Protein Alignment Ir84a and GluRIIE

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 146/747 - (19%)
• Similarity: 260/747 - (34%)
• Gaps: 187/747 - (25%)

  Fly    30 TNFLELAAFEDFLRSEHLSHVLVVRGDDADGDWKIECHQKLLANYRVQFYRPEMSANFEDLMFYG 94
            |.|:.|....::|..  |:.:..:.|........:....:|..||:....|...|.: ..::..|
  Fly   159 TRFIFLYESAEYLNI--LNELTTMLGKSGTVITVLRYDMQLNGNYKQVLRRVRKSVD-NRIVVVG 220

  Fly    95 SPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFILGS------------------------ 135
            |..|....||.            |.:.|..|.... :|:|:
  Fly   221 SSETMPEFLNQ------------AQQVGIINEDYK-YIIGNLDFHSFDLEEYKYSEANITGLRLF 272

  Fly   136 GRESLPVEQLIDQLLSGYRMGID------ADITVALRGPDNASMLFYDVYRISRQA--NTPLIIE 192
            ..|.:.|::|:.:|  ||....|      ..|||.:       .|.||..::..|.  |.|....
  Fly   273 SPEKMAVKELLMKL--GYPTDQDEFRNGSCPITVEM-------ALTYDAVQLFAQTLKNLPFKPM 328

  Fly   193 KKGLWTHSGGYQKFG-NFKNTWVIRRRNFLNVTLIGS-------------TVLTEKPPGFGDMEY 243
            .:.....:...:..| :|||  .:|.....:..|.|.             .|:..:|.|...:..
  Fly   329 PQNCSQRTESVRDDGSSFKN--YMRTLRLTDRLLTGPIYFEGNVRKGYHLDVIELQPSGIVKVGT 391

  Fly   244 LADDKQL--QQLDP-----------MQRKTYQLF---------QLVERM-----------FNLSL 275
            ..:|:|.  |:|.|           :..||:.:.         ||||..           :.:.|
  Fly   392 WDEDRQYRPQRLAPTTAQFDSVDNSLANKTFIILLSVPNKPYAQLVETYKQLEGNSQYEGYGVDL 456

  Fly   276 AISLTDKWGELL-------DNGSW-------SGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAV 326
            ...|.||.|...       |.||:       :|::.::.:..||.|:..:....:|:..:.::..
  Fly   457 IKELADKLGFNFTFVNGGNDYGSYNKSTNESTGMLREIMTGRADLAITDLTITSEREQALDFTIP 521

  Fly   327 LHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLE-----------R 379
            .....|..|:..|:::..:.. |.:|.|.:|||.:.....|.::......||.           .
  Fly   522 FMNLGIAILYLKPQKATPELFTFMDPFSEEVWWFLGFSFLGVSLSFFILGRLSPSEWDNPYPCIE 586

  Fly   380 MLSNMENRFSF---VWFTMLETYLQQGPANEIF-RLFSTRLLISLSCIFSFMLMQFYGAFIVGSL 440
            ....:||:|:.   :||| ....||||  :||. :..|||.:.|....|:.:::..|.|.:...|
  Fly   587 EPEELENQFTLGNSIWFT-TGALLQQG--SEIGPKALSTRTVASFWWFFTLIVVSSYTANLAAFL 648

  Fly   441 LSESARSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQLV--RDVYVKKICKSGEHNIMSL--- 500
            ..|..:|::|..    .:||...:.:.|......:|.|..:  .:...||:.|....|...|
  Fly   649 TIEKPQSLINSV----DDLADNKDGVVYGAKKTGSTRNFFMTSAEERYKKMNKFMSENPQYLTED 709

  Fly   501 -QQGAERIIQGRFAFHTAIDRMYRLLLE---LQMDEAEFCDLQEVMFNLPYDS-GSVMPKGSPWR 560
             .:|..|:         ..:..|..|:|   ::.:....|:|:::...|.... |..|.|..|.|
  Fly   710 NMEGVNRV---------KTNTHYAFLMESTSIEYNTKRECNLKKIGDALDEKGYGIAMRKDWPHR 765

  Fly   561 EHLAHALLHFRATGLLQYNDKKWMVR-----------RPDCSLFKTSQAEVDLEHFAPALFALAL 614
            ....:|||..:..|:|:....||...           .||.:       .:|:.:.....|.|.:
  Fly   766 GKFNNALLELQEQGVLEKMKNKWWNEVGTGICATKEDAPDAT-------PLDMNNLEGVFFVLLV 823

  Fly   615 AM-------VASALVFLLELFLHWLPDFRRRL 639
            ..       :.|.::|:::...|:....|..|
  Fly   824 GSCCALLYGIISWVLFVMKKAHHYRVPLRDAL 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	11/57 (19%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	16/87 (18%)
		Lig_chan	353..602	CDD:459656	62/284 (22%)
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	40..402	CDD:380605	49/269 (18%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	84/386 (22%)
		Lig_chan	551..824	CDD:459656	64/295 (22%)