Protein Alignment Ir84a and Grin2c

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_017452477.1
• Gene: Grin2c / 24411
• RGDID: 2739
• Length: 1250
• Species: Rattus norvegicus
• Alignment Length: 791
• Identity: 146/791 - (18%)
• Similarity: 261/791 - (32%)
• Gaps: 250/791 - (31%)

  Fly    14 IILT------AFLRV-------LQIESINTNFLELAAFEDFLRSEHLSHVLVVRGDDADGDWKIE 65
            ::||      |||::       ||:........:.:||. .:.|.|..|.|.:.|..|..|
  Rat   141 VVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFA-VITSLHPGHALFLEGVRAVAD---- 200

  Fly    66 CHQKLLANYRVQFYRPEMSANFEDLMFY----GSPRTAVLVLNSEHVLVRRQV------------ 114
                  |:|        :|....|::..    |.||.     .::.:|  |||
  Rat   201 ------ASY--------LSWRLLDVLTLELGPGGPRA-----RTQRLL--RQVDAPVLVAYCSRE 244

  Fly   115 -----FGVASEAGYFNNSLAWFI----LGS---GRESLPVEQLIDQLLSGYRMGIDADITVALRG 167
                 |..|::||.......|.:    |||   ...:.|| .||..:...:|:.:...:.
  Rat   245 EAEVLFAEAAQAGLVGPGHVWLVPNLALGSTDAPPAAFPV-GLISVVTESWRLSLRQKVR----- 303

  Fly   168 PDNASMLFYDVYRISRQANT--------------------------------------------- 187
             |..::|....:...||..|
  Rat   304 -DGVAILALGAHSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDFSFSPGGYLV 367

  Fly   188 -PLII----------EKKGLWTHSGGYQKFGNFKNTW---------VIRRRNFLNVTLIGST-VL 231
             |.::          |..|.|.|...|.|:    ..|         |:..|:....||.... |:
  Rat   368 RPTMVVIALNRHRLWEMVGRWDHGVLYMKY----PVWPRYSTSLQPVVDSRHLTVATLEERPFVI 428

  Fly   232 TEKP-PGFGDMEYLADDKQLQQLDPMQRKTYQLF------------------QLVERM-----FN 272
            .|.| ||.|..        :....|.:|::...|                  .:::::     |:
  Rat   429 VESPDPGTGGC--------VPNTVPCRRQSNHTFSSGDLTPYTKLCCKGFCIDILKKLAKVVKFS 485

  Fly   273 LSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFR 337
            ..|.:....|.|:.: .|.|:|::|:|..:.||.|:..:....:|...:.:|.......|..:..
  Rat   486 YDLYLVTNGKHGKRV-RGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVS 549

  Fly   338 HPRRSHIKNIFFEPLSNQVWWCVLALVTGSTILLLFHVRLERMLSNMENRFSFVWFTMLETYLQQ 402
            ....:...:.|.||.|..||  |:..|...|::.:             ..|.|.:|:.: :|.|.
  Rat   550 RSNGTVSPSAFLEPYSPAVW--VMMFVMCLTVVAI-------------TVFMFEYFSPV-SYNQN 598

  Fly   403 --------GPA----NEIFRLF----------------STRLLISLSCIFSFMLMQFYGAFIVGS 439
                    ||:    ..::.|:                ::::::.:...|:.:.:..|.|.:...
  Rat   599 LTKGKKPGGPSFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAF 663

  Fly   440 LLSESARSIVNLQALYDSNLAIGMENI-SYNFPIFTNTSNQL-----VRDVY---VKKICKSGEH 495
            ::.|  :.|..:..|.|.......:.. .:.|....|.|.:.     .||::   ||...:|.|.
  Rat   664 MIQE--QYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVED 726

  Fly   496 NIMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDEAEFCDL-----QEVMFNLPYDSGSVMPK 555
            .:.||:.|.    ...|.:..|:       |.....:.|.|.|     .:|.....|  |..|.|
  Rat   727 ALTSLKMGK----LDAFIYDAAV-------LNYMAGKDEGCKLVTIGSGKVFATTGY--GIAMQK 778

  Fly   556 GSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAEVDLEHFAPALFALALAMVASA 620
            .|.|:..:..|||.....|..|..:..|:.........:...:::|:::.|...:.|.:||..:.
  Rat   779 DSHWKRAIDLALLQLLGDGETQKLETVWLSGICQNEKNEVMSSKLDIDNMAGVFYMLLVAMGLAL 843

  Fly   621 LVFLLELFLHW 631
            |||..|..::|
  Rat   844 LVFAWEHLVYW 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	11/61 (18%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	17/72 (24%)
		Lig_chan	353..602	CDD:459656	52/290 (18%)
Grin2c	XP_017452477.1	PBP1_iGluR_NMDA_NR2	41..397	CDD:380601	51/288 (18%)
		PBP2_iGluR_NMDA_Nr2	413..813	CDD:270436	82/439 (19%)
		NMDAR2_C	850..>925	CDD:463148	1/5 (20%)