DRSC/TRiP Functional Genomics Resources

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Protein Alignment MstProx and cd180

DIOPT Version :9

Sequence 1:NP_649719.2 Gene:MstProx / 40890 FlyBaseID:FBgn0015770 Length:965 Species:Drosophila melanogaster
Sequence 2:XP_031762487.1 Gene:cd180 / 100489673 XenbaseID:XB-GENE-489949 Length:571 Species:Xenopus tropicalis


Alignment Length:621 Identity:124/621 - (19%)
Similarity:202/621 - (32%) Gaps:200/621 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 DPNIFIISPI-SKENRLKLNELIVSDTSYPI-------------RAVDYLR----QLGVETVT-- 103
            |....:::|: |....|.:.|:|....|:..             ||:...|    .|.:|.:.  
 Frog    24 DEECKVVTPVQSTTPGLVITEVIYGTISFEFCFSRTFSRNSHFQRAISAARLFPGPLALELINVK 88

  Fly   104 --------RFENQINSFKVIERDVHYINGPKSLKIIIQSNLYLNEIIEYINKTTDNVNEIIINAY 160
                    |....:....|..|....:....||..:..:.....:.|..::.|..|:|.:    |
 Frog    89 VDWAHVQFRSMKHLRPLPVSHRQYCLVKEINSLFALYHTTFMRLKCISPLDLTRCNINLL----Y 149

  Fly   161 KTVENQQIALDNLIFNGKSHLRSLTFIGFQIENLSTKPFAQFINLKRMVLTNCTVRNLTFLRTLQ 225
            :.|           |....||.:|..||..|..::...|...:.||.:.|....:.|:||:..  
 Frog   150 EDV-----------FQNNIHLNTLVLIGNPILYIAASAFNGPLALKHLFLQQIPLTNVTFIPL-- 201

  Fly   226 KSLEHLELDIDNEVDLKYFTNFSSLKFMKVRNYIPNKNFTALICTHKNCNFIRGINGLECPKLCQ 290
            :.|:|||       .|.:..||  :..:::.:..|.||...| ....|| .|             
 Frog   202 EHLQHLE-------TLSFGNNF--ISSLQLPHNFPIKNLRVL-DFQSNCXKI------------- 243

  Fly   291 CLYIIDDLELNIDCSNLGLL-------QIPPLPIPSYGGVKLNFSNN--SLSQLPTMT-LPGYKL 345
               :..|:|:....:||.|:       .|.|....|.....|:...|  .|:.|.:.| ......
 Frog   244 ---LAADVEILKQSNNLSLILKGNDIEYIEPNSFDSVNLYSLDLKGNRGDLANLLSSTAFSCLTT 305

  Fly   346 VKRLDVSRNRLTNLSINHLPAKLDYLDVSFNEIINMGNDVIKYLRTVPIFKQTGNQWTIHCDDKP 410
            ::|||     ||...:..||. |.||::|...|.....:::|.|                 :.:.
 Frog   306 IQRLD-----LTGTHVESLPL-LKYLNLSRMNINASNENLLKGL-----------------ESQT 347

  Fly   411 LLNFFRHLKLIIRMKSAEMKPMFLHSLTELPKGFLKFLGKHFIWLGVRKQEYYLINEEQLLQSMH 475
            .||.             |..|    |:.||...||:.|  |.        |..::....|....|
 Frog   348 FLNM-------------ERPP----SIWELYNIFLQAL--HL--------EVLILLSCNLTAIEH 385

  Fly   476 RKLNNLNTIMSIYKYMEWLHRKL-IFVNREY-DLFYIRQMAAPCPHKCECCYSRDSLILKIDCRN 538
            |..:.|..:    :|.:..|.|: ||.:..: ||.:|.                           
 Frog   386 RAFHKLAKL----QYEDLRHNKITIFSSNAFRDLSHIH--------------------------- 419

  Fly   539 KFVYNFPDIVARNSRLMGKQNMSSPMELHLSKN-------NISNITIAMLPKELRFLDLRFNNLV 596
               .||            ..||.|.:..||..|       |:|:..|..|....:||     |..
 Frog   420 ---LNF------------ASNMISDIASHLLHNISGTSAINLSHNPIDCLCFNFQFL----XNEK 465

  Fly   597 TLDDKVLSYLKKNSIKTKLSGNPWNCDCKSRSVLSI 632
            ..:||.::          |.|:|.:.:..:.|.|.:
 Frog   466 IFEDKSIT----------LCGSPKSIEGTTLSALQL 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MstProxNP_649719.2 leucine-rich repeat 325..345 CDD:275378 5/22 (23%)
leucine-rich repeat 346..367 CDD:275378 7/20 (35%)
leucine-rich repeat 563..583 CDD:275378 7/26 (27%)
leucine-rich repeat 585..610 CDD:275378 5/24 (21%)
leucine-rich repeat 611..622 CDD:275378 3/10 (30%)
TIR 823..960 CDD:214587
cd180XP_031762487.1 inl_like_NEAT_1 <71..>326 CDD:411101 64/303 (21%)
leucine-rich repeat 138..158 CDD:275380 6/34 (18%)
leucine-rich repeat 159..182 CDD:275380 6/22 (27%)
leucine-rich repeat 183..206 CDD:275380 7/24 (29%)
leucine-rich repeat 207..230 CDD:275380 6/31 (19%)
leucine-rich repeat 231..256 CDD:275380 6/41 (15%)
leucine-rich repeat 257..278 CDD:275380 5/20 (25%)
leucine-rich repeat 279..305 CDD:275380 5/25 (20%)
leucine-rich repeat 322..345 CDD:275380 7/39 (18%)
LRR_8 369..427 CDD:404697 17/111 (15%)
leucine-rich repeat 370..393 CDD:275380 5/30 (17%)
leucine-rich repeat 394..417 CDD:275380 7/26 (27%)
leucine-rich repeat 418..440 CDD:275380 9/63 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D147327at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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