Protein Alignment Ir84a and grin2aa

DIOPT Version :9

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_021329529.1
• Gene: grin2aa / 563297
• ZFINID: ZDB-GENE-070424-129
• Length: 1460
• Species: Danio rerio
• Alignment Length: 534
• Identity: 96/534 - (17%)
• Similarity: 187/534 - (35%)
• Gaps: 145/534 - (27%)

  Fly   189 LIIEKKGLWTHSGGYQKFGNFKNTWVIRRRNFLNVTLIGSTVLTEKPP------GFGDMEYLADD 247
            :::.|...|      :|.|.::|                 ..||.|.|      .|||.|  .||
Zfish   361 IVLNKDREW------EKMGKWEN-----------------QSLTLKYPVWPRFNSFGDAE--TDD 400

  Fly   248 KQLQQLDPMQRKTYQLFQLVERM------------------------------------------ 270
            ..| .:..::.|.:.:.:.|||:
Zfish   401 NHL-TIVTLEEKPFVIVENVERLTGTCMRNSVPCRKHIKDNTTEGGGTYIKKCCKGFCIDILKKI 464

  Fly   271 -----FNLSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQ 330
                 |...|.:....|.|:.::| .|:|::|:|.:::|..||..:....:|...:.:|......
Zfish   465 ARNVKFTYDLYLVTNGKHGKKINN-VWNGMVGEVVNKKAVMAVGSLTINEERSEVIDFSVPFVET 528

  Fly   331 NIHFLFRHPRRSHIKNIFFEPLSNQVW---WCVLALVTGSTILLLFHVR---LERMLS------- 382
            .|..:......:...:.|.||.|..||   :.:|.|||...:.:..::.   ..|.|:
Zfish   529 GISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLLVTAMAVFMFEYISPLGFNRNLAQGKDPHG 593

  Fly   383 ---NMENRFSFVWFTMLETYLQ-QGPANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSE 443
               .|......:|..:....:. |.|...     :::.::|:...|:.:.:..|.|.:...::.|
Zfish   594 PSFTMGKAVWLLWGLVFNNSVPVQNPKGT-----TSKFIVSVWAFFAVIFLASYTANLAAFMIQE 653

  Fly   444 ------SARSIVNLQALYDSN--LAIGM-------ENISYNFPIFTNTSNQLVRDV--YVKKICK 491
                  :..|....|:.|..:  ...|.       .||..|:|           |:  |:.|..:
Zfish   654 EFVDQVTGLSDKKFQSPYSYSPPFRFGTVPNGSTERNIRKNYP-----------DMHQYMVKYHQ 707

  Fly   492 SGEHN-IMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDEAEFCDLQEVMFNLPYDS---GSV 552
            :|.:: ::||:.|.    ...|.:..|:       |.......|.|.|..:.....:.:   |..
Zfish   708 TGVNDALVSLKTGK----LDAFIYDAAV-------LNYMAGRDEGCKLVTIGSGYIFATTGYGIA 761

  Fly   553 MPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAEVDLEHFAPALFALALAMV 617
            :.|||.|:..:..|:|.....|.::..:.:|:.........:...:::|:::.|...:.||.||.
Zfish   762 LQKGSLWKRPVDLAILAIIGDGEMEELEAQWLTGICHNEKNEVMSSQLDVDNMAGVFYMLATAMG 826

  Fly   618 ASALVFLLELFLHW 631
            .|.:.|:.|...:|
Zfish   827 LSLITFVWEHLFYW 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	80/451 (18%)
		Lig_chan	355..602	CDD:278489	47/284 (17%)
grin2aa	XP_021329529.1	PBP1_iGluR_NMDA_NR2	33..389	CDD:107373	9/50 (18%)
		PBP2_iGluR_NMDA_Nr2	400..799	CDD:270436	72/427 (17%)
		NMDAR2_C	836..1460	CDD:313729	1/5 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591441
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930