| Sequence 1: | NP_649719.2 | Gene: | MstProx / 40890 | FlyBaseID: | FBgn0015770 | Length: | 965 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003256.1 | Gene: | TLR3 / 7098 | HGNCID: | 11849 | Length: | 904 | Species: | Homo sapiens |
| Alignment Length: | 1085 | Identity: | 239/1085 - (22%) |
|---|---|---|---|
| Similarity: | 379/1085 - (34%) | Gaps: | 358/1085 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 6 TIPDDYCETYCGG------ICNDTVASKTCDREAYDYIATNEYHLIMRDGHLEVNWKIPD---PN 61
Fly 62 IFIISPISKENRLKLNELIVSDTSYPIRAVDYLRQLGVETVTRFENQINS----FKVIER-DVHY 121
Fly 122 INGPKSLKIIIQSNLYLNEIIEYINKT---TDNVNE--IIINAYKTVENQQ-IALDNLIFNGKSH 180
Fly 181 L-RSLTFIGFQIENLSTKPFAQFINLKRMVLTNCTVRNLTFLRTLQKSLEHLELDIDNEVDLKYF 244
Fly 245 TNFSSLKFM-----KVRNYIPNKNFTALICTHKNCNFIRGINGL----------ECPKLCQCLYI 294
Fly 295 IDDLEL-NIDCSNLGLLQIPPLPIPSYGGVKLNFSNNSLSQLPTMTLPGYKL--VKRLDVSRNRL 356
Fly 357 T---NLSINHLPAKLDYLDVSFNEI----------------INMGNDVIKY---LRTVPIFKQTG 399
Fly 400 NQWTIHC--------DDKP-----------------LLNFFRHLKLIIRMKSAEMKPMFLHSLTE 439
Fly 440 LPKGFLKFLGKHFIWLGVRKQEYYLINE--EQLLQSMHRKLNNLNTI-MSIYKYMEWLHRKLIFV 501
Fly 502 NREYDLFYIRQMAAPCPHKCECCYSRDSLILKIDCRNKFVYNFPDIVARNSRLMGKQNMSSPME- 565
Fly 566 ------LHLSKNNISNITIAMLP--KELRFLDLRFNNLVTLDDKVLSYLKKNSIKTKLSGNPWNC 622
Fly 623 DCKSRSVLSILR------DHEPLEYDVTLKRCNISPTDCPDVCVCCLDNL-TWPSFIVDCRGEGL 680
Fly 681 LQMPSLSSRVTYVDLRNNNLTALSQKNRSSIENRSLKLHLLDNPWSCSCNDIE-KINFMKSVSSS 744
Fly 745 IVDFTEIKCSNGEKLVSINQHIVC-----------------------PSDLFYYLALAISLVATI 786
Fly 787 IALNFLIWFRQPVLVWFYEHGVCLSLSAKRELDKD-KRFD--AFLAFTHKDEALLEEFVDRLERG 848
Fly 849 RPRFQLCFYLRDWLAGESIPDCIGQSIKDSRRIIVLMTENFMNSTWGRLEFRLALHATSRDRCKR 913
Fly 914 LIV---VLYPNVKNFDSL---------DSELRTYMAFNTYLERSH 946 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MstProx | NP_649719.2 | leucine-rich repeat | 325..345 | CDD:275378 | 6/19 (32%) |
| leucine-rich repeat | 346..367 | CDD:275378 | 9/23 (39%) | ||
| leucine-rich repeat | 563..583 | CDD:275378 | 11/28 (39%) | ||
| leucine-rich repeat | 585..610 | CDD:275378 | 8/24 (33%) | ||
| leucine-rich repeat | 611..622 | CDD:275378 | 3/10 (30%) | ||
| TIR | 823..960 | CDD:214587 | 33/138 (24%) | ||
| TLR3 | NP_003256.1 | LRRNT | 28..50 | CDD:396168 | 7/34 (21%) |
| leucine-rich repeat | 33..52 | CDD:275380 | 6/31 (19%) | ||
| LRR 1 | 52..73 | 7/42 (17%) | |||
| leucine-rich repeat | 53..76 | CDD:275380 | 8/45 (18%) | ||
| PLN00113 | 72..>542 | CDD:215061 | 133/580 (23%) | ||
