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Protein Alignment Ir84a and Gria2

DIOPT Version :9

Sequence 1:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	665	Identity:	139/665 - (20%)
Similarity:	255/665 - (38%)	Gaps:	151/665 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 HVLVVRGDDADGD-WKIECHQKLLANYRVQFYRPEMSANF-------EDLMFYGS-----PRTAV 100
            |.::......||| .||:.....::.:::..|...:.:.|       |:..:.|:     ..|:.
  Rat   234 HYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSA 298

  Fly   101 LVLNSEHVL------VRRQVFGVA--SEAG--YFNNSLAWFILGSGRESLPVEQLIDQL----LS 151
            |..::..|:      :|:|...::  ..||  ..|.::.|   |.|.|   :|:.:.|:    ||
  Rat   299 LTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPW---GQGVE---IERALKQVQVEGLS 357

  Fly   152 GYRMGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTH-----------SGGYQK 205
            |           .::...|...:.|.:..:..:.|.|   .|.|.|:.           ..|...
  Rat   358 G-----------NIKFDQNGKRINYTINIMELKTNGP---RKIGYWSEVDKMVVTLTELPSGNDT 408

  Fly   206 FGNFKNTWVIRRRNFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQRKTYQLFQLVERM 270
            .|            ..|.|::.:|:| |.|       |:...|..:.|:..:|.......|...:
  Rat   409 SG------------LENKTVVVTTIL-ESP-------YVMMKKNHEMLEGNERYEGYCVDLAAEI 453

  Fly   271 -----FNLSLAISLTDKWGEL-LDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHT 329
                 |...|.|....|:|.. .|...|:|::|::...:||.|:.|:...|.|:..:.:|....:
  Rat   454 AKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMS 518

  Fly   330 QNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRL--------------ER 379
            ..|..:.:.|::|..... |.:||:.::|.|::....|.:::|....|.              |.
  Rat   519 LGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRET 583

  Fly   380 MLSNMENRFSF---VWFTMLETYLQQG----PANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIV 437
            ..|...|.|..   :||: |..:::||    |     |..|.|::..:...|:.:::..|.|.:.
  Rat   584 QSSESTNEFGIFNSLWFS-LGAFMRQGCDISP-----RSLSGRIVGGVWWFFTLIIISSYTANLA 642

  Fly   438 GSLLSESARSIVNLQALYD----SNLAIGMENISYNFPIFTNTSNQLVRDVYVKKICKSGEHNIM 498
            ..|..|  |.:..:::..|    :.:|.|..:.......|..:...:...::.  ..:|.|.::.
  Rat   643 AFLTVE--RMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWT--YMRSAEPSVF 703

  Fly   499 --SLQQGAERI--IQGRFAFHTAIDRMYRLLLELQMDE----AEFCDLQEVMFNLPYDS---GSV 552
              :..:|..|:  .:|::|:          |||..|:|    .:.||..:|..||  ||   |..
  Rat   704 VRTTAEGVARVRKSKGKYAY----------LLESTMNEYIEQRKPCDTMKVGGNL--DSKGYGIA 756

  Fly   553 MPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDC------SLFKTSQAEVDLEHFAPALFA 611
            .||||.....:..|:|.....|||.....||...:.:|      |..|||  .:.|.:.|...:.
  Rat   757 TPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTS--ALSLSNVAGVFYI 819

  Fly   612 LALAMVASALVFLLE 626
            |...:..:.||.|:|
  Rat   820 LVGGLGLAMLVALIE 834

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.