Protein Alignment MstProx and tlr20f

DIOPT Version :10

• Sequence 1: NP_649719.2
• Gene: MstProx / 40890
• FlyBaseID: FBgn0015770
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: XP_009303059.5
• Gene: tlr20f / 403141
• ZFINID: ZDB-GENE-040220-7
• Length: 956
• Species: Danio rerio
• Alignment Length: 1115
• Identity: 218/1115 - (19%)
• Similarity: 407/1115 - (36%)
• Gaps: 398/1115 - (35%)

  Fly    67 PISKENRLKLNE-----------LIVSDTSY-----PIRAVDYLRQLGVETVTRFENQINSFKV- 114
            |..:::::|..|           ::...|||     |.:.|.|....|..:.:.:..|.|..|.
Zfish     2 PRQEDHKMKNTEELKMGLLFAFFMLFLKTSYVLSWIPGKCVFYSDMEGFTSASTYAGQTNIAKCV 66

  Fly   115 ----IERDV------------------HYINGPKSLKIIIQSNLYLNEIIEYINKT--------- 148
                |:.|:                  |.:..|.|.     |||   ..:||:..|
Zfish    67 SVTDIKEDLRGLPANVLNLYIKMDLHSHGVLSPNSF-----SNL---AXLEYLEITGCFSEIPPK 123

  Fly   149 ----TDNVNEIIINAYKTVENQQIALDNLIFNGKSHLRSLTFIGFQIENLS-TKP--FAQFINLK 206
                ..::..:.|:::.:....::|||      .|||.|||.:.....:|| .:|  |.:...|:
Zfish   124 AFSGLPHLTSLTISSFSSENWCEVALD------FSHLPSLTSLSISYYSLSLLEPNVFEKIPQLQ 182

  Fly   207 RMVLTNCTVRN-------LTFLRTLQK------SLEHLE---------LDIDNEVDLKYFTNFSS 249
            .:.|.:..::|       ||.::.|::      :|.||:         .||..|.:::|    :.
Zfish   183 NLYLIDVRLKNMSEILCRLTNIKKLKQFNLFDDALTHLQKPNCSVFNISDISTEFNIEY----AD 243

  Fly   250 LKFMKVRNYIPN---------KNFTALICTH--KNCNFIRGINGLECPKLCQCLYIIDDLELNID 303
            |       |:.|         |.|..|.|.:  .|.:|:|.::.:...|:......:|.|.:|..
Zfish   244 L-------YLNNVEHVDEGALKVFGKLFCINFGSNTDFLRYLSLIGVHKISSLYVDVDVLNVNDL 301

  Fly   304 CSNLGLLQIPPLPIPSYGGVKLNFSNNSLSQLPTMTLPGYKLVKRLDVSRNRLTNLSIN-HLPAK 367
            |:...|..|.        .:..::...:|.|..|....|.:.:|          |:.:| |..|.
Zfish   302 CTAAKLYSIE--------SIFADYKTINLPQTQTNISEGCRKIK----------NIVLNKHFNAN 348

  Fly   368 LDYLDVSFNEIINMGNDVIKYLRTVPIFKQ--TGNQWTIHCDDKPLLNFFRHLKLIIRMKSAEMK 430
            :  |||  |.::.:.::    |.::.||..  ..:.:...|..||
Zfish   349 I--LDV--NSVVQLFSN----LTSIKIFLHMFRSDDFQSLCASKP-------------------- 385

  Fly   431 PMFLHSLTELPKGFLKFLGKHFIWLGVRKQEYYLINEEQLLQSMHRKLNNLNTIMSIYKYMEWLH 495
                |::.::                                          ::||:..|::::
Zfish   386 ----HAVKQI------------------------------------------SVMSLGPYIDFI- 403

  Fly   496 RKLIFVNREYDLFYIRQMAAPCPHKCECCYSRDSLILKIDCRNKFVYNFPDIVARNSRLMGKQNM 560
                 |:.::..|                   .:||: ::..|..:||..|..     .:|...:
Zfish   404 -----VSFQFTCF-------------------TNLII-LELFNNQIYNIEDFA-----FVGLNKL 438

