DRSC/TRiP Functional Genomics Resources

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Protein Alignment nxf4 and NXF2B

DIOPT Version :9

Sequence 1:NP_731156.1 Gene:nxf4 / 40884 FlyBaseID:FBgn0051501 Length:301 Species:Drosophila melanogaster
Sequence 2:NP_001093156.1 Gene:NXF2B / 728343 HGNCID:23984 Length:626 Species:Homo sapiens


Alignment Length:197 Identity:56/197 - (28%)
Similarity:81/197 - (41%) Gaps:35/197 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    96 FFVDSYDVASALFRRGWVDNQIWLKV-SDRMPKIWI-----------------NSILRLHLTMVL 142
            |||.....||||       ..:..|: .|...||.|                 ..:..|.|||  
Human   166 FFVQDASAASAL-------KDVSYKIYDDENQKICIFVNHSTAPYSVKNKLKPGQMEMLKLTM-- 221

  Fly   143 LDRYDPVERSLDLTLFYKDKALCGE--FFALAESNCMSTVLGIVDREMPELERLILDGNHLTNLW 205
            ..||:..:::|||.....|..|.|.  ...|...|||:..|.|::|..|||..|.|..|.|..|.
Human   222 NKRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAATLKIIERNFPELLSLNLCNNKLYQLD 286

  Fly   206 VFRKVERRFPRLHSISLKHNDIENIYSLRNLQFLPLAELNLLDNPL------PAGYEKEVLDIWP 264
            ....:..:.|::.:::|..|.:|:.:.|..::.|.|.||.|..|||      .:.|...:.|.:|
Human   287 GLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLKLEELWLEGNPLCSTFSDQSAYVSAIRDCFP 351

  Fly   265 SL 266
            .|
Human   352 KL 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nxf4NP_731156.1 leucine-rich repeat 150..190 CDD:275382 13/41 (32%)
LRR_4 189..235 CDD:289563 13/45 (29%)
leucine-rich repeat 191..216 CDD:275382 6/24 (25%)
leucine-rich repeat 217..240 CDD:275382 4/22 (18%)
NXF2BNP_001093156.1 Tap-RNA_bind 121..203 CDD:312616 12/43 (28%)
leucine-rich repeat 229..271 CDD:275382 13/41 (32%)
LRR_8 270..332 CDD:316378 19/61 (31%)
LRR 1 271..296 7/24 (29%)
leucine-rich repeat 272..297 CDD:275382 6/24 (25%)
LRR 2 297..320 4/22 (18%)
leucine-rich repeat 298..321 CDD:275382 4/22 (18%)
LRR 3 321..348 8/26 (31%)
leucine-rich repeat 322..352 CDD:275382 9/29 (31%)
LRR 4 349..376 2/5 (40%)
NTF2_like 391..543 CDD:324324
TAP_C 570..623 CDD:197882
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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