| LRR 2 | 76..97 | 4/20 (20%) | |||
| leucine-rich repeat | 77..100 | CDD:275380 | 3/22 (14%) | ||
| LRR 3 | 100..121 | 8/23 (35%) | |||
| leucine-rich repeat | 101..124 | CDD:275380 | 8/25 (32%) | ||
| LRR 4 | 124..145 | 4/20 (20%) | |||
| leucine-rich repeat | 125..148 | CDD:275380 | 3/22 (14%) | ||
| LRR 5 | 148..168 | 8/19 (42%) | |||
| leucine-rich repeat | 149..198 | CDD:275380 | 20/76 (26%) | ||
| LRR 6 | 172..193 | 7/30 (23%) | |||
| LRR 7 | 198..219 | 5/27 (19%) | |||
| leucine-rich repeat | 199..249 | CDD:275380 | 15/68 (22%) | ||
| LRR 8 | 222..244 | 5/29 (17%) | |||
| LRR 9 | 249..270 | 8/38 (21%) | |||
| leucine-rich repeat | 250..275 | CDD:275380 | 10/42 (24%) | ||
| LRR 10 | 275..296 | 7/20 (35%) | |||
| leucine-rich repeat | 276..299 | CDD:275380 | 9/23 (39%) | ||
| LRR 11 | 299..320 | 4/20 (20%) | |||
| leucine-rich repeat | 300..321 | CDD:275380 | 4/20 (20%) | ||
| LRR 12 | 323..344 | 3/20 (15%) | |||
| LRR 13 | 356..377 | 3/20 (15%) | |||
| leucine-rich repeat | 357..380 | CDD:275380 | 2/22 (9%) | ||
| LRR 14 | 380..400 | 4/19 (21%) | |||
| leucine-rich repeat | 381..406 | CDD:275380 | 4/24 (17%) | ||
| LRR 15 | 408..429 | 5/20 (25%) | |||
| leucine-rich repeat | 409..432 | CDD:275380 | 7/22 (32%) | ||
| LRR 16 | 432..454 | 3/21 (14%) | |||
| leucine-rich repeat | 433..457 | CDD:275380 | 5/23 (22%) | ||
| leucine-rich repeat | 458..481 | CDD:275380 | 8/62 (13%) | ||
| LRR 17 | 465..486 | 6/60 (10%) | |||
| leucine-rich repeat | 482..507 | CDD:275380 | 4/24 (17%) | ||
| LRR 18 | 507..528 | 10/20 (50%) | |||
| leucine-rich repeat | 508..531 | CDD:275380 | 10/22 (45%) | ||
| LRR 19 | 531..552 | 9/32 (28%) | |||
| leucine-rich repeat | 532..563 | CDD:275380 | 12/43 (28%) | ||
| LRR_8 | 562..622 | CDD:404697 | 19/78 (24%) | ||
| LRR 20 | 563..584 | 6/20 (30%) | |||
| leucine-rich repeat | 564..585 | CDD:275380 | 6/20 (30%) | ||
| LRR 21 | 587..608 | 6/35 (17%) | |||
| leucine-rich repeat | 588..611 | CDD:275380 | 6/37 (16%) | ||
| LRR 22 | 611..632 | 7/24 (29%) | |||
| leucine-rich repeat | 612..630 | CDD:275380 | 6/21 (29%) | ||
| leucine-rich repeat | 637..659 | CDD:275380 | 6/21 (29%) | ||
| LRRCT | 645..697 | CDD:214507 | 9/65 (14%) | ||
| Tlr3_TMD | 698..730 | CDD:407816 | 10/33 (30%) | ||
| TIR | 755..900 | CDD:214587 | 32/136 (24%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4641 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D147327at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||