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Protein Alignment Ir84a and GRIK1

DIOPT Version :9

Sequence 1:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_001317923.1	Gene:	GRIK1 / 2897	HGNCID:	4579	Length:	949	Species:	Homo sapiens

Alignment Length:	516	Identity:	121/516 - (23%)
Similarity:	202/516 - (39%)	Gaps:	81/516 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 SGYRMGIDADITVALR--GPDNA----SMLFYDVYRISRQANTPLIIEKKGLWTHSGGYQKFGNF 209
            :|.|...|.|| ::|:  |.:.|    |...|.|::            |.|:|..:.|.....:.
Human   382 NGLRKDFDLDI-ISLKEEGTEKAAGEVSKHLYKVWK------------KIGIWNSNSGLNMTDSN 433

  Fly   210 KNTWVIRRRNFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQRKTYQLFQLVERMFNLS 274
            |:.......:..|.|||.:|:| |:|    .:.|...||.|...|..:.....|.:.:..:....
Human   434 KDKSSNITDSLANRTLIVTTIL-EEP----YVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFI 493

  Fly   275 LAISLT--DKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFR 337
            ..:.|.  .|:|...|.|.|:|::.::....||.||.|:.....|:..:.:|....|..|..|:|
Human   494 YDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYR 558

  Fly   338 HPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLERM-----------LSNMENRFSF 390
            .|..::.... |..|||..:|..||....|.:.:|....|....           ...:||.|:.
Human   559 KPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTL 623

  Fly   391 V---WFTMLETYLQQGPANEIF-RLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNL 451
            :   ||. :...:|||  :|:. :..|||::..:...|:.:::..|.|.:...|..|...|.:
Human   624 LNSFWFG-VGALMQQG--SELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPI-- 683

  Fly   452 QALYDS--NLAIGMENISYNFPIFTNTSNQLVRD----VYVKKICKSGEHNI---MSLQQGAERI 507
                ||  :|| ....|.|.          .|||    .:.||...|....:   ||.:|....:
Human   684 ----DSADDLA-KQTKIEYG----------AVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALV 733

  Fly   508 IQGRFAFHTAIDRMYRLLLE---LQMDEAEFCDLQEV---MFNLPYDSGSVMPKGSPWREHLAHA 566
            ..........:...|.||:|   ::......|:|.::   :.:..|..|:  |.|||:|:.:..|
Human   734 RNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGT--PIGSPYRDKITIA 796

  Fly   567 LLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAE-VDLEHFAPALFALALAMVASALVFLLE 626
            :|..:..|.|....:||. |...|......:|. :.:|:.......||..:|.|..|.:.|
Human   797 ILQLQEEGKLHMMKEKWW-RGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGE 856

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.