DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10029 and EPS1

DIOPT Version :10

Sequence 1:NP_649716.1 Gene:CG10029 / 40883 FlyBaseID:FBgn0037498 Length:410 Species:Drosophila melanogaster
Sequence 2:NP_012261.1 Gene:EPS1 / 854812 SGDID:S000001267 Length:701 Species:Saccharomyces cerevisiae


Alignment Length:428 Identity:79/428 - (18%)
Similarity:129/428 - (30%) Gaps:198/428 - (46%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 SNELVLLSFYTDWCRFSQILQPIFEEAAAKVIQKFPENGR---VILGKVNC-DTEDILADQFDIL 103
            |..|.::.||:.:|...:.|.|::.|    ..::|.|..:   :...:||| ::.|:..|: :|.
Yeast    47 SKGLHIIDFYSPYCPHCKHLAPVWME----TWEEFKEESKTLNITFSQVNCIESADLCGDE-NIE 106

  Fly   104 KYPTIKIVR-NGLIGNQEYRGQRSVEALFQFVEKELSDPIKEFHNID------------------ 149
            .:|.|::.. :|.| .......|:.|:|..|..:|..||    :|:|                  
Yeast   107 YFPEIRLYNPSGYI-KSFTETPRTKESLIAFARRESMDP----NNLDTDLDSAKSESQYLEGFDF 166

  Fly   150 --------------------DLKNVDVGYGIVIGYFISKDHAEYDN------YRRVASLLRND-- 186
                                |:||.|             |..|:.|      ::|...::...  
Yeast   167 LELIAGKATRPHLVSFWPTKDMKNSD-------------DSLEFKNCDKCHEFQRTWKIISRQLA 218

  Fly   187 -----------------CRFLVGFGDLTK------DLRPPGKNALIFRGDPSIPN--------HK 220
                             |..| |||||.|      |..|  |.||:      :||        :.
Yeast   219 VDDINTGHVNCESNPTICEEL-GFGDLVKITNHRADREP--KVALV------LPNKTSNNLFDYP 274

  Fly   221 NQYSEYLGNMTSFKELTFWIDKTCVPLVREVTFDNAEELSEEGLPFVLLFYNKDDLSPIQEFKNA 285
            |.||........|...||...|                                       |.|.
Yeast   275 NGYSAKSDGYVDFARRTFTNSK---------------------------------------FPNI 300

  Fly   286 IQSQMENETR--VIFLTAEGEVFKHPLFHLGKSPSDLPVIAIDSFMHMYLFPRFQDIYDPGALKK 348
            .:.::|.:..  :.||...|.|..:.: ||..|                        |||..:  
Yeast   301 TEGELEKKANRDIDFLQERGRVTNNDI-HLVFS------------------------YDPETV-- 338

  Fly   349 FIDDLFSGALHYNYHVAQQAKEDLESIIDPTEDLPVVH 386
            .|:|.                :.||.:|:|...:|.::
Yeast   339 VIEDF----------------DILEYLIEPLSKIPNIY 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10029NP_649716.1 PDI_a_ERp44 27..134 CDD:239294 23/95 (24%)
PDI_b_ERp44 142..237 CDD:239368 29/171 (17%)
PDI_b'_ERp44 248..357 CDD:239370 15/110 (14%)
EPS1NP_012261.1 Thioredoxin 33..139 CDD:395038 24/97 (25%)
PTZ00102 <404..>472 CDD:240266
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.