| Sequence 1: | NP_649719.2 | Gene: | MstProx / 40890 | FlyBaseID: | FBgn0015770 | Length: | 965 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_612564.1 | Gene: | TLR4 / 7099 | HGNCID: | 11850 | Length: | 839 | Species: | Homo sapiens |
| Alignment Length: | 1032 | Identity: | 204/1032 - (19%) |
|---|---|---|---|
| Similarity: | 348/1032 - (33%) | Gaps: | 390/1032 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 51 LEVN-WKIPDPNIFIISPISKENRLKLNELIVSDTSYPIRAVDYLRQLGVETVTRFENQINSFKV 114
Fly 115 IERDVHYINGPKSLKIIIQSNLYLNEIIEYINKTTDNVNEIIINAYKTVENQQIALDNLIFNGKS 179
Fly 180 HLRSLTFIGFQIENLSTKPFAQFINLKRMVLTNCTVR---------NLTFLRTLQKSLEHLELDI 235
Fly 236 DNEVDLKYFT----------------------NF---SSLKFMKVRNYIPNKNFTALICTHKNCN 275
Fly 276 FIRGINGLECPK----------------------LCQCL----------YIIDDLELNIDC-SNL 307
Fly 308 GLLQIPPLPIP-------SYGGVKLNFSNNSLSQLPTMTLPGYKLVKRLDVSRNR---------- 355
Fly 356 ----LTNLSINHLPAK------------LDYLDVSFNEIINMGNDVIKYLRTVPIFKQTGNQWTI 404
Fly 405 HCDDKPLLNFFRHLKLIIRMKSAEMKPMFLHSLTELPKGFLKFLGKHFIWLGVRKQEYYLINEEQ 469
Fly 470 LLQSMHRKLNNLNTIMSIYKYMEWLHRKLIFVNREYDLFYIRQMAAPCPHKCECCYSRDSLILKI 534
Fly 535 DCRNKFVYNF-PDIVA--RN------SRLMGKQ-------NMSSPMELHLSKNNISNITIAMLP- 582
Fly 583 ---KELRFLDLRFNNLVTLDDKVLSYLKKNSIKTKLSGNPWNCDCKSRSVLSILRDHEPLEYDVT 644
Fly 645 LKRCNISPTDCPDVCVCCLDNLTWPSFIVDCRGEGLLQMPSLSSRVTYVDLRNNNLTALSQKNRS 709
Fly 710 SIENRSLKLHLLDNPWSCSCNDIEKINFMKSVSSSIVDFTEIKCSNGEKLVSINQHIVCPSDLFY 774
Fly 775 YLALAISLVATIIALNFLIWFRQPVLVWFYEHGVCLSLSAKRELDKDKRFDAFLAFTHKDEA-LL 838
Fly 839 EEFVDRLERGRPRFQLCFYLRDWLAGESI-PDCIGQSIKDSRRIIVLMTENFMNSTWGRLEFRLA 902
Fly 903 -LHATSRDRCKRLIVVLYPNVKNFDSLDSELRTYMAFNTYLE-----RSHPNFWNKL 953 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MstProx | NP_649719.2 | leucine-rich repeat | 325..345 | CDD:275378 | 6/19 (32%) |
| leucine-rich repeat | 346..367 | CDD:275378 | 8/34 (24%) | ||
| leucine-rich repeat | 563..583 | CDD:275378 | 5/23 (22%) | ||
| leucine-rich repeat | 585..610 | CDD:275378 | 6/24 (25%) | ||
| leucine-rich repeat | 611..622 | CDD:275378 | 2/10 (20%) | ||
| TIR | 823..960 | CDD:214587 | 43/139 (31%) | ||
| TLR4 | NP_612564.1 | LRR_RI | 55..>195 | CDD:238064 | 36/186 (19%) |
| LRR 1 | 55..76 | 8/34 (24%) | |||
| leucine-rich repeat | 56..79 | CDD:275378 | 8/56 (14%) | ||
| LRR_8 | 57..114 | CDD:290566 | 12/90 (13%) | ||
| LRR 2 | 79..100 | 3/20 (15%) | |||
| leucine-rich repeat | 80..103 | CDD:275378 | 3/22 (14%) | ||
| LRR_8 | 102..187 | CDD:290566 | 22/97 (23%) | ||
| LRR 3 | 103..124 | 5/25 (20%) | |||
| leucine-rich repeat | 104..127 | CDD:275378 | 6/27 (22%) | ||
| LRR 4 | 127..148 | 4/20 (20%) | |||
| leucine-rich repeat | 128..176 | CDD:275378 | 9/54 (17%) | ||
| leucine-rich repeat | 130..151 | CDD:275380 | 3/20 (15%) | ||
| LRR 5 | 151..172 | 2/20 (10%) | |||
| LRR_RI | 152..456 | CDD:238064 | 72/361 (20%) | ||
| LRR 6 | 176..199 | 8/23 (35%) | |||
| leucine-rich repeat | 177..190 | CDD:275378 | 6/13 (46%) | ||
| leucine-rich repeat | 195..224 | CDD:275380 | 2/28 (7%) | ||
| LRR 7 | 205..225 | 2/19 (11%) | |||
| LRR 8 | 227..247 | 5/22 (23%) | |||
| LRR 9 | 331..351 | 7/22 (32%) | |||
| LRR 10 | 352..373 | 4/20 (20%) | |||
| leucine-rich repeat | 353..374 | CDD:275380 | 4/20 (20%) | ||
| LRR_RI | <372..581 | CDD:238064 | 56/300 (19%) | ||
| LRR 11 | 374..394 | 5/19 (26%) | |||
| LRR_8 | 399..458 | CDD:290566 | 21/102 (21%) | ||
| LRR 12 | 400..422 | 10/33 (30%) | |||
| leucine-rich repeat | 401..423 | CDD:275380 | 10/33 (30%) | ||
| LRR 13 | 423..444 | 7/52 (13%) | |||
| leucine-rich repeat | 424..448 | CDD:275380 | 8/55 (15%) | ||
| LRR_8 | 447..508 | CDD:290566 | 17/106 (16%) | ||
| LRR 14 | 448..456 | 2/7 (29%) | |||
| leucine-rich repeat | 449..472 | CDD:275380 | 4/22 (18%) | ||
| LRR 15 | 472..495 | 9/68 (13%) | |||
| leucine-rich repeat | 473..497 | CDD:275380 | 9/69 (13%) | ||
| LRR 16 | 497..518 | 3/20 (15%) | |||
| leucine-rich repeat | 498..521 | CDD:275380 | 2/22 (9%) | ||
| LRR_8 | 520..581 | CDD:290566 | 15/62 (24%) | ||
| LRR 17 | 521..542 | 6/22 (27%) | |||
| LRR 18 | 545..565 | 5/19 (26%) | |||
| leucine-rich repeat | 546..570 | CDD:275380 | 6/23 (26%) | ||
| LRRCT | 579..625 | CDD:214507 | 16/71 (23%) | ||
| TIR | 674..815 | CDD:214587 | 43/138 (31%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4641 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D147327at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24365 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.920 | |||||