DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment MstProx and rdo

DIOPT Version :9

Sequence 1:NP_649719.2 Gene:MstProx / 40890 FlyBaseID:FBgn0015770 Length:965 Species:Drosophila melanogaster
Sequence 2:NP_001286024.1 Gene:rdo / 35077 FlyBaseID:FBgn0243486 Length:757 Species:Drosophila melanogaster


Alignment Length:539 Identity:109/539 - (20%)
Similarity:197/539 - (36%) Gaps:179/539 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   284 ECPKLCQCLYIIDDL-------------------ELNIDCSNL-------------GLLQIPPLP 316
            :||..|||  .:|||                   ||::|...:             .|.|...|.
  Fly    23 KCPTECQC--SMDDLDRYQAICTKGGLNSLLSPNELDVDVKVIIIRGPRNSITIGPALRQFMKLE 85

  Fly   317 IPSYGGVKLNFSNNSLSQLPTMTLPGYKLVKRLDVSRNRLTNLSINHLPAK--LDYLDVSFNEII 379
            |       |..::::|..:...:..|.|.::.||:|:|.:||::.|:...:  |..||:|.|:::
  Fly    86 I-------LRITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENNFRGQDNLLELDLSKNKVL 143

  Fly   380 NMGNDVIKYLRTVPIFKQTGNQWTIHCDDKPLLNFFRHLKLIIRMKSAEMKPMFLHSLTELPKGF 444
            .|.:..                             ||||..:.|:..|:      :|:.||.   
  Fly   144 RMASST-----------------------------FRHLTDLRRLNLAD------NSIVELV--- 170

  Fly   445 LKFLGKHFIWLGVRKQEYYLINEEQLLQSMHRKLNNLNTIMSIYKYMEWLHRKLIFVNREYDLFY 509
                          ::.:::::..:.|......|.:|                      :.|:| 
  Fly   171 --------------QRNFFMLSRLKYLDLSGNPLQDL----------------------QPDVF- 198

  Fly   510 IRQMAAPCPHKCECC---------YSRDSLILKIDC-RNKFVY----NFPDIVARNSRLMGKQNM 560
             |.:......||..|         |:...|:.::|. ||:|.:    .|.|:......|:....:
  Fly   199 -RDVPELKVLKCRNCQLKKINPQMYNLLPLLSELDLGRNEFKFLDKDEFRDVKRLTKVLLDGNQL 262

  Fly   561 S------SPMELHLSKNNISNITIAMLPKE-------LRFLDLRFNNLVTLDDKVLSYLKKNSIK 612
            |      ..|:..|:..::|...:|.:|.:       |.||||.:|.||.|:.:.:..| .|.:.
  Fly   263 SVVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQLTNLTFLDLSYNKLVRLEPQSIRSL-SNLLT 326

  Fly   613 TKLSGNPWNCDCKSRSVLSILRD----HEPLEYDVTLKRCNISPTDCPDVC-VCCLDNLTWPSFI 672
            ..:|||          ||..||:    .|||.|...|....:.....|.:. :...|..|.|..:
  Fly   327 LNISGN----------VLMDLREMRETFEPLIYYFFLTCSKLFFQLIPQLTHLAIADMGTMPVGL 381

  Fly   673 ---------VDCRGEGL----LQMPSLSSRVTYVDLRNNNLTALSQKNRSSIEN-RSLKLHLLDN 723
                     ::..|..|    |::......:.::||..|.|..:|:.....|:. |:::|.  :|
  Fly   382 LHPFKQLRYLNISGNSLNNTALEVIDPCRELEFLDLSRNQLHGISEDTVLRIQGIRNVRLD--NN 444

  Fly   724 PWSC-SCNDIEKINFMKSV 741
            |..| .|:..:.||.::.:
  Fly   445 PLICDECHMGKLINVVRQL 463

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MstProxNP_649719.2 leucine-rich repeat 325..345 CDD:275378 3/19 (16%)
leucine-rich repeat 346..367 CDD:275378 7/20 (35%)
leucine-rich repeat 563..583 CDD:275378 4/19 (21%)
leucine-rich repeat 585..610 CDD:275378 10/24 (42%)
leucine-rich repeat 611..622 CDD:275378 3/10 (30%)
TIR 823..960 CDD:214587
rdoNP_001286024.1 leucine-rich repeat 84..107 CDD:275380 5/29 (17%)
leucine-rich repeat 108..131 CDD:275380 7/22 (32%)
LRR_8 131..190 CDD:290566 16/110 (15%)
leucine-rich repeat 132..155 CDD:275380 10/51 (20%)
LRR_RI 151..422 CDD:238064 65/328 (20%)
leucine-rich repeat 156..179 CDD:275380 5/45 (11%)
LRR_8 178..262 CDD:290566 18/107 (17%)
leucine-rich repeat 180..203 CDD:275380 6/46 (13%)
leucine-rich repeat 204..251 CDD:275380 11/46 (24%)
leucine-rich repeat 252..275 CDD:275380 3/22 (14%)
LRR_8 274..334 CDD:290566 18/70 (26%)
leucine-rich repeat 276..299 CDD:275380 4/22 (18%)
LRR_4 298..342 CDD:289563 18/54 (33%)
leucine-rich repeat 300..323 CDD:275380 10/23 (43%)
leucine-rich repeat 388..411 CDD:275380 3/22 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4641
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.