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Protein Alignment Ir84a and Gria3

DIOPT Version :9

Sequence 1:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_001268858.2	Gene:	Gria3 / 53623	MGIID:	95810	Length:	888	Species:	Mus musculus

Alignment Length:	602	Identity:	143/602 - (23%)
Similarity:	245/602 - (40%)	Gaps:	131/602 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 YGSPRT--AVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFILGSGRESLPVEQLIDQLLSGYRM 155
            |.|..|  |:||:......:|||...| |..|...:.||       ..::|..|
Mouse   299 YTSALTHDAILVIAEAFRYLRRQRVDV-SRRGSAGDCLA-------NPAVPWSQ----------- 344

  Fly   156 GIDADITVALRGPDNASM---LFYDVYRISRQANTPLII--------EKKGLWTHSGGYQKFGNF 209
            ||  ||..||:......|   :.:|.|  .|:.|..:.:        .|.|.|..   |::|..|
Mouse   345 GI--DIERALKMVQVQGMTGNIQFDTY--GRRTNYTIDVYEMKVSGSRKAGYWNE---YERFVPF 402

  Fly   210 KNTWVIR-RRNFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQR-------KTYQLFQL 266
            .:..:.. ..:..|.|::.:|:| |.|       |:...|..:||:..:|       ..|::.:.
Mouse   403 SDQQISNDSSSSENRTIVVTTIL-ESP-------YVMYKKNHEQLEGNERYEGYCVDLAYEIAKH 459

  Fly   267 VERMFNLSLAISLTDKWGEL-LDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQ 330
            |...:.||:...  .|:|.. .:...|:|::|::....||.||.|:...|.|:..:.:|....:.
Mouse   460 VRIKYKLSIVGD--GKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSL 522

  Fly   331 NIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLERMLSNMENR------- 387
            .|..:.:.|::|..... |.:||:.::|.|::....|.:::|....|......::|:.
Mouse   523 GISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDP 587

  Fly   388 ------------FSFVWFTMLETYLQQG----PANEIFRLFSTRLLISLSCIFSFMLMQFYGAFI 436
                        |:.:||: |..::|||    |     |..|.|::..:...|:.:::..|.|.:
Mouse   588 QSPPDPPNEFGIFNSLWFS-LGAFMQQGCDISP-----RSLSGRIVGGVWWFFTLIIISSYTANL 646

  Fly   437 VGSLLSESARSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQLVR----DVYVK--KICKSGEH 495
            ...|..|  |.:..:::..|  ||...| |:|. .:.:.::.:..|    .||.|  ...||.|.
Mouse   647 AAFLTVE--RMVSPIESAED--LAKQTE-IAYG-TLDSGSTKEFFRRSKIAVYEKMWSYMKSAEP 705

  Fly   496 NIM--SLQQGAERI--IQGRFAFHTAIDRMYRLLLELQMDE----AEFCDLQEVMFNLPYDS--- 549
            ::.  :...|..|:  .:|:|||          |||..|:|    .:.||..:|..||  ||
Mouse   706 SVFTKTTADGVARVRKSKGKFAF----------LLESTMNEYIEQRKPCDTMKVGGNL--DSKGY 758

  Fly   550 GSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDC----SLFKTSQAEVDLEHFAPALF 610
            |...||||..|..:..|:|.....|:|.....||...:.:|    |..|...:.:.|.:.|...:
Mouse   759 GVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFY 823

  Fly   611 ----ALALAMVASALVF 623
                .|.|||:.:.:.|
Mouse   824 ILVGGLGLAMMVALIEF 840

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.