back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir84a and GluRIIA

DIOPT Version :9

Sequence 1:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_523484.2	Gene:	GluRIIA / 33788	FlyBaseID:	FBgn0004620	Length:	907	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	101/495 - (20%)
Similarity:	172/495 - (34%)	Gaps:	173/495 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 DVYRISRQANTPLIIEKKGLWTHSGGYQKFGNFKNTWVIRRRNFLNVTL--IGSTVLTEKPPGFG 239
            ::|:       |.:.|...:||...|.:|             ..||:.|  .|:|      ..|.
  Fly   385 EIYK-------PTVNEPMMVWTPDNGIKK-------------RLLNLELESAGTT------QDFS 423

  Fly   240 DMEYLADDKQLQQLDPMQRKTYQL--------FQLVERMFNL-------SLAISLTDKWGELLD- 288
            :                |||.|.:        |.:.|...|.       ..|:.|..|..||::
  Fly   424 E----------------QRKVYTVVTHYEEPYFMMKEDHENFRGREKYEGYAVDLISKLSELMEF 472

  Fly   289 -------NGS---------WSGVMGQVTSREADFAVCPI------RFVLD-RQPYVQYS-AVLHT 329
                   ||:         |.|::.::....|...||.:      |.|:| ..|::|.. ::||
  Fly   473 DYEFMIVNGNGKYNPETKQWDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILH- 536

  Fly   330 QNIHFLFRHPRRSHIKNIFFEPLSNQVWWCVLALVTGSTILLLFHVRLERM-------------- 380
                  ::.|.....:..|.||.:.:||   :.::....|:.|..|.:.|:
  Fly   537 ------YKSPPEPKNQFAFLEPFAVEVW---IYMIFAQLIMTLAFVFIARLSYREWLPPNPAIQD 592

  Fly   381 ---LSNMENRFSFVWFTMLETYLQQGPANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLS 442
               |.|:.|..:..|. |:.:.:||| .:.:.|....|:|..:...|:.|::..|.|.:...|.|
  Fly   593 PDELENIWNVNNSTWL-MVGSIMQQG-CDILPRGPHMRILTGMWWFFALMMLSTYTANLAAFLTS 655

  Fly   443 ES-ARSIVNLQALYD-------------SNLAIGMENIS-----------YNFPIFTNTSNQLVR 482
            .. ..||.:||.|.:             ::|.....|.:           :|...||:|:.:.|.
  Fly   656 NKWQSSIKSLQDLIEQDKVHFGSMRGGSTSLFFSESNDTDYQRAWNQMKDFNPSAFTSTNKEGVA 720

  Fly   483 DVYVKKICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLE---LQMDEAEFCDLQEVMFN 544
            .|..:|                     |.:||          |:|   |..:....|||.::...
  Fly   721 RVRKEK---------------------GGYAF----------LMETTSLTYNIERNCDLTQIGEQ 754

  Fly   545 L-PYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKW 583
            : ....|..:|.||.:|.:|:.::|.....|.||....||
  Fly   755 IGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKW 794

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.