Protein Alignment MstProx and Toll-9

DIOPT Version :10

• Sequence 1: NP_649719.2
• Gene: MstProx / 40890
• FlyBaseID: FBgn0015770
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: NP_649214.1
• Gene: Toll-9 / 40245
• FlyBaseID: FBgn0036978
• Length: 900
• Species: Drosophila melanogaster
• Alignment Length: 913
• Identity: 178/913 - (19%)
• Similarity: 334/913 - (36%)
• Gaps: 260/913 - (28%)

  Fly   154 EIIINAYKTVENQQIALDNLIFNGKSHLRSLTFIGFQIENL--STKPFAQFINLKRMVLTNCTVR 216
            |:...|:.|:   ..|....:::.:..|:.|:..|.....|  ..:.||:|:|..|:..:|....
  Fly   133 EVFSAAFNTL---TAAPFRTLYSMRESLKLLSLRGNNFAELIPDAEDFARFVNESRLEASNSVPH 194

  Fly   217 NLTFLRTLQKSLEHLELDI-DNEVDLKYFTNFSSLKFMKVRNYIPNKNFTALICTHKN-CNFIRG 279
            :...|      |.|...|: |.|..| ||.|              |.|....|.|.:| .|||:
  Fly   195 HCELL------LLHNTTDLYDRECYL-YFNN--------------NTNMGQSITTGRNYTNFIK- 237

  Fly   280 INGLECPKLCQCLYIIDDL--ELNIDCSNLGLLQIPPLPIPSYGGVKLNFSNNSLSQLPTMTLPG 342
                          ::.|.  :......::.....|.:|    ..|:|:.||.|:..
  Fly   238 --------------VLKDRFDQHGSSSQSIAWATFPKMP----RLVELDISNCSIEY-------- 276

  Fly   343 YKLVKRLDVSRNRLTNLSINHLPAKLDYLDVSFNEIINMGNDVIKYLRTVPIFKQTGNQWTIHCD 407
                    ||:....|:|      .|..|.:|.|:|:.:.:|...|::.|...
  Fly   277 --------VSKEAFRNVS------NLRRLFMSDNKIMTISHDTFYYVQGVQYL------------ 315

  Fly   408 DKPLLNFFRHLKLIIRMKSAEMKPMFLHSLTELPKGFLKFLGKHFIWLGVRKQEYYLINEEQLLQ 472
            |....||..: ...:::.:.||....::.| ::.:...|:| ...|:|.:
  Fly   316 DLSFTNFLTY-SYQLQLPTLEMALSLIYGL-KIQQNVFKYL-PELIYLDL--------------- 362

  Fly   473 SMHRKLNNLNTIMSIYKYMEWLHRKLIFVNREYDLFYIRQMAAPCPHKCECCYSRDSLILKIDCR 537
             .|.|:...:.:...:     |..||.|::                    .||:...::.....:
  Fly   363 -SHSKMTRNSAVAFAH-----LGDKLKFLS--------------------LCYTAIPMVSSTIFK 401

  Fly   538 N------------------------------KFVY----NFPDI----VARNSRLMGK------- 557
            |                              |::|    |..|:    ..:|.:::|.
  Fly   402 NTVLEGLDLSGNPYLSYNIIDDAFDGIANTLKYLYFERSNIKDLEWSKSLKNLQVLGLAGNNINA 466

  Fly   558 ------QNMSSPMELHLSKNNISNITIAMLPKE--LRFLDLRFNNLVTLDDKV------LSYLKK 608
                  |::.|...|.||.|::.|...:.....  ||.|:||.|.:..|.:::      |.||
  Fly   467 LTPAMFQSLESLEILDLSSNHVGNWYRSAFHNNSALRVLNLRSNTINMLSNEMLKDFERLDYL-- 529

