Protein Alignment Ir84a and gria4b

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_997917.2
• Gene: gria4b / 336069
• ZFINID: ZDB-GENE-030131-8013
• Length: 904
• Species: Danio rerio
• Alignment Length: 620
• Identity: 134/620 - (21%)
• Similarity: 246/620 - (39%)
• Gaps: 164/620 - (26%)

  Fly    93 YGSPRT--AVLVLNSEHVLVRRQVFGVASEAGYFNNSLA-----WFILGSGRESLPVEQLIDQLL 150
            |.|..|  .|:|:......:|||...: |..|...:.||     |      .:.:.:|:.:.|:
Zfish   296 YTSALTYDGVMVMAEAFRNLRRQKVDI-SRRGIAGDCLANPAAPW------NQGIDMERTLKQV- 352

  Fly   151 SGYRMGIDADITVALRGPDNASMLFYDVYRISRQAN-TPLIIEKKGLWTHSGGYQKFG--NFKNT 212
              :..|:..::.             :|.|  .|:.| |..:.|.|     |.|.::.|  |..:.
Zfish   353 --HLQGLTGNVQ-------------FDHY--GRRVNYTMDVFELK-----SNGPRRIGYWNDADK 395

  Fly   213 WVIRRRNFL---------NVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQRKTYQLFQLVE 268
            .|:.:.:.|         |.|:|.:|:: |.|       |:           |.:|.:::::..|
Zfish   396 LVLTQDHALLPNETSGMENRTVIVTTIM-EGP-------YV-----------MLKKNWEMYEGNE 441

  Fly   269 RM----------------FNLSLAISLTDKWGEL-LDNGSWSGVMGQVTSREADFAVCPIRFVLD 316
            :.                |...::|....|:|.. .:...|:|::|::...:|:.||.|:...|.
Zfish   442 QYEGYCVDLASEIAKHIGFKYKISIVPDGKYGARDPETKIWNGMVGELVYGKAEIAVAPLTITLV 506

  Fly   317 RQPYVQYSAVLHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLERM 380
            |:..:.:|....:..|..:.:.|::|..... |.:||:.::|.|::....|.:::|....|....
Zfish   507 REEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPY 571

  Fly   381 LSNMENR------------------FSFVWFTMLETYLQQG----PANEIFRLFSTRLLISLSCI 423
            ..:.|..                  |:.:||: |..::|||    |     |..|.|::..:...
Zfish   572 EWHTEEPEEGTDGLPSDQPPNEFGIFNSLWFS-LGAFMQQGCDISP-----RSLSGRIVGGVWWF 630

  Fly   424 FSFMLMQFYGAFIVGSLLSESARSIVNLQALYD----SNLAIGMENISYNFPIFTNTSNQLVR-- 482
            |:.:::..|.|.:...|..|  |.:..:::..|    :::|.|        .:.:.::.:..|
Zfish   631 FTLIIISSYTANLAAFLTVE--RMVSPIESAEDLAKQTDIAYG--------TLDSGSTKEFFRRS 685

  Fly   483 --DVYVK--KICKSGEHNIM--SLQQGAERI--IQGRFAFHTAIDRMYRLLLELQMDE----AEF 535
              .||.|  ...||.|..:.  :..:|..|:  .:|::||          |||..|:|    .:.
Zfish   686 KIAVYEKMWSYMKSAEPTVFTKTTAEGVARVRKSKGKYAF----------LLESTMNEYTEQRKP 740

  Fly   536 CDLQEVMFNLPYDS---GSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDC------S 591
            ||..:|..||  ||   |...||||..|..:..|:|.....|||.....||...:.:|      .
Zfish   741 CDTMKVGGNL--DSKGYGVATPKGSQLRSAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGGE 803

  Fly   592 LFKTSQAEVDLEHFAPALFALALAMVASALVFLLE 626
            ..|:||| :.|.:.|...:.|...:..:.||.|:|
Zfish   804 KDKSSQA-LSLSNVAGVFYILVGGLGLAMLVALIE 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	5/20 (25%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	18/74 (24%)
		Lig_chan	353..602	CDD:459656	68/297 (23%)
gria4b	NP_997917.2	Periplasmic_Binding_Protein_type1	28..400	CDD:471960	28/133 (21%)
		PBP2_iGluR_AMPA_GluR4	414..793	CDD:270445	93/425 (22%)
		Lig_chan	546..826	CDD:459656	71/308 (23%)