Protein Alignment CG10029 and PDI1

DIOPT Version :10

• Sequence 1: NP_649716.1
• Gene: CG10029 / 40883
• FlyBaseID: FBgn0037498
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_009887.1
• Gene: PDI1 / 850314
• SGDID: S000000548
• Length: 522
• Species: Saccharomyces cerevisiae
• Alignment Length: 457
• Identity: 93/457 - (20%)
• Similarity: 187/457 - (40%)
• Gaps: 94/457 - (20%)

  Fly     9 ILYSLAILVSLHSLVAGNSSVVAVTHENLQGIIDSNELVLLSFYTDWCRFSQILQPIFEEAAAKV 73
            :|.:.::.....::...:|:||.:..::....|.|::|||..|:..||...:.:.|.:.:||..:
Yeast    14 LLLASSVFAQQEAVAPEDSAVVKLATDSFNEYIQSHDLVLAEFFAPWCGHCKNMAPEYVKAAETL 78

  Fly    74 IQKFPENGRVILGKVNCDTEDILADQFDILKYPTIKIVRNGLIGNQ-EYRGQRSVEALFQFVEKE 137
            ::|     .:.|.:::|.....|..:.:|..:|::||.:|..:.|. :|.|.|:.||:.||:.|:
Yeast    79 VEK-----NITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQ 138

  Fly   138 LSDPIKEFHNIDDLK-----------------NVDVGYGIVIGYFISKDHAEYDNYRRVASLLRN 185
             |.|....  :.||.                 .:|..:...   |.|..:..:::|..|::...:
Yeast   139 -SQPAVAV--VADLPAYLANETFVTPVIVQSGKIDADFNAT---FYSMANKHFNDYDFVSAENAD 197

  Fly   186 DCRFLVGFGDLTKDLRPPGKNALIFRGDPSIPNHKNQYSEYLGNMTSFKELTFWIDKTCVPLVRE 250
            |        |....:..|..     ..:|.:.|.|   ...:.:...|::   |:....:|...|
Yeast   198 D--------DFKLSIYLPSA-----MDEPVVYNGK---KADIADADVFEK---WLQVEALPYFGE 243

  Fly   251 VTFDNAEELSEEGLPFVLLFYNKDDLSPIQEFKNAIQSQMENETRVI--FLTAEGEVF-KH---- 308
            :......:..|.|||...||||  |...::|:| .:.:::..:.|.:  |::.:...| :|
Yeast   244 IDGSVFAQYVESGLPLGYLFYN--DEEELEEYK-PLFTELAKKNRGLMNFVSIDARKFGRHAGNL 305

  Fly   309 ------PLFHLGKSPSD----LPVIAIDSFMHMYLFPRFQD--IYDPGALKKFIDDLFSGAL--- 358
                  |||.:.....|    ||.::.::      |....|  :.:..|::..:.|...|..
Yeast   306 NMKEQFPLFAIHDMTEDLKYGLPQLSEEA------FDELSDKIVLESKAIESLVKDFLKGDASPI 364

  Fly   359 --------HYNYHVAQQAKEDLESII-DPTEDLPVVHESKF----KDLKPSKHRY--TLVNRTRD 408
                    :.:..|.|...::.:.|: ||.:|:.|::.:.:    |.|.|:....  |..|.|.|
Yeast   365 VKSQEIFENQDSSVFQLVGKNHDEIVNDPKKDVLVLYYAPWCGHCKRLAPTYQELADTYANATSD 429

  Fly   409 EL 410
            .|
Yeast   430 VL 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10029	NP_649716.1	PDI_a_ERp44	27..134	CDD:239294	30/107 (28%)
		PDI_b_ERp44	142..237	CDD:239368	14/111 (13%)
		PDI_b'_ERp44	248..357	CDD:239370	26/127 (20%)
PDI1	NP_009887.1	ER_PDI_fam	32..492	CDD:273457	92/439 (21%)