Protein Alignment Ir84a and gria4a

DIOPT Version :9

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_999971.1
• Gene: gria4a / 407735
• ZFINID: ZDB-GENE-020125-7
• Length: 898
• Species: Danio rerio
• Alignment Length: 613
• Identity: 140/613 - (22%)
• Similarity: 246/613 - (40%)
• Gaps: 151/613 - (24%)

  Fly    93 YGSPRT--AVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFILGSGRESLPVEQLIDQLLSGYRM 155
            |.|..|  .|||:......:|||...: |..|...:.||       ..:.|           :..
Zfish   291 YTSSLTYDGVLVMAEAFRNLRRQKIDI-SRRGNAGDCLA-------NPAAP-----------WNQ 336

  Fly   156 GIDADIT---VALRGPDNASMLFYDVYRISRQAN-TPLIIEKKGLWTHSGGYQKFGNFKN-TWVI 215
            |||.:.|   |.::|  ....:.:|.|  .|:.| |..:.|.|     |.|.:|.|.:.: ..::
Zfish   337 GIDMERTLKQVRIQG--LTGNIQFDHY--GRRVNYTMDVFELK-----SNGPRKIGYWNDLDKLV 392

  Fly   216 RRRNFL---------NVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQRKTYQLFQLVERM- 270
            ..:|.|         |.|:|.:|:: |.|       |:           |.:|.:::::..|:.
Zfish   393 LVQNELSMGNDSAMENRTVIVTTIM-EGP-------YV-----------MLKKNWEMYEGNEQFE 438

  Fly   271 ---------------FNLSLAISLTDKWGEL-LDNGSWSGVMGQVTSREADFAVCPIRFVLDRQP 319
                           ....::|.|..|:|.. .:...|:|::|::...:|:.||.|:...|.|:.
Zfish   439 GYCVDLASEVAKHIGIKYKISIVLDGKYGARDPETKIWNGMVGELVYGKAEIAVAPLAITLVREE 503

  Fly   320 YVQYSAVLHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLERMLSN 383
            .:.:|....:..|..:.:.|::|..... |.:||:.::|.|::....|.:::|....|......:
Zfish   504 VIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH 568

  Fly   384 MENR------------------FSFVWFTMLETYLQQG----PANEIFRLFSTRLLISLSCIFSF 426
            .|..                  |:.:||: |..::|||    |     |..|.|::..:...|:.
Zfish   569 TEEPEEGSDGPPSDQPPNEFGIFNSLWFS-LGAFMQQGCDFTP-----RSLSGRIVGGVWWFFTL 627

  Fly   427 MLMQFYGAFIVGSLLSESARSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQLVR----DVYVK 487
            :::..|.|.:...|..|  |.:..:::..|  ||...| |:|. .:.:.::.:..|    .||.|
Zfish   628 IIISSYTANLAAFLTVE--RMVSPIESAED--LAKQTE-IAYG-TLDSGSTKEFFRRSKIAVYEK 686

  Fly   488 --KICKSGEHNIM--SLQQGAERI--IQGRFAFHTAIDRMYRLLLELQMDE----AEFCDLQEVM 542
              ...||.|..:.  :..:|..|:  .:|::||          |||..|:|    .:.||..:|.
Zfish   687 MWSYMKSAEPTVFTKTTAEGVARVRKSKGKYAF----------LLESTMNEYTEQRKPCDTMKVG 741

  Fly   543 FNLPYDS---GSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDC------SLFKTSQA 598
            .||  ||   |...||||.....:..|:|.....|:|.....||...:.:|      |..|:|||
Zfish   742 GNL--DSKGYGVATPKGSQLGTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKSSQA 804

  Fly   599 EVDLEHFAPALFALALAMVASALVFLLE 626
             :.|.:.|...:.|...:..:.||.|:|
Zfish   805 -LSLSNVAGVFYILVGGLGLAMLVALVE 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020	6/20 (30%)
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	92/417 (22%)
		Lig_chan	355..602	CDD:278489	70/291 (24%)
gria4a	NP_999971.1	PBP1_iGluR_AMPA_GluR4	23..393	CDD:107383	31/129 (24%)
		ANF_receptor	34..375	CDD:279440	26/106 (25%)
		PBP2_iGluR_AMPA_GluR4	408..790	CDD:270445	94/424 (22%)
		Lig_chan	540..821	CDD:278489	73/305 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940