Protein Alignment Ir84a and grin2ba

DIOPT Version :10

• Sequence 1: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001429729.1
• Gene: grin2ba / 110438919
• ZFINID: ZDB-GENE-090821-2
• Length: 1606
• Species: Danio rerio
• Alignment Length: 741
• Identity: 130/741 - (17%)
• Similarity: 260/741 - (35%)
• Gaps: 193/741 - (26%)

  Fly    25 IESINTNFLELAAFEDF---LRSE--------HLSHVLVVRGDDADGDWKIECHQKLLANYRVQF 78
            |.||.|.:  ...::||   :||.        .|..||::.....|||.||:...|.|.:..:..
Zfish   216 IFSIVTTY--YPGYQDFVTKIRSTIENSFVGWELEEVLLLDMSVDDGDAKIQNLLKKLQSPVILL 278

  Fly    79 YRPEMSANFEDLMFYGSPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFI---LGSGRESL 140
            |..:..||.                          :|.||...|.......|.:   :....:.:
Zfish   279 YSTKEEANI--------------------------IFQVAHSVGLTGYGYTWIVPSLVAGDADHI 317

  Fly   141 PVE---QLIDQLLSGYRMGIDADIT--VAL-----------RGP--------------------D 169
            |.|   .:|......:..|::|.:.  ||:           |||                    :
Zfish   318 PAEFPTGMISVSYDEWDYGLEARVRDGVAVIATATSTMMMDRGPHTLLKSECHGAPDKKSPMTGN 382

  Fly   170 NASMLFY---------------DVYRISRQANTPLIIEKKGLWTHSGGYQKFGNFK---NTW--- 213
            |..:|.|               |.|::..:. ..::::|:..|...|.::. |:..   :.|
Zfish   383 NNEVLRYLMNVTFEGRNLSFSEDGYQMHPKL-VIILLDKERQWDRVGKWEN-GSLSMKYHVWPRF 445

  Fly   214 ------VIRRRNFLNVTLIGST--VLTEKPPGFGDMEYLADD---------KQLQQLDPMQRKTY 261
                  ..|..:.|::..:...  |:.|      |::.|:..         |||:.|:..|....
Zfish   446 ELYSGPEAREDDHLSIVTLEEAPFVIVE------DVDPLSGTCMRNTVPCRKQLKALNQTQDSAV 504

  Fly   262 QL--------FQLVERM-----FNLSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRF 313
            .:        ..:::::     |...|.:....|.|:.: ||:|:|::|:|..:.|..||..:..
Zfish   505 YIKRCCKGFCIDILKKIAKNVKFTYDLYLVTNGKHGKKI-NGTWNGMVGEVVLKNAHMAVGSLTI 568

  Fly   314 VLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNIFFEPLSNQVW---WCVLALVTGSTILLLFH- 374
            ..:|...:.:|.......|..:......:...:.|.||.|..||   :.:|.||:...:.:..:
Zfish   569 NEERSEVIDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWIMMFVMLLLVSAIAVFIFEYF 633

  Fly   375 --VRLERMLSN----------MENRFSFVWFTMLETYLQ-QGPANEIFRLFSTRLLISLSCIFSF 426
              |...|.|::          :......:|..:....:. |.|     |..::::::|:...|:.
Zfish   634 SPVGYNRCLADGREAGGPSFTIGKAIWLLWGLVFNNSVPVQNP-----RGTTSKIMVSVWAFFAV 693

  Fly   427 MLMQFYGAFIVGSLLSESARSIVNLQALYDSNLAIGMENIS-----YNFPIFTNTSNQL-----V 481
            :.:..|.|.:...::.|  ..:..:..|.|..    .:|.:     :.|....|.|.:.     .
Zfish   694 IFLASYTANLAAFMIQE--EYVDQVSGLSDKK----FQNPNDFSPPFRFGTVPNGSTERNIRNNY 752

  Fly   482 RDVYVKKICKSGEHNIMSLQQGAERIIQGR---FAFHTAIDRMYRLLLELQMDEAEFCDLQEVMF 543
            ||:: ..:.|..:.|::   :..|.:..|:   |.:..|:       |.......|.|.|..:..
Zfish   753 RDMH-SYMVKFHQRNVV---EALESLKTGKLDAFIYDAAV-------LNYMAGRDEGCKLVTIGS 806

  Fly   544 NLPYDS---GSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAEVDLEHF 605
            ...:.|   |..:.|.|.|:..:..|:|.....|.::..:..|:.........:...:::|:::.
Zfish   807 GKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHHEKNEVMSSQLDVDNM 871

  Fly   606 APALFALALAMVASALVFLLELFLHW 631
            |...:.|..||..|.:.|:.|...:|
Zfish   872 AGVFYMLGAAMALSLITFIAEHVFYW 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	10/57 (18%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	18/72 (25%)
		Lig_chan	353..602	CDD:459656	45/281 (16%)
grin2ba	NP_001429729.1	None