Protein Alignment MstProx and tlr2

DIOPT Version :9

• Sequence 1: NP_649719.2
• Gene: MstProx / 40890
• FlyBaseID: FBgn0015770
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: XP_002933537.2
• Gene: tlr2 / 100485771
• XenbaseID: XB-GENE-481145
• Length: 780
• Species: Xenopus tropicalis
• Alignment Length: 829
• Identity: 178/829 - (21%)
• Similarity: 319/829 - (38%)
• Gaps: 246/829 - (29%)

  Fly   289 CQCLYIIDDLELNIDCSNLGLLQIPP-LPIPSYGGVKLNFSNNSL-----------SQLPTMTLP 341
            |.|     |......||::....||. ||....|   ||.|:|::           .||.|:.|.
 Frog    26 CPC-----DAANFCHCSSMHWEAIPSGLPRDVRG---LNLSSNAIQIVTETDLQPYDQLQTLLLQ 82

  Fly   342 GYKLV--------------KRLDVSRNRLTNLS---INHLPAKLDYLDVSFNEIINMGND----V 385
             |..:              :.||:|.|.|::||   ..:| ..|.:|::..|:.:.:||:    .
 Frog    83 -YNAIHTINDGSFQPLGNLEELDLSYNNLSHLSSAWFRNL-YNLKHLNLLGNQYLTLGNNSLFAS 145

  Fly   386 IKYLRTVPIFKQTGNQWTIHCDDKPLLNFFRHLKLIIRMKSAEMKPMFLHSLTELPKGFLKFLGK 450
            :..||::    |.|||     |...:...  |.:.:.|:...|:|...|....|.....:|.:..
 Frog   146 LSSLRSL----QFGNQ-----DFSAIQKL--HFESLERLNILEIKAAQLGLYEEGSLAAIKQINH 199

  Fly   451 HFIWLGVRKQEYYL---INEEQLLQSMHRKLNNLNTIMSIYKYMEWLHRKLIFVNREYDLFYIRQ 512
            ..:.:.::.....|   |:...||:....:..:...:.::....:...:.|:|.|
 Frog   200 AVLTVNIQNLRALLNDFIHSVTLLEMKDMQFGDAADVKAMVILNDTSIKYLVFRN---------- 254

  Fly   513 MAAPCPHKCECCYSRD---SLILKIDCRNKFVYNFPDIVARNSRLMGKQNMSSPMELHLSKNNIS 574
                       |...|   |.:|:|   .:...|..|.:..:|.|.| ...:||:   :..:..|
 Frog   255 -----------CIITDQSASRLLEI---FQTYRNITDFILDDSTLYG-TGTASPV---IGDDPFS 301

  Fly   575 NITIAM-----LPKELRFLDLR--------FNNLVTLDDKV-------------LSY--LKKNSI 611
             :|.|:     :||...|.||:        |.|:..:|.||             |.|  |..|.:
 Frog   302 -VTTAIINKLHIPKFFLFSDLQGIYKLASNFKNIACIDSKVFLMPCAFSRSFSSLQYLDLSGNLL 365

  Fly   612 KTKL---------SGNPW------NCDCKSRSVLSILR-------------------------DH 636
            ...|         .|..|      |.   ||::|:.||                         ..
 Frog   366 SDNLLASSACAFEGGGAWPILQTLNV---SRNLLTSLRRLAQITSGLKYLTNLDVSQNNFGELST 427

  Fly   637 EPLEYDVTLKRCNISPTDCPDVCVCCLDNLTWPSFIVDCRGEGL----LQMPSLSSRVTYVDLRN 697
            ...::..:||..|||.:...:: .|....|.    |:|.....|    ::||:|    |.:.:.|
 Frog   428 STCQWPKSLKYLNISSSQMSNI-TCIPPTLQ----ILDVSSNYLTVFTIKMPNL----TELYISN 483

