| Sequence 1: | NP_649719.2 | Gene: | MstProx / 40890 | FlyBaseID: | FBgn0015770 | Length: | 965 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001305716.1 | Gene: | TLR2 / 7097 | HGNCID: | 11848 | Length: | 784 | Species: | Homo sapiens |
| Alignment Length: | 802 | Identity: | 172/802 - (21%) |
|---|---|---|---|
| Similarity: | 286/802 - (35%) | Gaps: | 238/802 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 328 SNNSLSQLPT-MTLPGYKLVKRLDVSRNRLTNLSINHLP-------------------------- 365
Fly 366 AKLDYLDVSFNEIINMGNDVIKYLRTVPIFKQTGNQW---------------------------T 403
Fly 404 IHCDDKPLLNFFRHLK----------------------LIIRMKS-----------------AEM 429
Fly 430 KPMFLHS--LTELPKGFLKFLGKHFIWLGVRKQEYYLINEEQLLQSMHRKLNNLN---------- 482
Fly 483 TIMSIYKY-------------MEWLHRKLIFVNREYDLFYIRQMAAPCPHKCECCYSRDSLILKI 534
Fly 535 DCRNKFVYNFPDIVARNSRLMGKQNMSSPMELHLSKN-----NISNITIAMLPKELRFLDLRFNN 594
Fly 595 LVTLD--DKVLSYLKKNSIKTKLSGNPWNCDCKSRSVLSILRDHEPLEYDVTLKRCNISPTDCPD 657
Fly 658 VCVCCLDNLTWPSFIVDCRGEGL----LQMP------------------SLSSRVTYVDLRNNNL 700
Fly 701 TALSQKNRSSIENRSLK-LHLLDNPWSCSCNDIEKINFMKSVSSSIVDF-TEIKCSN-----GEK 758
Fly 759 L------VSINQHIVCPSDLFYYLALAISLVATIIALNFLIWFRQPVLVWFYEHGVCLSLSAKRE 817
Fly 818 LDKDKR----FDAFLAFTHKDEALLEE-FVDRLERGRPRFQLCFYLRDWLAGESIPDCIGQSIKD 877
Fly 878 SRRIIVLMTENFMNSTWGRLE-----FRLALHATSRDRCKRLIVVLYP-NVKNFDSLDSELRTYM 936
Fly 937 AFNTYL-----ERSHPNFWNKL 953 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MstProx | NP_649719.2 | leucine-rich repeat | 325..345 | CDD:275378 | 5/17 (29%) |
| leucine-rich repeat | 346..367 | CDD:275378 | 10/46 (22%) | ||
| leucine-rich repeat | 563..583 | CDD:275378 | 5/24 (21%) | ||
| leucine-rich repeat | 585..610 | CDD:275378 | 10/26 (38%) | ||
| leucine-rich repeat | 611..622 | CDD:275378 | 1/10 (10%) | ||
| TIR | 823..960 | CDD:214587 | 43/147 (29%) | ||
| TLR2 | NP_001305716.1 | PLN00113 | <40..>206 | CDD:331614 | 31/169 (18%) |
| leucine-rich repeat | 54..77 | CDD:275380 | 10/22 (45%) | ||
| LRR 1 | 54..77 | 10/22 (45%) | |||
| LRR_8 | 77..135 | CDD:316378 | 9/57 (16%) | ||
| leucine-rich repeat | 78..101 | CDD:275380 | 0/22 (0%) | ||
| LRR 2 | 78..101 | 0/22 (0%) | |||
| leucine-rich repeat | 102..125 | CDD:275380 | 8/22 (36%) | ||
| LRR 3 | 102..125 | 8/22 (36%) | |||
| leucine-rich repeat | 126..150 | CDD:275380 | 2/23 (9%) | ||
| LRR 4 | 126..150 | 2/23 (9%) | |||
| leucine-rich repeat | 151..175 | CDD:275380 | 3/23 (13%) | ||
| LRR 5 | 151..175 | 3/23 (13%) | |||
| LRR 6 | 176..199 | 1/22 (5%) | |||
| leucine-rich repeat | 176..196 | CDD:275380 | 1/19 (5%) | ||
| LRR 7 | 200..223 | 4/22 (18%) | |||
| LRR 8 | 224..250 | 5/25 (20%) | |||
| LRR 9 | 251..278 | 10/33 (30%) | |||
| LRR 10 | 279..308 | 1/28 (4%) | |||
| LRR 11 | 309..337 | 9/38 (24%) | |||
| NEL | <324..>558 | CDD:330839 | 57/270 (21%) | ||
| LRR 12 | 338..361 | 5/30 (17%) | |||
| leucine-rich repeat | 362..388 | CDD:275380 | 5/25 (20%) | ||
| LRR 13 | 362..388 | 5/25 (20%) | |||
| leucine-rich repeat | 389..414 | CDD:275380 | 10/34 (29%) | ||
| LRR 14 | 389..414 | 10/34 (29%) | |||
| leucine-rich repeat | 415..437 | CDD:275380 | 5/24 (21%) | ||
| LRR 15 | 415..437 | 5/24 (21%) | |||
| leucine-rich repeat | 438..478 | CDD:275380 | 11/43 (26%) | ||
| LRR 16 | 438..457 | 6/18 (33%) | |||
| LRR 17 | 458..478 | 5/23 (22%) | |||
| leucine-rich repeat | 479..500 | CDD:275380 | 2/20 (10%) | ||
| LRR 18 | 479..500 | 2/20 (10%) | |||
| leucine-rich repeat | 501..524 | CDD:275380 | 4/24 (17%) | ||
| LRR 19 | 501..524 | 4/24 (17%) | |||
| LRRCT | 533..586 | CDD:214507 | 9/52 (17%) | ||
| TIR | 640..784 | CDD:214587 | 43/143 (30%) | ||
| ATG16L1-binding motif | 761..778 | 5/16 (31%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4641 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D147327at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24365 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.920 | |||||