  Fly   609 NSIKTKLSGNPWNCDCKSRSVLSILRDHEPLEYDVTLKRCNISPTDCPDVCVCCLDNLTWPSFIV 673
                 .|..|.:.|||..|:|:.:...:.. :.|.:.:..|.|.....:..:...::|     |:
  Fly   530 -----SLGDNDFICDCHLRAVVEVAAANNK-DADCSYRLLNYSQNAVGEEVISLAESL-----II 583

  Fly   674 DCRGEGLLQMPSLSSRVTYVDLRNNNLTALSQKNRSSIENRSLKLHLLDNPW---SCSC------ 729
            |.:   |.|     ||  |:.....:.:.:.:.||:   |..:||......:   .||.
  Fly   584 DRK---LWQ-----SR--YIPWLQRSYSNIREFNRA---NHIIKLRFSSEDYMVAKCSAAQPYHL 635

  Fly   730 NDIEKINFMKSVSSSIVDF--TEIKCSNGE---KLVSINQHIVCPSDLFYYL--------ALAIS 781
            .|::....:|   ..::|:  ::..|.|..   ::..:|..|...|||...|        |:..|
  Fly   636 GDLDGDLTLK---FQLLDYEASQYYCFNNTDQLQVDELNCQIRSMSDLAEELHHVTNTVIAVMGS 697

  Fly   782 LVATIIALNFLIWFRQPVLVWFY---EHGVCLSLSAKRELDK----DKR-----FDAFLAFTHKD 834
            ||...| |.|:|:.::..:.::|   :....||.::|..::|    .:|     :|.|:::...|
  Fly   698 LVGACI-LGFIIYLKRWHIHYYYSSLKSAALLSSASKESVNKFTNISQRDPSAVYDIFISYCQND 761

  Fly   835 EA-LLEEFVDRLERGRPRFQLCFYLRDWLAGESIPDCIGQSIKDSRRIIVLMTENFMNSTWGRLE 898
            .. :|.|.:..:|. .....:|.:.||:..|.:|.|.|...:..|..::::::..|:.|.|.:.|
  Fly   762 RTWVLNELLPNVEE-TGDVSICLHERDFQIGVTILDNIISCMDRSYSLMLIISSKFLLSHWCQFE 825

  Fly   899 FRLALHATSRDRCKRLIVVLYPNV------KNFDSLDSELRTYMAFNTYLERSHPNFWNKLIYSM 957
            ..||.|.......:.||:|...::      |....| .:::||:.:.|..| ....||.:|..|:
  Fly   826 MYLAQHRIFEVSKEHLILVFLEDIPRRKRPKTLQYL-MDVKTYIKWPTAKE-DRKLFWKRLKRSL 888

  Fly   958 PLL 960
            .::
  Fly   889 EVI 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MstProx	NP_649719.2	PRK15370	<315..>398	CDD:185268	18/82 (22%)
		leucine-rich repeat	325..345	CDD:275378	4/19 (21%)
		leucine-rich repeat	346..367	CDD:275378	4/20 (20%)
		TIR	823..960	CDD:214587	35/148 (24%)
Toll-9	NP_649214.1	LRR	198..537	CDD:443914	82/463 (18%)
		leucine-rich repeat	264..287	CDD:275380	9/44 (20%)
		leucine-rich repeat	288..311	CDD:275380	7/22 (32%)
		leucine-rich repeat	312..356	CDD:275380	9/58 (16%)
		leucine-rich repeat	357..381	CDD:275380	5/44 (11%)
		leucine-rich repeat	382..397	CDD:275380	4/34 (12%)
		leucine-rich repeat	405..430	CDD:275380	0/24 (0%)
		leucine-rich repeat	432..453	CDD:275380	4/20 (20%)
		leucine-rich repeat	454..477	CDD:275380	2/22 (9%)
		leucine-rich repeat	478..501	CDD:275380	5/22 (23%)
		leucine-rich repeat	502..525	CDD:275380	7/22 (32%)
		TIR	751..891	CDD:214587	34/142 (24%)