Protein Alignment MstProx and Tlr10

DIOPT Version :10

• Sequence 1: NP_649719.2
• Gene: MstProx / 40890
• FlyBaseID: FBgn0015770
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: NP_001139507.2
• Gene: Tlr10 / 305355
• RGDID: 1311569
• Length: 811
• Species: Rattus norvegicus
• Alignment Length: 820
• Identity: 163/820 - (19%)
• Similarity: 310/820 - (37%)
• Gaps: 236/820 - (28%)

  Fly   296 DDLELNIDCSNLGLLQIPPLPIP-------SYGGV------------KLNF---SNNSLSQLPTM 338
            |:.||..:.||:.|.::||...|       ||..:            ||.|   .:||:.||.|.
  Rat    26 DERELISNYSNMALRKVPPDVTPATTILDLSYNLLYQFQSSDCHSFSKLRFLILCHNSIQQLDTK 90

  Fly   339 TLPGYKLVKRLDVSRNRLTNLSINHLPAKLDYLDVSFNEIINMGNDVIKYLRTVPIFKQTGNQWT 403
            .....|.:..||:|.|||.:::.:.| ..|.:||:|||:           ..|:|..::.||
  Rat    91 IFDLNKELSYLDLSYNRLQSITWSSL-VDLRHLDLSFND-----------FDTLPACEEIGN--- 140

  Fly   404 IHCDDKPLLNFFRHLKL------------IIRMKSAEMKPMF--LHSLTELPKGFLKFLGK---H 451
                       .|||:.            :.::.:.:...:|  |::|:...:|.|..|..   |
  Rat   141 -----------MRHLETLGLSGAKIQRSDLQKIANLQFSTVFIGLNTLSHYEEGSLPVLNTTVLH 194

  Fly   452 FI-------WL----GVR------------KQEYYLINEEQLLQSMHRKLNNLNTIMSIYKYMEW 493
            .:       |:    |::            |.::......:.|...:.|.:.|     |:..::.
  Rat   195 IVLPMAANFWVLLCDGMKTSKVVEMSNIGGKSQFVSYETPRTLSVENTKASTL-----IFHKVDL 254

  Fly   494 LHRKLIFVNREYDLFYIRQMAAPCPHKCECCYSRDSLILKIDCRNKFVYNFPDIVARNSRLMG-- 556
            |...|:.|.:    |..|.       ..||...:|.....:..|:...:::.:.|.:...|..
  Rat   255 LWDDLLHVFQ----FVWRT-------SVECFQIQDLTFGGMASRDHSSFDYSNTVMKAVILESIH 308

  Fly   557 ------KQNMSSPMELHLSKNNISNITI--AMLPKEL------RFLDLRFNNLVTLDDKVLSYLK 607
                  .||   .:.|..::.::.|:||  |.:|..|      .|..|.|.|.:..||...:.::
  Rat   309 FRIFFIPQN---KIYLFFTQMDLENLTISDAQMPHLLFPSHPQSFQHLNFANNILTDDLFKNPIQ 370

  Fly   608 KNSIKT-KLSGNPWNCDCKSRSVLSILRDHEPLEYDVTLKRCNISPTDCPDVCVCCLDNLTWPSF 671
            ...:|| .|.||    ..::.|::|:..:|..|.: :.|.: |:......:.|:       ||..
  Rat   371 MPYLKTLVLRGN----QLETLSLVSLFANHTSLLH-LDLSQ-NLLQHGNGEKCM-------WPDT 422

  Fly   672 IVDCRGEGLLQMPS----------LSSRVTYVDLRNNNLTALSQ--------------------- 705
            ::      ||.:.|          |...:..:||.||.:.|:.:
  Rat   423 LI------LLNLSSNKFDGSVFRCLPKSIQTLDLNNNKIRAVPKEIIYLKSLRELSIAFNFLTDL 481

  Fly   706 ------KNRSSIENRSLKLHLLDNP---WSCSCNDIEKINFMKSVSSSIVDFTEI----KCSNG- 756
                  |..||:   :::::|:.:|   :..||.:::.:|..::....|.:|.:.    |.|.|
  Rat   482 PGCDHFKQLSSL---NIEMNLILSPSLDFFQSCQEVKTLNAGRNPFRCICEFRDFIWLEKHSKGL 543

  Fly   757 ----------EKLVSIN---------QHIVCPSDLFYYLALAISLVATIIALNFLIWF--RQPVL 800
                      |..:|:.         ..:.|.:.|     |.:::|..|:.|..::.|  .:..:
  Rat   544 MSGWPDSYACEYPLSLKGTPLKDVYLPELACNTTL-----LIVTIVLVILVLGLVVAFCILKFDM 603

  Fly   801 VWFY---------EHGVCLSLSAKRELDKDKRFDAFLAFTHKDEALLE-EFVDRLERGRPRFQLC 855
            :|:.         :|.:  ..:.:.|..:..:|.||:::...|...:: |.:..||.......||
  Rat   604 LWYLRVLAQCIRTQHRI--RKTVREERKRSIQFHAFISYAAHDSVWVKNELIPNLETEDGSVLLC 666

  Fly   856 FYLRDWLAGESIPDCIGQSIKDSRRIIVLMTENFMNSTWGRLEFRLALHATSRDRCKRLIVVLYP 920
            ...|::....||.:.|....:.|.:.|.:::.||:.:.|...|..||.|...||....:|.:|..
  Rat   667 LPERNFDPDRSIAENIISCTEKSYKSIFVLSPNFVQNGWCHNELYLAHHNPFRDNYDYIIPILLE 731

  Fly   921 NVKNF--DSLDSELRTYMAFNTYLE-----RSHPNFWNKL 953
            .:.::  .:...:|:..:....|||     |.|..||..|
  Rat   732 PIPSYCVPTKFPKLKALLEKKVYLEWPKDRRKHGLFWANL 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MstProx	NP_649719.2	PRK15370	<315..>398	CDD:185268	27/104 (26%)
		leucine-rich repeat	325..345	CDD:275378	7/22 (32%)
		leucine-rich repeat	346..367	CDD:275378	7/20 (35%)
		TIR	823..960	CDD:214587	35/139 (25%)
Tlr10	NP_001139507.2	None