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Protein Alignment Ir84a and Gria1

DIOPT Version :9

Sequence 1:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus

Alignment Length:	621	Identity:	137/621 - (22%)
Similarity:	243/621 - (39%)	Gaps:	142/621 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 RVQFYRPEMSANFEDLMFYGSPRT--AVLVLNSEHVLVRRQVFGVA--SEAG--YFNNSLAWFIL 133
            ||.:.||:          |.|..|  .|.|:......:|||...::  ..||  ..|.::.|
Mouse   280 RVDWKRPK----------YTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPW--- 331

  Fly   134 GSGRESLPVEQLIDQLLSGYRM-GIDADITVALRGPDNASMLFYDVYRISRQANTPL-IIEKK-- 194
            |.|   :.:::.:.|:    |. |:..::....:|               |:.|..| :||.|
Mouse   332 GQG---IDIQRALQQV----RFEGLTGNVQFNEKG---------------RRTNYTLHVIEMKHD 374

  Fly   195 -----GLWTHSGGY-------QKFGNFKNTWVIRRRNFLNVTLIGSTVLTEKPPGFGDMEYLADD 247
                 |.|.....:       |..|:  |:.|..|      |.|.:|:| |.|       |:...
Mouse   375 GIRKIGYWNEDDKFVPAATDAQAGGD--NSSVQNR------TYIVTTIL-EDP-------YVMLK 423

  Fly   248 KQLQQLDPMQRKTYQLFQLVERM-----FNLSLAISLTDKWGEL-LDNGSWSGVMGQVTSREADF 306
            |...|.:...|......:|...:     ::..|.|....|:|.. .|..:|:|::|::....||.
Mouse   424 KNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADV 488

  Fly   307 AVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTIL 370
            ||.|:...|.|:..:.:|....:..|..:.:.|::|..... |.:||:.::|.|::....|.:::
Mouse   489 AVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV 553

  Fly   371 LL--------------FHVRLERMLSNMENRFSF---VWFTMLETYLQQG----PANEIFRLFST 414
            |.              |....::..|:..|.|..   :||: |..::|||    |     |..|.
Mouse   554 LFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFS-LGAFMQQGCDISP-----RSLSG 612

  Fly   415 RLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVNLQALYD----SNLAIGMENISYNFPIFTN 475
            |::..:...|:.:::..|.|.:...|..|  |.:..:::..|    :.:|.|..........|..
Mouse   613 RIVGGVWWFFTLIIISSYTANLAAFLTVE--RMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRR 675

  Fly   476 TSNQLVRDVYVKKICKSGEHNIM--SLQQGAERI--IQGRFAFHTAIDRMYRLLLELQMDE---- 532
            :...:...::.  ..||.|.::.  :.::|..|:  .:|::|:          |||..|:|
Mouse   676 SKIAVFEKMWT--YMKSAEPSVFVRTTEEGMIRVRKSKGKYAY----------LLESTMNEYIEQ 728

  Fly   533 AEFCDLQEVMFNLPYDS---GSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDC---- 590
            .:.||..:|..||  ||   |...||||..|..:..|:|.....|:|.....||...:.:|
Mouse   729 RKPCDTMKVGGNL--DSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKD 791

  Fly   591 SLFKTSQAEVDLEHFAPALFALALAMVASALVFLLE 626
            |..|...:.:.|.:.|...:.|...:..:.||.|:|
Mouse   792 SGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIE 827

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.