Protein Alignment Ir84a and gria1b

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_991293.1
• Gene: gria1b / 403044
• ZFINID: ZDB-GENE-020125-2
• Length: 917
• Species: Danio rerio
• Alignment Length: 755
• Identity: 154/755 - (20%)
• Similarity: 282/755 - (37%)
• Gaps: 205/755 - (27%)

  Fly     5 QVKVISWPLIILTAFLRVLQ---------------IESINTNFLELAAFEDFLRSEHLSHVLVVR 54
            ||..|::..:...|||:.:|               :|.:|:....:||.:..|::.|  ::|...
Zfish   170 QVTSINFDTLTEAAFLKAIQDLDNKKEFKIILDCELERLNSILNLIAAQKKNLKNYH--YILANL 232

  Fly    55 G-------DDADGDWKIECHQKLLANYRVQFYRPEMSANFEDLMFYG-----SPR-----TAVLV 102
            |       :...|...:...|  |.||.    .|.:|...:|.:.:.     ||:     |..|.
Zfish   233 GFLDLNLTEFRKGGANVTGFQ--LMNYT----NPTVSRTIQDWLEFDSKDLKSPKRRLKYTGALT 291

  Fly   103 LNSEHVL------VRRQVFGVASEAGYFNNSLA-----WFILGSGRESLPVEQLIDQL----LSG 152
            .:...|:      :|:|...: |..|.....||     |   |.|   :.:::.:.|:    |:|
Zfish   292 YDGVTVMATAFQNLRKQRIDI-SRRGNAGECLANPPAPW---GQG---IDIQRALQQVQFEGLTG 349

  Fly   153 Y----RMGIDADITVALR--GPDNASMLFYDVYRISRQANTPLIIEKKGLWTHSGGYQKFGNFKN 211
            :    ..|...:.||::.  ||...                    :|.|.|.....|.....:.|
Zfish   350 HVQFNDKGHRTNFTVSVMEFGPSGP--------------------KKVGYWNQREKYVSTATYSN 394

  Fly   212 ----TWVIRRRNFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQL---DPMQRKTYQLFQLVER 269
                |:.::.|.::..|::      |.|       |:...|..:||   |..:....:|...:.:
Zfish   395 MLNETFGLQNRTYVVTTIL------EAP-------YVMLKKNHEQLVGNDKYEGYCVELAAEIAK 446

  Fly   270 MFNLSLAISLT--DKWGEL-LDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQN 331
            ....|..:.|.  .|:|.. .:...|:|::|::...:||.||.|:...|.|:..:.:|....:..
Zfish   447 HVGYSYRLELVGDGKYGARDAETMMWNGMVGELVYGKADVAVAPLTITLVREEVIDFSKPFMSLG 511

  Fly   332 IHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLL---------FHVRLERMLSNMEN 386
            |..:.:.|.:|..... |.:||:.::|.|::....|.:::|.         :|...|...::.:|
Zfish   512 ISIMIKKPTKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHADDEEETADQQN 576

  Fly   387 R-----------------------------------FSFVWFTMLETYLQQG----PANEIFRLF 412
            :                                   |:.:||: |..::|||    |     |..
Zfish   577 QNQPPSPEPNQSPNQSQNQREEKQEKQPEHTNEFGIFNSLWFS-LGAFMQQGCDISP-----RSL 635

  Fly   413 STRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYD----SNLAIGMENISYNFPIF 473
            |.|::..:...|:.:::..|.|.:...|..|  |.:..:::..|    :.:|.|..:.......|
Zfish   636 SGRIVGGVWWFFTLIIISSYTANLAAFLTVE--RMVSPIESAEDLAKQTEIAYGTLDGGSTKEFF 698

  Fly   474 TNTSNQLVRDVYVKKICKSGEHNIM--SLQQGAERI--IQGRFAFHTAIDRMYRLLLELQMDE-- 532
            ..:...:...::  ...||.|..:.  :..:|..|:  .:|::|:          |||..|:|
Zfish   699 RRSKIAVFEKMW--SYMKSAEPTVFVKTTDEGVVRVRKSKGKYAY----------LLESTMNEYI 751

  Fly   533 --AEFCDLQEVMFNLPYDS---GSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDC-- 590
              .:.||..:|..||  ||   |...||||..|..:..|:|.....|||.....||...:.:|
Zfish   752 EQRKPCDTMKVGGNL--DSKGYGVATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 814

  Fly   591 ----SLFKTSQAEVDLEHFAPALFALALAMVASALVFLLE 626
                |..|||  .:.|.:.|...:.|...:..:.||.|:|
Zfish   815 GGGDSKDKTS--ALSLSNVAGVFYILIGGLGLAMLVALVE 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	14/80 (18%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	19/74 (26%)
		Lig_chan	353..602	CDD:459656	65/317 (21%)
gria1b	NP_991293.1	PBP1_iGluR_AMPA_GluR1	26..390	CDD:380613	49/254 (19%)
		PBP2_iGluR_AMPA_GluR1	404..812	CDD:270447	91/442 (21%)