  Fly   698 NNLTALSQ-------------KNR---------------SSIENRSLKLHLLDNPWSCSCNDIEK 734
            |.|:.|.:             :|:               ::::.|       ||.:.|||   :.
 Frog   484 NRLSKLPEGMYFPRLFMLSIDRNKLNDFYQSDLDLFPQLTTLDGR-------DNNYLCSC---QF 538

  Fly   735 INFMKSVSSSIVDF-TEIKCSN-----GEKLVSIN-QHIVCPSDLFYYLA--LAISLVATIIAL- 789
            ::||.|.:.::|.: .:..|.:     |:::...| ..:||...|...|:  |.|:|||.|.||
 Frog   539 LSFMHSHTIALVGWPDDYICDSPSSVRGKRIQDANLPPLVCHKTLIVTLSCILLIALVAAIAALC 603

  Fly   790 NFL--IWFRQPVLVWFYEHGVCLSLSAKRE----LDKDKRFDAFLAFTHKDEALLEE-FVDRLER 847
            :||  :|:.:....|         |.|||:    .|::..::.|::::.:|...:|. .|.:||.
 Frog   604 HFLHVVWYAKMTWAW---------LKAKRKPLKNCDREICYNGFVSYSERDSEWVENMMVPKLEN 659

  Fly   848 GRPRFQLCFYLRDWLAGESIPDCIGQSIKDSRRIIVLMTENFMNSTWGRLEFRLALHATSRDRCK 912
            ..|..:||.:.||::.|:.|.|.|..:::.|.:.:.:::|:|:.|.|.:.|...:......:...
 Frog   660 AVPPMKLCLHKRDFVPGKWIIDNIIDAMEKSYKTVFVLSEHFVRSEWCKYELEFSHFRLFDENND 724

  Fly   913 RLIVVLYPNVKNFDSLDS---ELRTYMAFNTYL-----ERSHPNFWNKL 953
            ..|::|...::| :::..   :||..|...|||     |.....||:.|
 Frog   725 TAILILLEPIEN-ETVPKRFCKLRKLMNTKTYLEWPTDEEQQEVFWDNL 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MstProx	NP_649719.2	leucine-rich repeat	325..345	CDD:275378	9/30 (30%)
		leucine-rich repeat	346..367	CDD:275378	8/37 (22%)
		leucine-rich repeat	563..583	CDD:275378	4/24 (17%)
		leucine-rich repeat	585..610	CDD:275378	11/47 (23%)
		leucine-rich repeat	611..622	CDD:275378	3/25 (12%)
		TIR	823..960	CDD:214587	34/140 (24%)
tlr2	XP_002933537.2	internalin_A	55..>247	CDD:380193	40/204 (20%)
		leucine-rich repeat	55..75	CDD:275378	4/19 (21%)
		LRR_8	75..133	CDD:404697	15/59 (25%)
		leucine-rich repeat	76..99	CDD:275378	4/23 (17%)
		leucine-rich repeat	100..123	CDD:275378	8/23 (35%)
		leucine-rich repeat	124..148	CDD:275378	5/23 (22%)
		leucine-rich repeat	149..162	CDD:275378	7/21 (33%)
		leucine-rich repeat	322..352	CDD:275378	5/29 (17%)
		PRK15370	<353..>508	CDD:185268	32/166 (19%)
		leucine-rich repeat	355..382	CDD:275380	6/26 (23%)
		leucine-rich repeat	386..411	CDD:275380	6/27 (22%)
		leucine-rich repeat	412..435	CDD:275380	0/22 (0%)
		leucine-rich repeat	436..455	CDD:275380	6/19 (32%)
		leucine-rich repeat	456..475	CDD:275380	5/22 (23%)
		leucine-rich repeat	476..497	CDD:275380	6/24 (25%)
		leucine-rich repeat	498..521	CDD:275380	1/22 (5%)
		TIR	634..779	CDD:214587	34/140 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D147327at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24365
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020