  Fly   561 SSPMELHLSKNNISNI---TIAMLPKELRFLDLRFNNLVTLDDKVLSYLKK-------------- 608
            .   ||:||.|.:|.|   |.:.| .||..|||:.|:::.::.|...:...
Zfish   439 E---ELYLSGNKLSYIHQHTFSGL-HELMVLDLQGNHIIYIEPKSFGHFMNITTLLLGDLNFSPD 499

  Fly   609 -NSIKTKLS----GNPWNCDCKSRSVLSILRD-HEPLEYDVTLKR-CNISPT-------DCPDVC 659
             :.||..||    |.|  |:..:..:.|.||. |..:..:.||.. .|:..|       ||.::.
Zfish   500 MSLIKVNLSDIFYGIP--CNLSNLFLSSGLRPMHLVMGSNTTLNNGLNLRITGQYVIVEDCNNLL 562

  Fly   660 VCCLDNLTWPSFIVDCRGEGL-LQMPSLSS--------------------------RVTYVDLRN 697
            :..:.:|...:..|.|..|.: ..:||:.|                          ::..:|.:|
Zfish   563 LTSVVSLQINAAYVSCENEFIGKYVPSVVSLEFHSKFSDNIGDLAVINQLVHLKTLKLEDIDFKN 627

  Fly   698 --------NNLTALS----------------QKNRSSIENRSLKL--------------HLLDNP 724
                    :|||.|.                .|:.:::  |.|.|              ||.|..
Zfish   628 QPNLAIMFHNLTKLQTLILANCRIFFLDGSLTKDLTAL--RKLILIPTNTVNILQTFVEHLTDLE 690

  Fly   725 W--------SCSCNDIEKINFMK---SVSSSIVDFT--EIKCSNGEKLVSIN------QHIVCPS 770
            :        .|||:|...::::|   .|..|:.:.|  :::|....::..:|      ::.....
Zfish   691 YVYFEGLGLYCSCDDAWLVSWVKDNRKVEVSMFNPTMQDLQCLIENEVDQLNFVSFVKENCSFDI 755

  Fly   771 DLFYYLALAISL---VATIIALNFLIWFRQPVL----VWFYEHGVCLSLSAKRELDKDKRFDAFL 828
            :..::.:.|:.|   :..::...|:..:.:|..    .||.|   .|.:..|::.    |:|.|:
Zfish   756 EFVFFASTAVFLCIFIVVVLMYKFVGQYFKPFFHIASGWFRE---VLRMKKKQQY----RYDVFV 813

  Fly   829 AFTHKDEA-LLEEFVDRLE-RGRPRFQLCFYLRDWLAGESIPDCIGQSIKDSRRIIVLMTENFMN 891
            :::.|||. ::||.:..|| ||.|..::|.:.||:..|..|.:.|..||..|||.:.|:::|::.
Zfish   814 SYSSKDEHWVMEELLPNLEQRGPPFLRICLHSRDFQLGHDIVENITDSIYASRRTLCLVSQNYLG 878

  Fly   892 STWGRLEFRLALHATSRDRCKRLIVVLYPNVKNFDSLDSEL-------------RTYMAFNTYLE 943
            |.|..||.:||.:....:....||:|.      .:::.|.|             |||:.:....|
Zfish   879 SNWCSLEMQLATYRLQVEHRDILILVF------LETIPSRLLSSHHRLARLVKTRTYLDWPHDPE 937

  Fly   944 RSHPNFWNKL 953
            | |..||::|
Zfish   938 R-HEAFWHRL 946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MstProx	NP_649719.2	PRK15370	<315..>398	CDD:185268	16/85 (19%)
		leucine-rich repeat	325..345	CDD:275378	4/19 (21%)
		leucine-rich repeat	346..367	CDD:275378	4/21 (19%)
		TIR	823..960	CDD:214587	46/146 (32%)
tlr20f	XP_009303059.5	None