Protein Alignment Ir84a and Nmdar1

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 749
• Identity: 157/749 - (20%)
• Similarity: 295/749 - (39%)
• Gaps: 190/749 - (25%)

  Fly    36 AAFED------FLRS------------EHLSH-----VLVVRGDDADG----------------D 61
            |||.|      |||:            |.|||     |:::...|.||                |
  Fly   139 AAFSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSDTDGRAILGRFQTTSQTYYDD 203

  Fly    62 WKIECHQKLLANYRVQFYRPEMSANFEDL-----------MFYGSPRTAVLVLNSE--------- 106
            ..:....:|:..     :.|::.:..|.|           :.|.|...|.::....
  Fly   204 VDVRATVELIVE-----FEPKLESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEG 263

  Fly   107 HV-LVRRQ----------VFGVA-----SEAGYFNNSLAWFILGSG-RESLPVEQLID------- 147
            || :|..|          |.|:.     |:.|:..:|:  ::|.|. :|.:..|.:.:
  Fly   264 HVWIVTEQALFSNNTPDGVLGLQLEHAHSDKGHIRDSV--YVLASAIKEMISNETIAEAPKDCGD 326

  Fly   148 ---QLLSGYRM-------GIDADITVALRGPDNASMLF--YDVYRISRQANTPLIIEKKGLWTHS 200
               ...||.|:       .|..: |..:...||...::  |||..|..|....::    |.:::.
  Fly   327 SAVNWESGKRLFQYLKSRNITGE-TGQVAFDDNGDRIYAGYDVINIREQQKKHVV----GKFSYD 386

  Fly   201 GGYQK----FGNFKNTWVIRRR----NFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQ 257
            ....|    ..:.:..|..::|    ..:..|.:....:.|||  |..:..:.||:  .:.:|.:
  Fly   387 SMRAKMRMRINDSEIIWPGKQRRKPEGIMIPTHLRLLTIEEKP--FVYVRRMGDDE--FRCEPDE 447

  Fly   258 R-----------------KTY---QLFQLVERM-FNLSLAISLTDKWGE-LLDNGS--------W 292
            |                 :.|   .|.:|.:|: |...||:|...::|. :|.|.:        |
  Fly   448 RPCPLFNNSDATANEFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEW 512

  Fly   293 SGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNIFFEPLSNQVW 357
            :|::|::.:..||..|.|:....:|..|:::|.....|.|..|.:.|.||.....|.:|.||.:|
  Fly   513 TGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLW 577

  Fly   358 WCVLALVTGSTILLLFHV----------RLERMLSNME---NRFSFVWF---TMLETYLQQGPAN 406
              :|.:|:...:.|:.::          :|....||.|   |..|.|||   .:|.:.:.:|..
  Fly   578 --ILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTP- 639

  Fly   407 EIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYDSNLAIGMENISYNFP 471
               |.||.|:|..:...|:.:::..|.|.:...|:.|  |....|..:.|:.|...|||::....
  Fly   640 ---RSFSARVLGMVWAGFAMIIVASYTANLAAFLVLE--RPKTKLSGINDARLRNTMENLTCATV 699

  Fly   472 IFTNTSNQLVRDVYVKKICKSGE-HNIMSLQQGAERIIQGR-FAFHTAIDRMYRLLLELQMDEAE 534
            ..::......|.|.:..:.::.| :|..:.:|..:.:.:|: .||.....|       |:.:.::
  Fly   700 KGSSVDMYFRRQVELSNMYRTMEANNYATAEQAIQDVKKGKLMAFIWDSSR-------LEYEASK 757

  Fly   535 FCDL---QEVMFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVR---RPDCSLF 593
            .|:|   .|:.....|..|  :.|||||.:.:..|:|.|..:|.::..||:|:..   :.:|.||
  Fly   758 DCELVTAGELFGRSGYGIG--LQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCELF 820

  Fly   594 KTSQAEVDLEHFAPALFALALAMVASALVFLLEL 627
            :.:...:.|::.|.....:.:.:.....:.::|:
  Fly   821 EKTPNTLGLKNMAGVFILVGVGIAGGVGLIIIEV 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	14/94 (15%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	22/81 (27%)
		Lig_chan	353..602	CDD:459656	64/272 (24%)
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	51/277 (18%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	99/421 (24%)
		CaM_bdg_C0	854..882	CDD:402271	0/1 (0%)