Protein Alignment Ir84a and glr-3

DIOPT Version :9

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_492017.3
• Gene: glr-3 / 172449
• WormBaseID: WBGene00001614
• Length: 836
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 134/603 - (22%)
• Similarity: 231/603 - (38%)
• Gaps: 158/603 - (26%)

  Fly    94 GSPRTAVLVLNSEHVLVRR----QVF-----GVASEAG------YFNNSLAWFILGSGRESLPVE 143
            |.|.|..:.:::..:|:|.    |::     |.:.::|      :|.|.||
 Worm   290 GVPYTTSIWIDTLRLLIRSMKSIQIWDEPRCGSSWKSGSDIKKRFFENPLA-------------- 340

  Fly   144 QLIDQLLSGYRMGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTHSGGYQKFGN 208
                        ||..|:..|..|               .::|..|.:.::.|     .:|||..
 Worm   341 ------------GISGDLHWAPSG---------------ERSNYTLHVYRRTL-----SFQKFAE 373

  Fly   209 FKNTWVIRRRNFLN------------VTLIGS----TVLTEKP----PGFGDME-YLADDKQLQQ 252
                |..|.|...:            :||.|.    :|..|.|    ...|..| |..|  .|.:
 Worm   374 ----WSSRTRRIASSEAVVIANSSEKLTLEGKHLKISVYLEAPFVMITSNGSYEGYCID--LLHK 432

  Fly   253 LDPMQRKTYQLFQLVERMFNLSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDR 317
            :..:.:.||.:.::.:            :.:|....||.|||::|::...:||.||..:.....|
 Worm   433 IANILKFTYTIQKVRD------------NAYGSKESNGKWSGMVGELQRGDADLAVASLTISYGR 485

  Fly   318 QPYVQYSAVLHTQNIHFLFRHPRRSHIKNI----FFEPLSNQVWWCVLA--LVTGSTILLLFHV- 375
            ...:.::.......|..||:.||   |::.    |.:|||.|||....|  .|....|.::..:
 Worm   486 SEVIDFTVPYMHLGISILFKKPR---IRDSDWFKFMDPLSTQVWIMTFASYFVVSVAIWIIAKIS 547

  Fly   376 ---RLERMLSN-----MENRFSF---VWFTMLETYLQQGPANEIF-RLFSTRLLISLSCIFSFML 428
               :.||...|     ::|:||.   .|||:. :.:|||  :|:. |..|||||..:...|:.:|
 Worm   548 PYEQFERDEDNGQYKPVDNQFSLRNSFWFTVC-SLMQQG--SELCPRAASTRLLTGIWWFFALIL 609

  Fly   429 MQFYGAFIVGSLLS-------ESARSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQLVRDVYV 486
            :..|.|.:...|.:       |:|..:.....:....|..| ..:|     |.|.|.....:...
 Worm   610 ISSYTANLAAVLTTRRMETPIENADDLAAQTKIKYGTLGRG-STMS-----FFNESKIETYERMW 668

  Fly   487 KKICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDE---AEFCDLQEV---MFNL 545
            :.:..|....:.|.::|..|:....:|:          |:|..|.|   ...|:|.::   :...
 Worm   669 QLMSSSPGLFVQSSKEGIARVKSSDYAY----------LMESSMLEYAVERDCELMQIGGLIDQK 723

  Fly   546 PYDSGSVMPKGSPWREHLAHALLHFR-ATGLLQYNDKKWMVRRPDCSLFKTSQAEVDLEHFAPAL 609
            .|..|  :|||||:||.::.|:|..: .|.|.:..:|.|..:...|...|....: |.|......
 Worm   724 GYGIG--LPKGSPYRELISTAILRLQEKTELTELKEKWWKDKSVVCEQPKRKDQD-DGESIGGIF 785

  Fly   610 FALALAMVASALVFLLEL 627
            ..|.:.:|.:|::.:.||
 Worm   786 IILVVGLVLTAVLVIFEL 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020	4/17 (24%)
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	98/414 (24%)
		Lig_chan	355..602	CDD:278489	66/275 (24%)
glr-3	NP_492017.3	PBP1_iGluR_non_NMDA-like	21..385	CDD:380591	26/144 (18%)
		Periplasmic_Binding_Protein_Type_2	401..761	CDD:419667	95/397 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010