Protein Alignment Ir84a and Grin2d

DIOPT Version :9

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_038951440.1
• Gene: Grin2d / 24412
• RGDID: 2740
• Length: 1334
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 128/666 - (19%)
• Similarity: 232/666 - (34%)
• Gaps: 187/666 - (28%)

  Fly   114 VFGVASEAGYFNNSLAWFIL-----GSGRESLPVEQLIDQLL---------------SGYR---- 154
            ||..|.|||.......||::     |.|...:|.|.|   ||               :|:|
  Rat   253 VFRAAEEAGLTGPGYVWFMVGPQLAGGGGSGVPGEPL---LLPGGSPLPAGLFAVRSAGWRDDLA 314

  Fly   155 MGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTHSGG--YQKFGNFKNTWVIRR 217
            ..:.|.:.|..||   |..|..| |....:.......:.:   ||.|.  ::.|.|.  ||..|.
  Rat   315 RRVAAGVAVVARG---AQALLRD-YGFLPELGHDCRTQNR---THRGESLHRYFMNI--TWDNRD 370

  Fly   218 RNF-------------LNVT------LIGS----TVLTEKP--PGFGDMEYLADDKQ-------- 249
            .:|             :::|      ::||    |:..:.|  ..:|......||.|
  Rat   371 YSFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLE 435

  Fly   250 ------LQQLDPMQ--------------RKTYQ----------------LFQLVERM-----FNL 273
                  ::..||:.              .:|:.                ...:::|:     |:.
  Rat   436 ERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSY 500

  Fly   274 SLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRH 338
            .|.:....|.|:.:| |.|:|::|:|..:.||.|:..:....:|...|.:|.......|..:...
  Rat   501 DLYLVTNGKHGKKID-GVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVAR 564

  Fly   339 PRRSHIKNIFF-----------EPLSNQVW--WCVLALVTGSTILLLFH----VRLERMLSNME- 385
            ...:...:.|.           ||.|..||  ..|:.|...:..:.:|.    |...|.|:..:
  Rat   565 SNGTVSPSAFLAFAWLTPPMSPEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKR 629

  Fly   386 ---NRFSF---VWFTMLETYLQQGPANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSE- 443
               :.|:.   :|......:....|. |..|..::::::.:...|:.:.:..|.|.:...::.|
  Rat   630 PGGSTFTIGKSIWLLWALVFNNSVPV-ENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEE 693

  Fly   444 --------SARSIVNLQALYDSNLAIGM-------ENISYNFPIFTNTSNQLVRDVYVKKICKSG 493
                    |.|.....|..|.. |..|.       :||..|:|   :..:.:||
  Rat   694 YVDTVSGLSDRKFQRPQEQYPP-LKFGTVPNGSTEKNIRSNYP---DMHSYMVR----------- 743

  Fly   494 EHNIMSLQQGAERIIQGR---FAFHTAIDRMYRLLLELQMDEAEFCDL-----QEVMFNLPYDSG 550
             :|...:::...::..|:   |.:..|:       |.....:.|.|.|     .:|.....|  |
  Rat   744 -YNQPRVEEALTQLKAGKLDAFIYDAAV-------LNYMARKDEGCKLVTIGSGKVFATTGY--G 798

  Fly   551 SVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAEVDLEHFAPALFALALA 615
            ..:.|||.|:..:..|||.|.....::..::.|:.........:...:::|:::.|...:.|.:|
  Rat   799 IALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGICHNDKIEVMSSKLDIDNMAGVFYMLLVA 863

  Fly   616 MVASALVFLLELFLHW 631
            |..|.|||..|..::|
  Rat   864 MGLSLLVFAWEHLVYW 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	82/469 (17%)
		Lig_chan	355..602	CDD:278489	49/283 (17%)
Grin2d	XP_038951440.1	PBP1_iGluR_NMDA_NR2	46..410	CDD:380601	38/168 (23%)
		PBP2_iGluR_NMDA_Nr2	427..838	CDD:270436	75/437 (17%)
		PHA03307	<1125..>1312	CDD:223039

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350045
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930