Protein Alignment Ir84a and Grik3

DIOPT Version :9

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001074566.1
• Gene: Grik3 / 14807
• MGIID: 95816
• Length: 919
• Species: Mus musculus
• Alignment Length: 669
• Identity: 140/669 - (20%)
• Similarity: 254/669 - (37%)
• Gaps: 129/669 - (19%)

  Fly    14 IILTAFLRVLQIESINTNFLELAAFEDF-LRSEHLSHVLVVRGDDADGDWKIECHQKLLANYRVQ 77
            |..|..|..|.:|....:.:.|..|... :.:.|:|.::        ..|.:|   :|.|..|.:
Mouse   258 IFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIV--------EKWAME---RLQAAPRAE 311

  Fly    78 FYRPEMSANFEDLMFYGSPRTAVLVLNSEHVL----VRRQVFGVAS------EAGYFNNSLAWFI 132
                  |...:.:|.    ..|.|:.::.|::    .|.....|.|      :|..|......||
Mouse   312 ------SGLLDGVMM----TDAALLYDAVHIVSVCYQRAPQMTVNSLQCHRHKAWRFGGRFMNFI 366

  Fly   133 LGSGRESLPVEQLIDQLLSGYRMGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLW 197
            ..:..|.| ..:::....||.|...|.|| ::|:...                     :||.|:|
Mouse   367 KEAQWEGL-TGRIVFNKTSGLRTDFDLDI-ISLKEDG---------------------LEKVGVW 408

  Fly   198 THSGGYQKFGNFKNTWVIRRR------NFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDPM 256
            :.:.|      ...|.|.:.|      :..|.:||.:||| |:|    .:.:...|:.|...|..
Mouse   409 SPADG------LNITEVAKGRGPNVTDSLTNRSLIVTTVL-EEP----FVMFRKSDRTLYGNDRF 462

  Fly   257 QRKTYQLFQLVERMFNLSLAISLTD--KWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQP 319
            :.....|.:.:..:...|..|.|.:  |:|...|.|.|:|::.::...:||.||.|:.....|:.
Mouse   463 EGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREK 527

  Fly   320 YVQYSAVLHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLERM--- 380
            .:.:|....|..:..|:|.|..::.... |..|||..:|..||....|.:.:|....|....
Mouse   528 AIDFSKPFMTLGVSILYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWY 592

  Fly   381 --------LSNMENRFSFV---WFTMLETYLQQGPANEIF-RLFSTRLLISLSCIFSFMLMQFYG 433
                    ...:||.|:.:   ||.| .:.:|||  :|:. :..|||::..:...|:.:::..|.
Mouse   593 DAHPCNPGSEVVENNFTLLNSFWFGM-GSLMQQG--SELMPKALSTRIIGGIWWFFTLIIISSYT 654

  Fly   434 AFIVGSLLSESARSIVNL--QALYDSNLAIGMENISYNFPIFTNTSNQLVRDVYV------KKIC 490
            |.:...|..|...|.::.  .....:.:..|..........|..:.......::.      ..:.
Mouse   655 ANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALV 719

  Fly   491 KSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLLLE---LQMDEAEFCDLQEV---MFNLPYDS 549
            |:.|       :|.:|.:...:|          ||:|   ::......|:|.::   :.:..|..
Mouse   720 KNNE-------EGIQRTLTADYA----------LLMESTTIEYITQRNCNLTQIGGLIDSKGYGI 767

  Fly   550 GSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAE-VDLEHFAPALFALA 613
            |:  |.|||:|:.:..|:|..:....|....:||. |...|...:..:|. :.::........||
Mouse   768 GT--PMGSPYRDKITIAILQLQEEDKLHIMKEKWW-RGSGCPEEENKEASALGIQKIGGIFIVLA 829

  Fly   614 LAMVASALVFLLELFLHWL 632
            ..:|.|.||.:.| |::.|
Mouse   830 AGLVLSVLVAVGE-FIYKL 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020	10/61 (16%)
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	83/392 (21%)
		Lig_chan	355..602	CDD:278489	52/276 (19%)
Grik3	NP_001074566.1	PBP1_iGluR_Kainate_GluR5_7	34..417	CDD:107388	40/208 (19%)
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	85/395 (22%)
		Glutamate binding. /evidence=ECO:0000250	690..692		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846541
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840