Protein Alignment MstProx and tlr4ba

DIOPT Version :10

• Sequence 1: NP_649719.2
• Gene: MstProx / 40890
• FlyBaseID: FBgn0015770
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: XP_009305503.2
• Gene: tlr4ba / 403131
• ZFINID: ZDB-GENE-040219-8
• Length: 824
• Species: Danio rerio
• Alignment Length: 927
• Identity: 202/927 - (21%)
• Similarity: 360/927 - (38%)
• Gaps: 278/927 - (29%)

  Fly   174 IFNGKSHLRSLTFIGFQI--ENLSTKP-------------FAQFINLKRMVLTNCTVRNLTFLRT 223
            |.||:...|.:..:.:..  .|||:.|             |..|:.||:.:..     .|:|||.
Zfish    20 IANGEPCTRIIENLHYSCMGRNLSSIPSSIPSSVQTLDFSFNFFLQLKKTIFP-----VLSFLRV 79

  Fly   224 LQKSLEHLELDIDNEVDLKYFTNFSSLKFMKVRNYIPNKNFTALICTHKNCNFIRGINGLECPKL 288
            |..|..|:. .|:|:.            |..|      ||.|.|..|.....:.       .|..
Zfish    80 LDLSRCHIR-QIENDA------------FYNV------KNLTTLFLTGNPIIYF-------APGC 118

  Fly   289 CQCLY------IID----DLELNIDCSNLGLLQIPPLPIPSYGGVKLNFSNNSLSQLPTMTLP-- 341
            ...||      ::|    .|:|||  :||..||            :||...|   .:.:||||
Zfish   119 LNTLYNLQRLVLVDIGLESLQLNI--NNLTKLQ------------ELNVGTN---YIQSMTLPPF 166

  Fly   342 --GYKLVKRLDVSRNRLTNLSINHLPAKLDYLDVSFNEIINMGNDVIKYLRTVPIFKQTGNQWTI 404
              .:|....||:..|.::.:..:|                           || :.::.|...|:
Zfish   167 MTTFKDFSLLDLHANNISIIRTDH---------------------------TV-VLREIGRNMTL 203

  Fly   405 HCDDKPLLN---------FFRHLKL---IIRMKSAEMKPMFLHSLTELPKGFLKFL---GKHFI- 453
            .....|||:         :.|.|.:   .:...:.:.....||.|......|.|:.   |.||:
Zfish   204 ILTWNPLLHIEPGAFKDVYLRQLDIRSAFVSFSAQKAALKALHGLNVKRLIFGKYREDNGFHFVD 268

  Fly   454 --------WLGVRKQEYYLINEEQLLQSMHRKLNNLNTIM----SIYKYMEWLH----RKLIFVN 502
                    ....::..||::...:...::.|.:.|...|.    :|:| ||.:|    ::|..:|
Zfish   269 NDVLDGLCCFNFQEVSYYVLESAKTTIAIFRCMINATRITVKGGNIFK-METVHFHKTKELYLIN 332

  Fly   503 REYDLFYIRQMAAPCPH-----KCECCYSRDSLI-------------------LKI-DCRNKFVY 542
            ........:|::    |     |.|..::.:.:.                   ||| .|.:..:.
Zfish   333 NGLGTLPTKQLS----HLHTLEKLEITHNSEPIFAEPFTDLPKLQYVDLSDNQLKIKHCCSTLLS 393

  Fly   543 NFPDI----VARNSRLM----GKQNMSSPMELHLSKNNISNI---TIAMLPKELRFLDLRFNNLV 596
            ..|.|    ::.||.:.    |.:.:.|...|..|...:..|   ::....|.||:||:.::: |
Zfish   394 GTPQINYLNLSLNSEISVDVGGFEGLDSLEILDFSYTRVVRIGYLSVLSNLKNLRYLDVSYSS-V 457

  Fly   597 TLDDKVLSYLKKNSIKT-KLSGNPWNCDCKSRSVLSILRDHEPLEYDVTLKRCNISPTDCPDVCV 660
            |..: :..:|..:|:.. |::||.:..:. ::.|.:                 |::..:..|:..
Zfish   458 TFSN-IFCFLGLSSLNVLKMAGNNFQGNV-AKYVFN-----------------NLTLLEHLDMSF 503

  Fly   661 CCLDNLTWPSF-------IVDCRGEGLLQMPSLS----SRVTYVDLRNNNLTALSQKNRSSIENR 714
            |.|..|...||       .::.:|..|:::..|:    .::|...:..|::||:.   ...::|.
Zfish   504 CHLVELHTSSFKYLQRLRHLNVKGNYLIKIDFLTHPNLKQLTSFYVEKNSITAIP---LHVLQNL 565

  Fly   715 SLKLHLLD---NPWSCSCNDIEKINFM------------------KSVSSS----IVDFTEIKCS 754
            .:.|...|   ||..|||:   :.:||                  |::|.:    :.||....|.
Zfish   566 PMNLSEFDLSFNPIDCSCS---QTDFMLWIINNQRVLKQPENILCKTISPNSDFRVTDFDIDHCV 627

  Fly   755 NGEKLVSINQHIVCPSDLFYYLALAISLVATIIALNFLIWFRQPVLVWFYEHGVCLSLSAKRELD 819
            ..:||:               :.|.:..|..|:.|:.|::..|..|.:|:     :.|...|...
Zfish   628 YKKKLI---------------IVLPVFCVVFIVVLSILVYRFQFYLRYFW-----ILLRGYRSPG 672

  Fly   820 KDK-RFDAFLAFTHKDEA-LLEEFVDRLERGRPRFQLCFYLRDWLAGESI-PDCIGQSIKDSRRI 881
            :.: .:|||:.|:..||| ::.|.::.||.|.|..|||.::||:.||:|| .:.|.:.|..||:|
Zfish   673 QQECSYDAFVIFSSYDEAWVMNELMENLENGVPPIQLCLHMRDFQAGKSIASNIIDEGIMGSRKI 737

  Fly   882 IVLMTENFMNSTWGRLEFRLALHATSRDRCKRLIVVLYPNV-----KNFDSLDSELRTYMAFNTY 941
            ||:::::|::|:|.|.||.||......:|...:|:::..:|     |....|...|:.    |||
Zfish   738 IVVVSQHFIDSSWCRFEFELAQSRFLMERNANIIIIILEDVAERKTKKVIGLHKHLKK----NTY 798

  Fly   942 LE-----RSHPNFWNKL 953
            |:     .|:..||.:|
Zfish   799 LKWSRDPLSNMRFWIRL 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MstProx	NP_649719.2	PRK15370	<315..>398	CDD:185268	14/86 (16%)
		leucine-rich repeat	325..345	CDD:275378	7/23 (30%)
		leucine-rich repeat	346..367	CDD:275378	4/20 (20%)
		TIR	823..960	CDD:214587	50/143 (35%)
tlr4ba	XP_009305503.2	None