Protein Alignment MstProx and LOC100498493

DIOPT Version :9

• Sequence 1: NP_649719.2
• Gene: MstProx / 40890
• FlyBaseID: FBgn0015770
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: XP_002941870.2
• Gene: LOC100498493 / 100498493
• XenbaseID: XB-GENE-5824069
• Length: 936
• Species: Xenopus tropicalis
• Alignment Length: 916
• Identity: 197/916 - (21%)
• Similarity: 342/916 - (37%)
• Gaps: 230/916 - (25%)

  Fly   158 NAYKTVEN-QQIAL--------DNL-----IFNGKSHLRSLTFIGFQI--ENLSTKPFAQFINLK 206
            ||:|.:|: :.:|:        :||     .|:...:||.|:..||::  ..|...||:  .:|.
 Frog   121 NAFKGLESLESLAISFLGHSKCNNLSIPTDAFSNLYYLRDLSIEGFKLVKSMLIHLPFS--TSLY 183

  Fly   207 RMVL-TNCTV---------RNLTFLRTLQKSLEHLELDIDNEVDLKYFTNFSSLKFMKVRNYIPN 261
            .:.| |||..         :||.|:..|......:|     .|.|::..|.|   ...:...:..
 Frog   184 SLSLPTNCITDLFHVFHIFQNLIFIHNLDVGSNKIE-----RVSLQHDLNIS---LPNITELVLE 240

  Fly   262 KNFTALICTHKNCNFIRGINGLECPKLCQCLYIIDDLELNI-DCSNLGLLQIPPLPIPSYGGVKL 325
            ||  .||...:|.....||:          |..:...:||: |..|.|:..:..|.:.|.....:
 Frog   241 KN--PLILIQQNALARFGIH----------LLNLGFTKLNLEDILNAGVENLKSLSLTSACRRAI 293

  Fly   326 NFSNNSLSQLPTMTLPGYKLVKRLDVSRNRLTNLSINHLPAKLDYLDVSFNEIINMGNDVI---- 386
            |.::...|......|      |.|....||.:.:...      |:|..|..|.:|:.::.|
 Frog   294 NKTHTLCSIAQRFQL------KSLSAPVNRFSGIYTK------DFLGCSSLEFLNLNHNHIHIVD 346

  Fly   387 -KYLRTVPIFKQTGNQWT-IHCDDKPLL---NFFRHLKLII----RMKSAEMKPMF-LHSLTE-- 439
             ..|.|:|..|:....:: :|.:..||.   ||...::.:.    |:...:.|..| :..||:
 Frog   347 PDLLYTLPKLKELHLSYSLLHMNLCPLSYQDNFTSSVEALYFIGNRITVLKNKQFFCMTKLTDLL 411

  Fly   440 LPKGFLKFLGKHFIWLGVRKQEYYLINEEQLLQSMHRKLNNLNTIMSIY---KYMEWLHR----- 496
            |.:..::.:.:...| |:.......:...:|.......|:.|:.:|.:|   ..||.:.|
 Frog   412 LARNGIEHIEESAFW-GLNDLRVLDLRNNRLTSLQISSLSGLSNLMELYLQNNVMESMQRYSLKW 475

  Fly   497 --KL---------------IFVNRE---------YDLFYIRQMAAPCPHKCECCYSRDSLI---- 531
              ||               :|.|.|         |...::.:.||.         |..||.
 Frog   476 QTKLRLVKIGFVSVSVSFELFPNTETLDIQTTGKYITVFMNETAAS---------SLKSLSVNGS 531

  Fly   532 ---LKIDCRNKFVYNFPDI-VARNSRLMGKQNMSSPMELHLSKNNISNITI----AMLPKELRFL 588
               |.|.|.::|.....:: |..|:.|:...:....:| |.  .|:.||..    |.|.:
 Frog   532 HVELDIKCGHQFFSTLRELKVINNNGLISCSHYGYQLE-HF--ENLENIQYHFSGAPLTR----- 588

  Fly   589 DLRFNNLVTLDDKVLSYLKKNSIKTKLSGN-PWNCDCKSRSVLSILRDHEPLEYDVTLKRCNISP 652
            ::.|:|:..|..     |:..::.|.|..| |.|         .:......||   .||..|
 Frog   589 NVNFSNIANLRS-----LEVENLATALDPNVPPN---------DLFHKLHKLE---VLKLFN--- 633

