DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nxf4 and Nxf2

DIOPT Version :9

Sequence 1:	NP_731156.1	Gene:	nxf4 / 40884	FlyBaseID:	FBgn0051501	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	XP_002730329.2	Gene:	Nxf2 / 308653	RGDID:	1559530	Length:	619	Species:	Rattus norvegicus

Alignment Length:	356	Identity:	83/356 - (23%)
Similarity:	143/356 - (40%)	Gaps:	85/356 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RNNSSEGPLCHSTPRSV-----KGDFKFESK------NGARLP---------RSIYGWYRVLIYS 50
            |||....|   .||.:|     |..:.:|.:      |..:..         |:...||:|.|.|
  Rat    70 RNNHFNYP---GTPYAVGLKRRKERYSYEDRYFLTVWNDRKTEECEDLYAERRATERWYKVTIPS 131

  Fly    51 TDRRLTFNRVLRRIR--CILTPLKINPRYKHTGGEQDTAEDSWALFTFFVDSYDVASALFRRGWV 113
             .|:.....::..|:  |.:..:.::..|     :::.|.       |||....:||||
  Rat   132 -GRKYEKTWLINSIQKLCTVPFVPVDFHY-----DKNRAR-------FFVQDAKIASAL------ 177

  Fly   114 DNQIWLKVSDR---------MPKIWINSILRL-------HLTMVLLDRYDPVERSLDLTLFYKDK 162
             ..:.||:.|.         .|.:...|:...       ||.:.::.|||..:::|||..|..|:
  Rat   178 -KDVNLKICDETSRKISLFVSPSVVPYSVQNKFSSEQMEHLKISIMKRYDASQKALDLEKFRFDQ 241

  Fly   163 ALCGE--FFALAESNCMSTVLGIVDREMPELERLILDGNHLTNLWVFRKVERRFPRLHSISLKHN 225
            .|..:  ...|...:||...|.|::..:|||..|.|..|.|..|.....:..:.|::..::|..|
  Rat   242 DLMDKDIDMMLNRRSCMVATLQIIESNIPELLSLNLKNNKLYQLDGLSDMTEKAPQVKILNLSRN 306

  Fly   226 DIENIYSLRNLQFLPLAELNLLDNPL------PAGYEKEVLDIWPSLQVLN-KIQVTP---DPAM 280
            .:::|:.|..::.|.|.||.|..||.      .:.|...|.|::|.|..|: :..:.|   |...
  Rat   307 KLKSIFELEKVKELKLEELWLEGNPFCNCYLDDSEYISAVRDLFPKLLRLDGRELIVPTGMDIEA 371

  Fly   281 MQLVERVLQHTGTK----------REFFRFF 301
            .||.::.  |..|:          :|::.|:
  Rat   372 PQLCKKT--HNETELIKNLVLRFLKEYYLFY 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nxf4	NP_731156.1	leucine-rich repeat	150..190	CDD:275382	11/41 (27%)
		LRR_4	189..235	CDD:289563	13/45 (29%)
		leucine-rich repeat	191..216	CDD:275382	6/24 (25%)
		leucine-rich repeat	217..240	CDD:275382	4/22 (18%)
Nxf2	XP_002730329.2	Tap-RNA_bind	121..203	CDD:286271	21/101 (21%)
		leucine-rich repeat	229..271	CDD:275382	11/41 (27%)
		LRR_4	270..316	CDD:289563	13/45 (29%)
		leucine-rich repeat	272..297	CDD:275382	6/24 (25%)
		leucine-rich repeat	298..321	CDD:275382	4/22 (18%)
		leucine-rich repeat	322..352	CDD:275382	9/29 (31%)
		NTF2_like	385..534	CDD:298832	2/16 (13%)
		TAP_C	558..619	CDD:197882
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3763
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810