Protein Alignment Ir84a and Grin2d

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 672
• Identity: 129/672 - (19%)
• Similarity: 233/672 - (34%)
• Gaps: 193/672 - (28%)

  Fly   114 VFGVASEAGYFNNSLAWFIL-----GSGRESLPVEQLIDQLL---------------SGYR---- 154
            ||..|.|||.......||::     |.|...:|.|.|   ||               :|:|
Mouse   258 VFRAAEEAGLTGPGYVWFMVGPQLAGGGGSGVPGEPL---LLPGGAPLPAGLFAVRSAGWRDDLA 319

  Fly   155 MGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTHSGG--YQKFGNFKNTWVIRR 217
            ..:.|.:.|..||   |..|..| |....:.......:.:   ||.|.  ::.|.|.  ||..|.
Mouse   320 RRVAAGVAVVARG---AQALLRD-YGFLPELGHDCRAQNR---THRGESLHRYFMNI--TWDNRD 375

  Fly   218 RNF-------------LNVT------LIGS----TVLTEKP--PGFGDMEYLADDKQ-------- 249
            .:|             :::|      ::||    |:..:.|  ..:|......||.|
Mouse   376 YSFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLE 440

  Fly   250 ------LQQLDPMQ--------------RKTYQL----------------------FQLVERM-- 270
                  ::..||:.              .:|:.|                      ..:::|:
Mouse   441 ERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSLVAPRSPPPDAPRPEKRCCKGFCIDILKRLAH 505

  Fly   271 ---FNLSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNI 332
               |:..|.:....|.|:.:| |.|:|::|:|..:.||.|:..:....:|...|.:|.......|
Mouse   506 TIGFSYDLYLVTNGKHGKKID-GVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGI 569

  Fly   333 HFLFRHPRRSHIKNIFF-----------EPLSNQVW--WCVLALVTGSTILLLFH----VRLERM 380
            ..:......:...:.|.           ||.|..||  ..|:.|...:..:.:|.    |...|.
Mouse   570 SVMVARSNGTVSPSAFLAFAWLMPPMSPEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRS 634

  Fly   381 LSNME----NRFSF---VWFTMLETYLQQGPANEIFRLFSTRLLISLSCIFSFMLMQFYGAFIVG 438
            |:..:    :.|:.   :|......:....|. |..|..::::::.:...|:.:.:..|.|.:..
Mouse   635 LATGKRPGGSTFTIGKSIWLLWALVFNNSVPV-ENPRGTTSKIMVLVWAFFAVIFLASYTANLAA 698

  Fly   439 SLLSE---------SARSIVNLQALYDSNLAIGM-------ENISYNFPIFTNTSNQLVRDVYVK 487
            .::.|         |.|.....|..|.. |..|.       :||..|:|   :..:.:||
Mouse   699 FMIQEEYVDTVSGLSDRKFQRPQEQYPP-LKFGTVPNGSTEKNIRSNYP---DMHSYMVR----- 754

  Fly   488 KICKSGEHNIMSLQQGAERIIQGR---FAFHTAIDRMYRLLLELQMDEAEFCDL-----QEVMFN 544
                   :|...:::...::..|:   |.:..|:       |.....:.|.|.|     .:|...
Mouse   755 -------YNQPRVEEALTQLKAGKLDAFIYDAAV-------LNYMARKDEGCKLVTIGSGKVFAT 805

  Fly   545 LPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAEVDLEHFAPAL 609
            ..|  |..:.|||.|:..:..|||.|.....::..::.|:.........:...:::|:::.|...
Mouse   806 TGY--GIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGICHNDKIEVMSSKLDIDNMAGVF 868

  Fly   610 FALALAMVASALVFLLELFLHW 631
            :.|.:||..|.|||..|..::|
Mouse   869 YMLLVAMGLSLLVFAWEHLVYW 890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	19/83 (23%)
		Lig_chan	353..602	CDD:459656	50/285 (18%)
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:471960	38/168 (23%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	76/443 (17%)