Protein Alignment Ir84a and Grik2

DIOPT Version :9

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_011241422.1
• Gene: Grik2 / 14806
• MGIID: 95815
• Length: 943
• Species: Mus musculus
• Alignment Length: 502
• Identity: 106/502 - (21%)
• Similarity: 197/502 - (39%)
• Gaps: 83/502 - (16%)

  Fly   191 IEKKGLWTHSGGYQKFGNFKNTWVIRRRNFLNVTLIGSTVLTEKPPGFGDMEYLADDKQLQQLDP 255
            :||.|.|..|.|.....:.|........:..|.:||.:|:| |:|    .:.:...||.|...|.
Mouse   399 LEKIGTWDPSSGLNMTESQKGKPANITDSLSNRSLIVTTIL-EEP----YVLFKKSDKPLYGNDR 458

  Fly   256 MQRKTYQLFQLVERMFNLSLAISLTD--KWGELLD-NGSWSGVMGQVTSREADFAVCPIRFVLDR 317
            .:.....|.:.:..:...:..|.|.:  |:|...| ||.|:|::.::...:||.||.|:.....|
Mouse   459 FEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVR 523

  Fly   318 QPYVQYSAVLHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVR----- 376
            :..:.:|....|..|..|:|.|..::.... |..|||..:|..:|....|.:.:|....|
Mouse   524 EKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARQSKFS 588

  Fly   377 ------------------LERMLSNME-NRFS-FVW----------------FTMLETY------ 399
                              .:.:.|.|| ..|| :.|                ||:|.::
Mouse   589 WFKYPNCSHYHHSQRCLCTQHLESYMELCLFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGA 653

  Fly   400 -LQQGPANEIF-RLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNL--QALYDSNLA 460
             :|||  :|:. :..|||::..:...|:.:::..|.|.:...|..|...|.::.  .....:.:.
Mouse   654 LMQQG--SELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIE 716

  Fly   461 IGMENISYNFPIFTNTSNQLVRDVYVKKICKSGEHNIMSLQQGAERIIQGRFAFHTAIDRMYRLL 525
            .|..........|..:.......::.....:.....:.|.::|.:|::...:||          |
Mouse   717 YGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAF----------L 771

  Fly   526 LE---LQMDEAEFCDLQEV---MFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWM 584
            :|   ::......|:|.::   :.:..|..|:  |.|||:|:.:..|:|..:..|.|....:||.
Mouse   772 MESTTIEFVTQRNCNLTQIGGLIDSKGYGVGT--PMGSPYRDKITIAILQLQEEGKLHMMKEKWW 834

  Fly   585 VRRPDCSLFKTSQAE-VDLEHFAPALFALALAMVASALVFLLELFLH 630
             |...|...::.:|. :.:::.......||..:|.|..|.:.| ||:
Mouse   835 -RGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGE-FLY 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	86/421 (20%)
		Lig_chan	355..602	CDD:278489	54/304 (18%)
Grik2	XP_011241422.1	PBP1_iGluR_Kainate	37..414	CDD:380605	6/14 (43%)
		Periplasmic_Binding_Protein_Type_2	430..835	CDD:389745	88/424 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846550
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840