Protein Alignment Ir84a and gria3a

DIOPT Version :9

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_005165152.1
• Gene: gria3a / 170452
• ZFINID: ZDB-GENE-020125-5
• Length: 903
• Species: Danio rerio
• Alignment Length: 568
• Identity: 134/568 - (23%)
• Similarity: 231/568 - (40%)
• Gaps: 115/568 - (20%)

  Fly    93 YGSPRT--AVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFILGSGRESLPVEQLIDQLLSGYRM 155
            |.|..|  |:||:......:|||...: |..|...:.||       ..::|..|.|| :....:|
Zfish   298 YTSALTHDAILVIAEAFRYLRRQRVDI-SRRGSAGDCLA-------NPAVPWSQGID-IERALKM 353

  Fly   156 ----GIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTHSGGYQKFGNFKNTWVIR 216
                |:..:|.....|  ..|....|||.:.     |....|.|.|..   ::||     .:::.
Zfish   354 VQVQGMTGNIQFDSFG--RRSNYTVDVYEMK-----PGGARKIGYWNE---FEKF-----VYIVE 403

  Fly   217 RR------NFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPMQRKTYQLFQLVERM----- 270
            ::      :..|.|::.:|:: |.|       |:...:...||:...|.......|...:
Zfish   404 QQVTNESSSVENRTIVVTTIM-EAP-------YVMYKRNYMQLEGNDRYEGYCVDLASEIAKHVG 460

  Fly   271 FNLSLAISLTDKWGEL-LDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHF 334
            ....|:|....|:|.. .:..:|:|::|::....||.||.|:...|.|:..:.:|....:..|..
Zfish   461 IKYKLSIVADGKYGARDPETKTWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISI 525

  Fly   335 LFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLE----RMLSNMENR------- 387
            :.:.|::|..... |.:||:.::|.|::....|.:::|....|..    .:..|.|.:
Zfish   526 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLDDNEETKDPQTPPD 590

  Fly   388 -------FSFVWFTMLETYLQQG----PANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLL 441
                   |:.:||: |..::|||    |     |..|.|::..:...|:.:::..|.|.:...|.
Zfish   591 PPNDFGIFNSLWFS-LGAFMQQGCDISP-----RSLSGRIVGGVWWFFTLIIISSYTANLAAFLT 649

  Fly   442 SESARSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQLVR----DVYVK--KICKSGEHNIM-- 498
            .|  |.:..:::..|  ||...| |:|. .:.:.::.:..|    .||.|  ...||.|.::.
Zfish   650 VE--RMVSPIESAED--LAKQTE-IAYG-TLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFVK 708

  Fly   499 SLQQGAERI--IQGRFAFHTAIDRMYRLLLELQMDE----AEFCDLQEVMFNLPYDS---GSVMP 554
            :...|..|:  .:|:|||          |||..|:|    .:.||..:|..||  ||   |...|
Zfish   709 TTPDGVARVRKSKGKFAF----------LLESTMNEYIEQRKPCDTMKVGGNL--DSKGYGVATP 761

  Fly   555 KGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAEVDL 602
            |||..|..:..|:|.....|:|.....||...:.:|.. |.|.::|.|
Zfish   762 KGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGT-KDSGSKVSL 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020	6/20 (30%)
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	96/406 (24%)
		Lig_chan	355..602	CDD:278489	71/285 (25%)
gria3a	XP_005165152.1	PBP1_iGluR_AMPA_GluR3	28..399	CDD:107382	31/124 (25%)
		ANF_receptor	39..382	CDD:279440	25/94 (27%)
		PBP2_iGluR_AMPA	415..797	CDD:270433	98/413 (24%)
		Lig_chan	547..810	CDD:278489	72/287 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591584
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940