Protein Alignment Ir84a and gria1a

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_991161.1
• Gene: gria1a / 798689
• ZFINID: ZDB-GENE-020125-1
• Length: 914
• Species: Danio rerio
• Alignment Length: 759
• Identity: 149/759 - (19%)
• Similarity: 277/759 - (36%)
• Gaps: 218/759 - (28%)

  Fly    20 LRVLQ------------IESINTNFLE----LAAFEDFLRS-----------EHLSHVL---VVR 54
            |.|||            :.|:|...:.    |..|:|..:.           |.|:.:|   :..
Zfish   154 LSVLQKVLDTAAEHNWLVTSVNVETMTEASFLKVFQDLDKKKEGQIIIDCELERLTSILKKIIEL 218

  Fly    55 GDDADGDWKIECHQKLLANY------RVQFYRPEMSANFEDLMFYGSPRTA-------------- 99
            |.:      ::.:..:|||.      ..:|.:.|.:.....|:.|..|..:
Zfish   219 GKN------VKSYHYILANLGFLDIDLTEFKKGEANVTGFQLVNYADPNVSRTVQQWMEFDNKDA 277

  Fly   100 -----------------VLVLNSEHVLVRRQVFGVASEAGYFNNSLA-----WFILGSGRESLPV 142
                             |.|:::....:|||...: |..|.....||     |   |.|   :.:
Zfish   278 KVPKRRLKYTGALTYDGVKVMSTAFQNLRRQRIDI-SRRGNAGECLANPPAPW---GQG---IDI 335

  Fly   143 EQLIDQLLSGYRM-GIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTH------S 200
            ::.:.|:    |: |:...|....:|....       |.||.....|...:|.|.|..      :
Zfish   336 QRALQQV----RIEGLTGHIQFNEKGRRTN-------YSISVMELRPTGPKKVGYWNEDEKFVST 389

  Fly   201 GGYQKFGNFKNTWVIRRRNFLNVTLIGST-VLTEKPPGFGDMEYLADDKQLQQLDPMQRKTYQLF 264
            ..|....|  .|:.::.|.::..|::.|. |:.:|    ....:..:||            |:.:
Zfish   390 AAYMPGSN--ETYGLQNRTYIVTTILESPYVMLKK----NHEHFTGNDK------------YEGY 436

  Fly   265 ------QLVERM-FNLSLAISLTDKWGEL-LDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYV 321
                  ::.:.: ::..|.|....|:|.. .:...|:|::|::...:||.||.|:...|.|:..:
Zfish   437 CVELAAEIAKHVGYHYILKIVADGKYGARDAETMMWNGMVGELVYGKADVAVAPLTITLVREEVI 501

  Fly   322 QYSAVLHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLE------- 378
            .:|....:..|..:.:.|.:|..... |.:||:.::|.|::....|.:::|....|..
Zfish   502 DFSKPFMSLGISIMIKKPTKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHAD 566

  Fly   379 ------------------RMLSNMENR-------------FSFVWFTMLETYLQQG----PANEI 408
                              :...|.:|:             |:.:||: |..::|||    |
Zfish   567 DCEDGAEENPNQPSSSSAQPGQNQQNQNQQSQEQTNEFGIFNSLWFS-LGAFMQQGCDISP---- 626

  Fly   409 FRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYD----SNLAIGMENISYN 469
             |..|.|::..:...|:.:::..|.|.:...|..|  |.:..:::..|    :.:|.|..:....
Zfish   627 -RSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVE--RMVSPIESAEDLAKQTEIAYGTLDAGST 688

  Fly   470 FPIFTNTSNQLVRDVYVKKICKSGEHNIM--SLQQGAERI--IQGRFAFHTAIDRMYRLLLELQM 530
            ...|..:...:...::  ...||.:.::.  :..:|..|:  .:|::|:          |||..|
Zfish   689 KEFFRRSKIAVFEKMW--SYMKSADPSVFVKTTDEGVMRVRKSKGKYAY----------LLESTM 741

  Fly   531 DE----AEFCDLQEVMFNLPYDS---GSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRP 588
            :|    .:.||..:|..||  ||   |...|||||.|..:..|:|.....|||.....||...:.
Zfish   742 NEYIEQRKPCDTMKVGGNL--DSKGYGIATPKGSPLRNPVNLAVLKLNEQGLLDKLKNKWWYDKG 804

  Fly   589 DC------SLFKTSQAEVDLEHFAPALFALALAMVASALVFLLE 626
            :|      |..|||  .:.|.:.|...:.|...:..:.||.|:|
Zfish   805 ECGSGGGDSKDKTS--ALSLSNVAGVFYILIGGLGLAMLVALVE 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	11/94 (12%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	19/74 (26%)
		Lig_chan	353..602	CDD:459656	65/311 (21%)
gria1a	NP_991161.1	Periplasmic_Binding_Protein_type1	26..390	CDD:471960	45/259 (17%)
		PBP2_iGluR_AMPA_GluR1	404..806	CDD:270447	89/439 (20%)
		Lig_chan	536..835	CDD:459656	68/322 (21%)