  Fly   653 TDCPDVCVCCLDNLTWPSFIVDCRGEGLLQMPSLSSRVTYVDLRNNNLTALS---QKNRSSIENR 714
                    |....:| .:.:.|.|...:|.|            :|..:.|:.   |...|.:|
 Frog   634 --------CGFKYMT-TALLKDMRSLRVLVM------------KNQMILAVDPGLQNTLSPLE-- 675

  Fly   715 SLKLHLLDNPWSCSCNDI--------EKINFMKSVSS----------SIVDFTEIKCSNGEKLVS 761
              .::.:|..:.|.|::.        :|..|:..:.|          ::|:|:|..|
 Frog   676 --FIYFIDVTFQCDCDNSWFVTWALEDKHTFVSGICSLFCLQLNKKFNLVNFSESSC-------- 730

  Fly   762 INQHIVCPSDLFYYLALAISLVATIIALNFLIWFRQPVLVWFYEHGVCL-SLSAKRELDKDKRFD 825
             .|.|    |...::....||:..|:.......|...::..||...:.| .|..|........:|
 Frog   731 -RQEI----DFMLFVITFTSLLLFIVLTMLCNIFNSDIIQLFYVFQIWLKKLRGKTNNPIAYEYD 790

  Fly   826 AFLAFTHKDEA-LLEEFVDRL-ERGRPRFQLCFYLRDWLAGESIPDCIGQSIKDSRRIIVLMTEN 888
            ||:::..:|:. ::...|..| |:||...:||.:.||:|.|:.|.|.|..||..||:.|.|::.|
 Frog   791 AFVSYCSRDQGWVVNYLVPNLEEKGRNTIKLCLHNRDFLVGKDIVDNIMDSIYKSRKTICLISYN 855

  Fly   889 FMNSTWGRLEFRLALHATSRDRCKRLIVVLYPNVKNFD-SLDSELRTYMAFNTYL-----ERSHP 947
            ::.|.|..||.|:|.:....::...||:|...::..:. |....|...:...||:     |....
 Frog   856 YLQSDWCSLEMRMATYKLLAEKNDDLILVFLESISGYHLSAYHRLARIVRKKTYIDWPQEENEQA 920

  Fly   948 NFWNKL 953
            .||.:|
 Frog   921 EFWERL 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MstProx	NP_649719.2	leucine-rich repeat	325..345	CDD:275378	3/19 (16%)
		leucine-rich repeat	346..367	CDD:275378	4/20 (20%)
		leucine-rich repeat	563..583	CDD:275378	7/23 (30%)
		leucine-rich repeat	585..610	CDD:275378	4/24 (17%)
		leucine-rich repeat	611..622	CDD:275378	4/11 (36%)
		TIR	823..960	CDD:214587	42/139 (30%)
LOC100498493	XP_002941870.2	leucine-rich repeat	60..82	CDD:275380
		leucine-rich repeat	83..105	CDD:275380
		leucine-rich repeat	106..128	CDD:275380	3/6 (50%)
		internalin_A	143..>394	CDD:380193	63/284 (22%)
		leucine-rich repeat	182..207	CDD:275380	7/24 (29%)
		leucine-rich repeat	208..233	CDD:275380	6/32 (19%)
		leucine-rich repeat	234..279	CDD:275380	13/56 (23%)
		leucine-rich repeat	308..331	CDD:275380	7/34 (21%)
		leucine-rich repeat	332..355	CDD:275380	5/22 (23%)
		leucine-rich repeat	356..382	CDD:275380	6/25 (24%)
		leucine-rich repeat	383..406	CDD:275380	3/22 (14%)
		LRR_8	405..463	CDD:404697	10/58 (17%)
		leucine-rich repeat	407..430	CDD:275380	5/23 (22%)
		leucine-rich repeat	431..454	CDD:275380	3/22 (14%)
		leucine-rich repeat	455..478	CDD:275380	5/22 (23%)
		TIR	788..930	CDD:214587	42/139 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D147327at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010