Protein Alignment MstProx and Tehao

DIOPT Version :9

• Sequence 1: NP_649719.2
• Gene: MstProx / 40890
• FlyBaseID: FBgn0015770
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: NP_001285901.1
• Gene: Tehao / 34761
• FlyBaseID: FBgn0026760
• Length: 795
• Species: Drosophila melanogaster
• Alignment Length: 1025
• Identity: 237/1025 - (23%)
• Similarity: 390/1025 - (38%)
• Gaps: 355/1025 - (34%)

  Fly    14 TYCGGI---CNDTVASKTCDRE--AYDYIATNEYHLIMRDGH------------LEVNWKIPDPN 61
            |:|.|:   |       ||..|  ...:...:||.:::....            .|:.| :|..|
  Fly    29 TFCLGLSPQC-------TCAAEGNVVRFHCPDEYAMLLEVSEPGASLYMSYYASTELQW-LPRFN 85

  Fly    62 IFIISPISKENRLKLNELIVSDTSYPIRAVDYLRQLGVETVTRFENQINSFK-VIERDV------ 119
            |..:..|..:..:...|..:|         |.|:.|||:||.....:..:.: |:.|||
  Fly    86 ISSLVKIEFDAYIFWPEKFLS---------DLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNG 141

  Fly   120 -------------HY--INGPKSLKIIIQSNLYLNEIIEYINKTTDNVNEIIINAYKTVENQQIA 169
                         |:  :.|.|..|       :.:.:.|        :.|.|.:.:.|:.:..::
  Fly   142 YMETSQPENITTWHFGSVPGLKKFK-------FFSHVPE--------LQESIFHGFDTLRDLHLS 191

  Fly   170 LD------NLIFNGKSHLRSLTFIGFQIENLSTKPFAQFINLKRMVLTNCTVRNLTFLRTLQKSL 228
            ::      |::......|::||     ||:.....|.           |..:|.|..||.|..:|
  Fly   192 VNVTTLPGNMLSTVNGTLKTLT-----IESPGIVSFG-----------NPLLRELQQLRNLSLAL 240

  Fly   229 EHLELDIDNEVDLKYFTNFSSLKFMKVRNYIPNKNFTALICTHKNCNFIRGINGLECPKLCQCLY 293
            .|...:.|.::...:|.:.::|:.:::          |...:..|.:..:|.|.|:..|:..
  Fly   241 IHPFHERDKQLQPHFFGSMTNLEEVRL----------ASATSSVNRSMFKGTNKLQLIKMNG--- 292

  Fly   294 IIDDL-----ELNIDCSNLGLLQIPPLPIPSYGGVKLNFSNNSLSQLPTMTLPGYKLVKRLDVSR 353
             .|||     |:.:|..||..|.:               |.|::..|......|...:..||:|:
  Fly   293 -NDDLMELPGEIFLDQVNLKTLDL---------------SCNAIVTLHEDVFKGLGNLTLLDLSK 341

  Fly   354 NRLTNLSINHLPAKLDYLDVSFNEIINMGNDVIKYLRTVPIFKQTGNQWTIHCDDKPL--LNFFR 416
            |||||||..                               ||             .||  ||..|
  Fly   342 NRLTNLSST-------------------------------IF-------------APLTSLNVLR 362

  Fly   417 HLKLIIRMKSAEMKPMFLHSLTEL-PKGFLKFLGKHFIWLGVRKQEY---YLINEEQLLQSMHRK 477
            ..|               :|||.: |..|...:..::|.: |..|.|   .|:|.|.::.:
  Fly   363 LNK---------------NSLTAMSPSVFQDVVSLNYIEM-VNTQFYGATLLMNYEAVVCT---- 407

  Fly   478 LNNLNTIMSIYKYMEWLHRKLIFVNREYDLFYIRQMAAPCPHKCECCYSRDSLILKIDCRNKFVY 542
                |.....||..||                      .|..:|.|...|....|.:|||...:.
  Fly   408 ----NDEACQYKSAEW----------------------QCDPRCICWVQRSVGSLIVDCRGTSLE 446

