DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir84a and LOC100334689

DIOPT Version :9

Sequence 1:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	XP_017206939.1	Gene:	LOC100334689 / 100334689	-ID:	-	Length:	991	Species:	Danio rerio

Alignment Length:	730	Identity:	146/730 - (20%)
Similarity:	269/730 - (36%)	Gaps:	165/730 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIKLQVKVISWPLIILTAFLRVLQIESINTNFL--ELAAFEDFLRSEHLSHVLVVRGDDADGDWK 63
            :|:||..:::.....:...:|.|.:::::|..|  |:....:|......||.:..:
Zfish   179 LIRLQELIMAPSRYNIRLKIRQLPMDTVDTRPLLKEMKRSREFRIIFDCSHTMAAQ--------- 234

  Fly    64 IECHQKLLANYRVQFYR------PEMSANFEDLMFYGSPRTAVLVLNSEHVLV---------RRQ 113
             ...|..:.....::|.      ..|:.|.|...|.|...|...:||.::..|         .||
Zfish   235 -ILKQAQMMGMMTEYYHYIFTTLDLMAINLEPYRFCGVNMTGFRILNVDNPQVASIVEKWSLERQ 298

  Fly   114 V---------FGVAS-------------EAGYFN------NSL------AW--------FILGSG 136
            :         .|:.:             ...|.:      |||      .|        ||..|.
Zfish   299 IPPKPDSGLLEGIMTTDAALTYDAVHIVSVSYQHAPQMTVNSLQCHRHKPWRFGGRFMSFIKESH 363

  Fly   137 RESLPVEQLIDQLLSGYRMGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKKGLWTHSG 201
            .:.| ..:|.....:|.|...|.|| |:|:...                     ::|.|.|:.||
Zfish   364 WDGL-TGRLCFNRTTGLRTDFDLDI-VSLKEDG---------------------LQKVGKWSASG 405

  Fly   202 GYQKFGNFKNTWVIRRRNFLNVT-------LIGSTVLTEKPPGFGDMEYL---ADDKQLQQLDPM 256
            |.       |...:.|:|.:|:|       |:.:|:| |:|       |:   ..||.|...|..
Zfish   406 GL-------NITEVPRQNGMNITDSLSNRSLVITTIL-EEP-------YVMLKKSDKALVGNDRF 455

  Fly   257 QRKTYQLFQLVERMFNLSLAISLT--DKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQP 319
            :.....|.:.:..:...|..|.|.  .|:|...|.|.|:|::.::....||.||.|:.....|:.
Zfish   456 EGFCIDLLKELASILGFSYEIHLVPDGKYGFQDDKGQWNGMIRELMEHRADLAVAPLTITFMREK 520

  Fly   320 YVQYSAVLHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLERM--- 380
            .:.:|.......|..|:|.|..::.... |..|::..:|..:|....|.:.:|....|....
Zfish   521 AIDFSKPFLNTGISILYRKPNSTNSGFFSFLNPMTPDIWVYILLAYLGVSCVLFVIARFSPYEWY 585

  Fly   381 --------LSNMENRFSFV---WFTMLETYLQQGPANEIF-RLFSTRLLISLSCIFSFMLMQFYG 433
                    ...:||.|:.:   ||. :.:.:|||  :|:. :..|||::..:...|:.:::..|.
Zfish   586 DAHPCNPGSDVVENNFTLLNSFWFG-VGSLMQQG--SELMPKALSTRIIGGIWWFFTLIIISSYT 647

  Fly   434 AFIVGSLLSESARSIVNL--QALYDSNLAIGMENISYNFPIFTNTSNQLVRDVYVKKICKSGEHN 496
            |.:...|..|...|.|:.  .....:.:..|:.........|..:.......::.....:.....
Zfish   648 ANLAAFLTVERMDSPVDSADDLAKQTKIEYGVVKDGATMSFFKKSRVSTFEKMWAFMSSRQSTSF 712

  Fly   497 IMSLQQGAERIIQGRFAFHTAIDRMYRLLLE---LQMDEAEFCDLQEV---MFNLPYDSGSVMPK 555
            :.|::.|.:|:::..:|          ||:|   ::......|:|.:|   :.:..|..|:  ||
Zfish   713 VKSIEDGIQRVLKSDYA----------LLMESTTIEYVTRRNCNLTQVGGIIDSKGYGIGT--PK 765

  Fly   556 GSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDCSLFKTSQAE---VDLEHFAPALFALALAMV 617
            |||:|:.:..|:|.....|.|....:||.   ...|..:..:.|   :.:::.......||..:|
Zfish   766 GSPYRDKITIAILGILEDGRLHMLKEKWW---SGSSCLEDERYETGPMGIQNLGGIFIVLASGLV 827

  Fly   618 ASALVFLLELFLHWL 632
            .|..|.:.| |::.|
Zfish   828 LSVFVAIGE-FIYKL 841

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020	11/72 (15%)
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	83/396 (21%)
		Lig_chan	355..602	CDD:278489	52/272 (19%)
LOC100334689	XP_017206939.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591545
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840