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Protein Alignment Ir84a and Grin2a

DIOPT Version :9

Sequence 1:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_036705.3	Gene:	Grin2a / 24409	RGDID:	2737	Length:	1464	Species:	Rattus norvegicus

Alignment Length:	692	Identity:	126/692 - (18%)
Similarity:	228/692 - (32%)	Gaps:	197/692 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 MSANFED--------------LMFYGSPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFI- 132
            :..:|||              ::.|.|...|||:|:.            |...|.......|.:
  Rat   206 LDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSE------------ARSLGLTGYDFFWIVP 258

  Fly   133 -LGSGRESLPVEQLIDQLLS-GYRMGIDADITVALRGPDNASMLF-----------------YDV 178
             |.||...|..::....|:| .|.   |.|.::..|..|...:|.                 ...
  Rat   259 SLVSGNTELIPKEFPSGLISVSYD---DWDYSLEARVRDGLGILTTAASSMLEKFSYIPEAKASC 320

  Fly   179 YRISRQANTPL----------IIEKKGLWTHSGGYQ-----------------KFGNFKNTWVIR 216
            |..:.:..|||          ..:.|.|.....|||                 |.|.::|.
  Rat   321 YGQAEKPETPLHTLHQFMVNVTWDGKDLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENQ---- 381

  Fly   217 RRNFLNVTLIGSTVLTEKPPGFGDMEYLADDKQL-------------QQLDPMQ----------R 258
                   ||.....:..:...|.|.|  .||..|             :.:||:.          |
  Rat   382 -------TLSLRHAVWPRYKSFSDCE--PDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR 437

  Fly   259 KTYQL------------------FQLVERM-----FNLSLAISLTDKWGELLDNGSWSGVMGQVT 300
            |..::                  ..:::::     |...|.:....|.|:.::| .|:|::|:|.
  Rat   438 KFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNN-VWNGMIGEVV 501

  Fly   301 SREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNIFFEPLSNQVW--WCVLAL 363
            .:.|..||..:....:|...|.:|.......|..:......:...:.|.||.|..||  ..|:.|
  Rat   502 YQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLL 566

  Fly   364 VTGSTILLLFH----VRLERMLS----------NMENRFSFVWFTMLETYLQ-QGPANEIFRLFS 413
            :..:..:.:|.    |...|.|:          .:......:|..:....:. |.|...     :
  Rat   567 IVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGT-----T 626

  Fly   414 TRLLISLSCIFSFMLMQFYGAFIVGSLLSE------SARSIVNLQALYDSN--LAIGM------- 463
            :::::|:...|:.:.:..|.|.:...::.|      :..|....|..:|.:  ...|.
  Rat   627 SKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTE 691

  Fly   464 ENISYNFPIFTNTSNQLVRDVYVKKICKSG-EHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLE 527
            .||..|:|....         |:.:..:.| |..::||:.|.    ...|.:..|:       |.
  Rat   692 RNIRNNYPYMHQ---------YMTRFNQRGVEDALVSLKTGK----LDAFIYDAAV-------LN 736

  Fly   528 LQMDEAEFCDLQEVMFNLPYDS---GSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPD 589
            .:....|.|.|..:.....:.:   |..:.|||||:..:..|||.|...|.::..:..|:.....
  Rat   737 YKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGICH 801

  Fly   590 CSLFKTSQAEVDLEHFAPALFALALAMVASALVFLLELFLHW 631
            ....:...:::|:::.|...:.||.||..|.:.|:.|...:|
  Rat   802 NEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYW 843

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.