  Fly   543 NFPDI-----------VARN--------SRLMGKQNMSSPMELHLSKNNISNITIA-MLPKELRF 587
            ..||:           |..|        |...|..|:|.   |.||.||::::... .||..|..
  Fly   447 ELPDLPRTTLLSTVLKVGNNSLTSLPTVSEHSGYANVSG---LFLSDNNLTSLGSGDQLPDNLTH 508

  Fly   588 LDLRFNNLVTLDDKVLSYLKK--NSIKTKLSGNPWNCDCKSRSVLSILRDHEPLEYDVTLKRCNI 650
            ||:|.|.:.:|.|:.|.:|::  |::...|||||..|.|:|.|:|..:|
  Fly   509 LDVRGNQIQSLSDEFLLFLQEPNNTMTLSLSGNPITCGCESLSLLFFVR---------------- 557

  Fly   651 SPTDCPDVCVCCLDNLTWPSFIVDCRGEGLLQMPSLSSRVTYVDLRNNNLTALSQKNRSSIENRS 715
                                                                             
  Fly   558 ----------------------------------------------------------------- 557

  Fly   716 LKLHLLDNPWSCSCNDIEKINFMKSVSSSIVDFTEIKCSNGEK-LVSINQHIVCPSDLFYYLALA 779
                  .||                  ..:.|..:|.|:..:| ...:....:|||.:.....:.
  Fly   558 ------TNP------------------QRVRDIADIVCTKQKKSFQQMEAFELCPSYVLLISCVV 598

  Fly   780 ISLVATIIALN-FLIWFRQPVLVWFYEHGVCLSLSAKRELDKDKRFDAFLAFTHKDEALLEEFVD 843
            ..||..|..|. |.:.|:|.:.:|.|.:.:||...::.||||||.:|||::::||||.|:.:.:.
  Fly   599 GGLVIVICLLTVFYLMFQQELKIWLYNNNLCLWWVSEEELDKDKTYDAFISYSHKDEELISKLLP 663

  Fly   844 RLERGRPRFQLCFYLRDWLAGESIPDCIGQSIKDSRRIIVLMTENFMNSTWGRLEFRLALHATSR 908
            :||.|...|:||.:.||||.|:.||:.|.:::.||:|:|::::::|::|.|.|:|||:|..||.:
  Fly   664 KLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQ 728

  Fly   909 DRCKRLIVVLYPNVKNFDSLDSELRTYMAFNTYLERSHPNFWNKLIYSMP 958
            |:.||:|::||..:::.:.:|||||.|:..||||:...|.||:||.|:||
  Fly   729 DKRKRIIIILYRELEHMNGIDSELRAYLKLNTYLKWGDPLFWSKLYYAMP 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MstProx	NP_649719.2	leucine-rich repeat	325..345	CDD:275378	4/19 (21%)
		leucine-rich repeat	346..367	CDD:275378	10/20 (50%)
		leucine-rich repeat	563..583	CDD:275378	6/20 (30%)
		leucine-rich repeat	585..610	CDD:275378	9/26 (35%)
		leucine-rich repeat	611..622	CDD:275378	5/10 (50%)
		TIR	823..960	CDD:214587	60/136 (44%)
Tehao	NP_001285901.1	leucine-rich repeat	185..207	CDD:275380	1/21 (5%)
		leucine-rich repeat	209..232	CDD:275380	9/38 (24%)
		leucine-rich repeat	233..261	CDD:275380	7/27 (26%)
		LRR_RI	<261..370	CDD:238064	39/196 (20%)
		leucine-rich repeat	262..284	CDD:275380	4/31 (13%)
		leucine-rich repeat	285..309	CDD:275380	7/27 (26%)
		LRR_8	309..368	CDD:290566	25/132 (19%)
		leucine-rich repeat	310..333	CDD:275380	6/37 (16%)
		leucine-rich repeat	334..357	CDD:275380	14/66 (21%)
		leucine-rich repeat	358..381	CDD:275380	9/37 (24%)
		leucine-rich repeat	445..482	CDD:275380	6/36 (17%)
		LRR_8	459..516	CDD:290566	18/59 (31%)
		leucine-rich repeat	483..505	CDD:275380	8/24 (33%)
		LRR_4	486..521	CDD:289563	13/34 (38%)
		TIR	643..779	CDD:214587	60/136 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I4673
eggNOG	1	0.900	-	-		E2759_KOG4641
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D147327at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24365
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920