Protein Alignment Ir84a and GluRIB

DIOPT Version :9

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 130/633 - (20%)
• Similarity: 225/633 - (35%)
• Gaps: 179/633 - (28%)

  Fly   116 GVASEAGYFNNSLAWFILGSGRESLPVEQLIDQLLSGYRMGIDAD-ITVALRGPDNASMLFYDVY 179
            |:||.|...|.:..|.......:.          :|.|...::.: :|..::..|:...:.|.::
  Fly   402 GMASRALDCNTAKGWVNAWEHGDK----------ISRYLRKVEIEGLTGDIKFNDDGRRVNYTLH 456

  Fly   180 RISRQANTPLIIEKKGLWTHSGGYQKFGNFKNTWVIRRRNFL----NVTLIGSTVLTE-----KP 235
            .:....|:.::  |...|....|.|..    |...:|.|..:    |.|.|.:|||.|     |.
  Fly   457 VVEMTVNSAMV--KVAEWNDDAGLQPL----NAKYVRLRPHVEFEKNRTYIVTTVLEEPYIMLKQ 515

  Fly   236 PGFGDMEYLADDKQLQQLDPMQRKTYQLFQLV--ERMFNLSLAISLTDKWG--ELLDNGSWSGVM 296
            ..||:        :|...:..:.....|..|:  |...|..|.:.....:|  :...:|.|.|::
  Fly   516 VAFGE--------KLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDGMV 572

  Fly   297 GQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNI-----FFEPLSNQV 356
            |::..:|||.|:..:....:|:..:.:|....:..|..:.:.|    :|..     |..|||.::
  Fly   573 GELVRKEADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKP----VKQTPGVFSFMNPLSQEI 633

  Fly   357 WWCVLALVTGSTILLLF------------------------HVRLERMLSNME------------ 385
            |..|:....|.:|:|.|                        |...|: |:|.:
  Fly   634 WVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQ-LANQQPPGIIGGAPLPA 697

  Fly   386 -------------------------------------NRFSF---VWFTMLETYLQQG----PAN 406
                                                 |.||.   .||: |..::|||    |
  Fly   698 PPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFS-LAAFMQQGCDLSP-- 759

  Fly   407 EIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYDSNLAIGMENISYNFP 471
               |..|.|:..:....|:.:|:..|.|.:...|..|...:.:|    ...:||:..| :.|...
  Fly   760 ---RSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPIN----SPEDLAMQTE-VQYGTL 816

  Fly   472 IFTNTSNQLVRDVYVKKICKSGEHNIM-------------SLQQGAERI--IQGRFAFHTAIDRM 521
            :..:|.:...|.       :.|.||.|             :..:|.:|:  .:|::|
  Fly   817 LHGSTWDFFRRS-------QIGLHNKMWEYMNSRKHVFVPTYDEGIKRVRNSKGKYA-------- 866

  Fly   522 YRLLLELQMDE----AEFCDLQEVMFNLPYDS-GSVMPKGSPWREHLAHALLHFRATGLLQYNDK 581
              ||:|...:|    .|.||..:|..||.... |...|.||..::.:..|:|..:..|.|.....
  Fly   867 --LLVESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRN 929

  Fly   582 KWMVRRPDCSLFK---TSQAEVDLEHFAPALFALALAMVASALVFLLE 626
            ||...:.:||..|   ||.:|:.|.:.|...:.|...::.|..|.:||
  Fly   930 KWWYEKAECSTHKDGETSHSELSLSNVAGIFYILIGGLLVSVFVAILE 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	96/474 (20%)
		Lig_chan	355..602	CDD:278489	70/349 (20%)
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	14/87 (16%)
		ANF_receptor	55..461	CDD:279440	11/68 (16%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	98/481 (20%)
		Lig_chan	632..967	CDD:278489	73/363 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940