYPQGSFVRDYLIHELNIHVSRLVPLRSPEEYDKALRDG-----PGKGGVA 731

  Fly   516 TAIDRMYRLLLELQMDEAEFCDL----QEVMFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLL 576
            ..:|.  |..:||.:...  |:.    ||...|   ..|...|:.||....::.|:|.....|.:
plant   732 AVVDE--RAYIELFLSNR--CEFGIVGQEFTKN---GWGFAFPRNSPLAVDVSAAILQLSENGDM 789

  Fly   577 QYNDKKWMVRRPDCSLFKTSQAEVD---LEHFAPALFALALAMVASALVF---LLELFLHWLPD- 634
            |....||::|:. ||| :.::.|||   |:.|........:|.|.:..|:   ::..|....|:
plant   790 QRIRDKWLLRKA-CSL-QGAEIEVDRLELKSFWGLFVVCGVACVLALAVYTVLMIRQFGQQCPEE 852

  Fly   635 ----FRRR 638
                .|||
plant   853 AEGSIRRR 860

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020	12/66 (18%)
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	86/467 (18%)
		Lig_chan	355..602	CDD:278489	62/272 (23%)
GLR3.6	NP_001326369.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100