DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir84a and si:dkey-183j2.10

DIOPT Version :9

Sequence 1:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	XP_001923977.1	Gene:	si:dkey-183j2.10 / 100151589	ZFINID:	ZDB-GENE-130530-729	Length:	465	Species:	Danio rerio

Alignment Length:	415	Identity:	99/415 - (23%)
Similarity:	165/415 - (39%)	Gaps:	100/415 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 LFQLVERM-FNLSLAISLTDKWGELLDNGSWSGVMGQVTSREADFAVCPIRFVLDRQ-------P 319
            |.:|.::: |...:.:.....:|...:||:|:|::|:|...|||.||.|:.....|:       |
Zfish    57 LTELAKKLGFKYKVHLVKDGSYGRQDENGNWNGMIGEVVRGEADLAVAPLTLTAAREKAVGMTKP 121

  Fly   320 YVQYSAVLHTQNIHFLFRHPRRSHIKNI---------FFEPLSNQVWWCVLA--LVTGSTILLLF 373
            |:|       ..|..|.|       |:|         |..|.|.:.|:.:|.  .||...|.::
Zfish   122 YMQ-------TGISILLR-------KDIVSEEAGFFDFLSPFSGETWFGILIAYFVTAVCICIV- 171

  Fly   374 HVRLERMLSNME--------NRFSF---VWFTMLETYLQ-QGPANEIFRLFSTRLLISLSCIFSF 426
                 ..||..|        |.|:.   :|:|.....|| .||..   :..|.|::.....:|:.
Zfish   172 -----GRLSPCEWSQPETEPNHFTLLHSLWYTAGALSLQGAGPHP---KAVSGRVISCTWWLFAV 228

  Fly   427 MLMQFYGAFIVGSLLSESA-------RSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQLVRDV 484
            :|:..|.:.:..:..|:||       ..:.|...:....|| |...:::    |.|::|...|.:
Zfish   229 VLLACYFSSLSSTQGSDSAPLMIKGFEDLANQDVIEYGTLA-GSSTLAF----FKNSNNPSYRRI 288

  Fly   485 YVKKICKSGEHN------IMSLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDEAEFCDL---QE 540
            |        ||.      :.|:.:|.::..:|.:||   |...    :.|.:..|..|:|   .|
Zfish   289 Y--------EHMERRKSFVSSMDEGVQKAKEGNYAF---IGES----VSLDLAVARHCELVRAHE 338

  Fly   541 VMFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRR--PDCSLFKTSQAEVDLE 603
            |:....|  ..|.|.||...::|:.|:|.....|.|.|...||....  ||.:...:.:|
Zfish   339 VIGMRGY--SIVTPLGSAMLKNLSVAILQLSEAGELAYLRTKWWASSCLPDNAKASSLRA----- 396

  Fly   604 HFAPALF-ALALAMVASALVFLLEL 627
            |....:| .||:.:....|:.|.||
Zfish   397 HSMKGIFLVLAIGLGIGVLLSLFEL 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	86/366 (23%)
		Lig_chan	355..602	CDD:278489	63/278 (23%)
si:dkey-183j2.10	XP_001923977.1	PBP2_iGluR_non_NMDA_like	28..381	CDD:270403	88/368 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910